Healthtech Startups

Spire Health provides continuous respiratory monitoring devices used by pulmonologists and patients to track lung disease. The company's sensors enable remote tracking of chronic respiratory conditions across the United States.

1 investor

Spirovant is a gene therapy company developing treatments for cystic fibrosis and other respiratory diseases, including viral vector-based therapies for airway epithelia. It is based in Philadelphia's Life Sciences Corridor.

1 investor

SpliSense develops antisense oligonucleotides (ASOs) — small synthetic RNA-binding molecules — designed using proprietary algorithms for therapeutic applications including splicing modulation and gene silencing. The company focuses on inhaled ASOs delivered directly to the lungs for treating pulmonary and obstructive lung diseases with minimal systemic exposure.

1 investor

Sporos Bioventures is a private biotechnology company that uses a portfolio approach to drug development in oncology, holding equity stakes in biopharma entities such as Tvardi Therapeutics and Sporos BioDiscovery. It is based in Houston, Texas.

1 investor

Sports Data Labs develops sensor-based technology platforms for capturing, analyzing, and distributing real-time human performance data from athletes, with applications in health monitoring, data monetization, and outcome prediction for sports organizations and professional athlete unions.

1 investor

Sports Impact Technologies builds a head impact monitoring system centered on a small sensor worn behind the ear with a medical-grade adhesive, paired with a charging case, mobile app for sideline alerts, and a web dashboard for tracking. The sport-agnostic system measures linear and rotational acceleration to help teams, coaches, physios, and researchers detect and manage head impacts in contact sports.

1 investor

SpotitEarly develops an at-home, non-invasive cancer pre-screening test that analyzes volatile organic compounds in exhaled breath samples using trained canines combined with its LUCID AI platform of biosensors and data analysis. The multi-cancer early-detection product is offered to consumers via online subscription and has been validated in clinical trials with healthcare institutions in Israel and the U.S.

1 investor

Sppare.me offers cryopreservation and storage of biological samples, keeping them in liquid-nitrogen tanks at an FDA-registered, state-licensed, CLIA-inspected lab. It operates through a partnership with the Diamond Institute for Infertility and Menopause, a US fertility center.

1 investor

Spring Loaded Technology develops bionic knee braces that enhance leg muscle power output for both therapeutic and athletic applications. The company serves people with mobility challenges seeking to restore function and reduce pain, as well as athletes looking to improve performance and reduce fatigue.

1 investor

1 investor

Sprint Bioscience is a pharmaceutical company developing oncology drug candidates aimed at new treatments for hard-to-treat cancers. It uses a fragment-based drug discovery approach and out-licenses its drug programs to global pharmaceutical companies during the preclinical phase.

1 investor

Sprout Pharmaceuticals is a pharmaceutical company focused on women's sexual health, known for developing Addyi (flibanserin), the first FDA-approved treatment for low libido in women. It serves patients and healthcare professionals with evidence-based treatments for female sexual dysfunction.

1 investor

1 investor

SPR develops the SPRINT PNS System, a peripheral nerve stimulation device for pain relief. The company serves patients and healthcare professionals in the medtech/pain management space and is now part of Medtronic.

1 investor

Spruce Capital Partners creates, advises, and invests in life sciences companies that make positive environmental impacts and improve human health and wellness.

1 investor

A biotech company dedicated to developing new vaccines, combining scientific expertise with commercial and operational capabilities.

1 investor

sqior provides a digital assistant for hospitals and clinics that understands clinical workflows and delivers relevant information or asks clarifying questions via mobile phone at the moment it is needed. The product is aimed at healthcare staff to support day-to-day operations in clinical settings.

1 investor

SQK develops a deep-technology stack combining quantum, AI, and high-performance computing, entering the market through medical imaging workflows before expanding into energy, manufacturing, and research applications. It offers products for pilots, API access, validation services, and enterprise simulation, targeting healthcare, industrial, and scientific environments.

1 investor

Squared Circles is a consumer health venture studio that partners with scientists and operators to conceive, launch, and scale consumer brands in health and longevity. It focuses on bioscience-grounded products aimed at the consumer wellness market.

1 investor

SQUID is a cloud-based medical device management platform for hospitals that integrates device data to optimize utilization, reduce costs, and free up nursing time.

1 investor

Squire is an AI tool that analyzes consultation conversations, documents, patient history, and dictations to generate medical reports, forms, and codings in standards like FHIR, SNOMED CT, and ICD-10. It targets healthcare professionals and providers, offering a developer integration and a platform to customize output templates and monitor usage and accuracy.

1 investor

Oops LOVE offers online telemedicine for men's health conditions such as ED and AGA (hair loss), with consultations and prescriptions handled through LINE. The service is aimed at consumers in Japan.

1 investor

Srotas Health develops an AI platform to match patients with suitable clinical trials and help trial sites and sponsors manage recruitment. The company serves patients, clinical research sites, and pharmaceutical sponsors in the healthcare and clinical trials industry.

1 investor

SRS Medical develops diagnostic and therapeutic technologies for urologic care, specifically for men with Benign Prostate Hyperplasia, using bladder function assessment to guide clinical treatment decisions.

1 investor