Healthtech Startups

Sangamo Therapeutics develops gene-editing therapeutics using zinc finger and modular integrase platforms to treat genetic diseases including hemophilia, Fabry disease, and neuropathy. The company is currently undergoing Chapter 11 reorganization and conducting clinical trials for various therapeutic applications.

4 investors

CSL is a biotechnology company that develops and manufactures plasma-derived and other therapies, including biotherapies for rare and serious diseases, vaccines, and treatments for iron deficiency and kidney disease. It operates through its CSL Behring, CSL Plasma, CSL Seqirus, and CSL Vifor businesses.

4 investors

Sava develops a wearable biosensor that continuously monitors multiple biomarkers (glucose, lactate, ketones, sodium, histamine, urea, alcohol, cortisol) in real-time, delivering health data to a mobile app for preventative health monitoring and chronic disease management.

4 investors

Scout Bio developed biotechnology therapies for pets, including a pipeline of monoclonal antibodies and gene therapy programs targeting chronic diseases in companion animals. The company was acquired by animal health firm Ceva in early 2024, and its work now operates as Ceva's biotechnology campus in Philadelphia.

4 investors

Prescription delivery platform connecting pharmacies, patients, and couriers to improve medication access and adherence

4 investors

SeaStar Medical develops the Selective Cytopheretic Device (SCD), a therapy that targets highly activated neutrophils and monocytes to neutralize the hyperinflammatory immune response in critically ill ICU patients facing conditions such as infection, trauma, or surgery. The device integrates with existing hemodialysis delivery systems and is aimed at reducing dependency on dialysis and time in the ICU.

4 investors

See-Mode develops software that applies AI and computational fluid dynamics to CT and MRI scans in order to estimate a patient's stroke risk. It is built to run within existing hospital imaging workflows, so clinicians can obtain these assessments from scans already acquired rather than ordering new imaging.

4 investors

Sequana Medical develops the alfapump system and DSR therapy for treating fluid overload in patients with conditions such as liver disease and heart failure. It is a publicly listed medical device company addressing unmet needs in the management of ascites and related conditions.

4 investors

Serna builds a platform to unlock the transcriptome as a drug target for drug discovery. The company integrates technology and biology to change drug discovery processes.

4 investors

Shiok Meats grows shrimp and other seafood through cellular agriculture, cultivating animal tissue in laboratories rather than harvesting from wild or farmed sources. The company produces meat with comparable taste, texture, and nutritional content to conventional seafood without animal farming.

4 investors

Sift Healthcare builds RevProtect, a predictive analytics platform that helps health systems anticipate reimbursement denials and optimize revenue cycle management before claims are submitted. The platform integrates clinical context and payer response patterns to deliver role-specific actions embedded in existing workflows.

4 investors

Siftwell is a healthcare technology company founded by former health plan operators and clinicians that applies data analytics and operational expertise to improve managed care organization (MCO) operations and member outcomes.

4 investors

SilverCloud by Amwell is a digital mental healthcare platform designed to provide mental health services to a broad audience. The company is committed to accessibility standards for disabled users.

4 investors

Cloud credentialing software for healthcare facilities and providers; acquired by AMN Healthcare in January 2019.

4 investors

Sirona Medical builds RadOS, a cloud-native platform that reimagines radiology practice in the AI age for physicians and radiology practices. The platform consolidates radiology workflows and leverages artificial intelligence to advance patient care delivery.

4 investors

Slope provides software to manage the biospecimen lifecycle in clinical trials, giving research sites, sponsors, CROs, and labs oversight of clinical sample inventory and real-time data. It serves the clinical research industry with a site-first platform connecting a network of NCI sites and academic medical centers.

4 investors

Wholsum Foods produces packaged snack cookies for children made with multigrains (whole wheat, jowar, oat) and natural ingredients, free from refined flours, palm oil, and synthetic additives. The company targets parents seeking healthier snacking options for kids.

4 investors

Sohar Health is a front-end revenue cycle management platform that uses technology and machine learning to automate insurance claims processing for healthcare providers. The company serves hospitals and medical practices seeking to improve claims accuracy and patient access to care.

4 investors

Spark Advisors provides a technology platform and back-office support for independent Medicare insurance brokers, covering quoting, enrollment, customer service, contracting, commissions, and reporting. It serves independent Medicare agencies and their downline agents, working with over 6,000 broker partners while letting agencies keep their own brands.

4 investors

SparrowUp provides personalized AI coaching to help individuals improve their physical skills and performance. The platform uses artificial intelligence to deliver customized training and guidance.

4 investors

Sparrow Pharmaceuticals is a clinical-stage biopharmaceutical company developing targeted therapies for cardiometabolic disease. Its lead program, clofutriben, is an HSD-1 inhibitor being evaluated in a Phase 2b trial for patients with inadequately controlled type 2 diabetes driven by elevated cortisol.

4 investors

SPR is a medical device company that develops the SPRINT Peripheral Nerve Stimulation (PNS) System, a non-opioid, non-surgical, minimally invasive treatment for acute and chronic pain. Its technology targets the peripheral nervous system to treat pain in the back, extremities, head, and neck for patients in pain management.

4 investors

Sprout is Canada's end-to-end family-building platform that connects users with fertility clinics, expert care, and support resources for fertility treatments, surrogacy, and adoption. The platform serves individuals and couples navigating the path to parenthood through integrated clinical guidance, educational resources, and community support.

4 investors

Stellar Sleep develops a digital solution for sleep management, founded by former insomniacs in collaboration with sleep experts.

4 investors