Healthtech Startups

Optum provides integrated healthcare services including doctor visits, mental health care, specialty care, and wellness services delivered through clinics, home, and online channels. The company also offers tools and technology to healthcare payers and providers to improve care efficiency, reduce costs, and support preventive care for over 120 million people across the U.S.

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Opyn provides a healthcare technology platform that unifies benefits, care navigation, virtual care, price transparency, provider intelligence, and service automation for health plan members, providers, and the administrative teams that support them. It aims to help members make informed care decisions while reducing manual work and costs for the teams operating health plans.

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OpZira develops wearable and diagnostic testing systems for the detection and monitoring of retinal and visual pathway diseases. The company serves eye care professionals and healthcare providers working with patients at risk for or diagnosed with ocular conditions.

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ORamaVR develops a platform for high-fidelity medical simulation training using extended reality technology, serving device companies, simulation centers, and hospitals globally. The company addresses the challenge of scaling medical education through spatial computing and computer graphics innovations.

1 investor

OraMetrix develops SureSmile, an orthodontic treatment system that uses digital scanning and personalized treatment plans to produce clear aligners and other teeth-straightening appliances. It serves dental and orthodontic practices, with doctors prescribing and delivering the treatment to patients.

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OraQ is an AI clinical decision support system for dental practices that applies risk intelligence to standardize exams, flag clinical risk early and support treatment planning. Based in Calgary, it works with dental practices across North America.

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Orb Health provides "Care Management as a Service," using remote, EMR-connected virtual contact centers staffed with licensed administrative and clinical agents to handle patient access, scheduling, and care coordination on behalf of providers. It serves health centers, hospitals, health systems, and unions across fee-for-service, capitated, and value-based care models.

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OrbiMed is a global investment firm that manages public equity, private equity, and private credit/royalty strategies focused on the healthcare industry.

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ORB Sport manufactures a custom-molded smart mouthguard with integrated sensors that track athletic performance and wellness metrics through a companion mobile app, designed for contact sport athletes.

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ORCHA provides digital health assurance and assessment services, validating health technologies against global standards for suppliers, health systems, and regulators worldwide.

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Orchestra Health provides software for streamlining preoperative care processes, helping surgical facilities reduce cancellations and improve patient outcomes. The platform serves surgeon offices and health systems performing orthopedic and spine procedures.

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Orchid provides contract manufacturing services for orthopedic medical devices to original equipment manufacturers and emerging companies in the medical device industry.

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Orchidia is a pharmaceutical company that completed a third investment round in 2026 with strategic international investors including SPE Capital, Proparco, EBRD, and BIO.

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Orcho offers a cross-system intelligence engine that connects claims, contracts, and payment data to predict which healthcare receivables will be paid and when. The platform is aimed at managing the financial risk in healthcare accounts receivable.

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Orenitram is a prescription oral medication containing treprostinil, indicated to treat pulmonary arterial hypertension (PAH) by slowing disease progression and improving exercise capacity in adults. The site is a drug information page covering safety, dosing, and side-effect details for patients and healthcare providers.

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Organ Recovery Systems develops organ preservation products and services, including machine perfusion technology for donor kidneys, for transplant programs and transplant professionals. The company supports over 400 transplant programs across 49 countries and also provides clinical and technical support services.

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Organogenesis is a regenerative medicine company that develops and commercializes products for the advanced wound care and surgical biologics markets, supplying clinicians and their patients. Its product portfolio includes tissue-based therapies such as Apligraf for wound care.

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Orgenesis provides decentralized manufacturing infrastructure for cell and gene therapies, enabling on-site processing of CGTs in regional centers through its POCare™ platform and OMPUL™ mobile processing units. The company aims to reduce costs, shorten development timelines, and improve patient access to personalized cell and gene therapies.

1 investor

ORIA is a Paris-based company, spun off from ENS Paris in 2022, that uses a proprietary mechanical microfluidic platform to extract intact, high-purity functional organelles at industrial scale. Its organelle products serve pharmaceutical companies, biotech firms, and academic institutions for drug discovery, disease modeling, and therapeutic research.

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Orienda International Hospital is one of Cambodia's larger hospitals providing medical care with a focus on patient satisfaction and modern facilities. The hospital operates with international standards and a team of medical specialists across diverse healthcare needs.

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Origami Therapeutics is a preclinical-stage biopharmaceutical company developing protein degrader therapeutics to treat neurodegenerative diseases, starting with Huntington's disease. The company uses a proprietary platform that harnesses the body's natural protein disposal system to degrade disease-causing proteins.

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OriGene develops and manufactures research and diagnostic products, including large-scale GMP antibody production, with R&D and research manufacturing operations. It serves the life sciences and biotech research market from facilities in the US and Germany.

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Origin Endoscopy has developed a multipurpose hydrogel designed for rapid bio-adhesion and submucosal injection applications in endoscopy. The technology targets surgical and medical procedure workflows that require biocompatible materials.

1 investor