Healthtech Startups

Neurodegenerative disease drug discovery correcting misfolded-protein cellular pathologies. IPO as YMTX.

4 investors

Zaya Care provides maternal care in the United States using a European-style, insurance-covered model, working with payers to make care affordable and accessible. It focuses on human-centered care for expecting and new mothers.

4 investors

Zeit Medical develops a wearable headband with AI-powered sensors that detects strokes in real time and automatically alerts emergency services, targeting patients at high risk for stroke who may be asleep or unable to call for help themselves.

4 investors

Zenyum manufactures and sells direct-to-consumer oral care products including invisible braces, electric toothbrushes, teeth whitening kits, water flossers, and toothpaste.

4 investors

Zeto develops improved electroencephalography technology for diagnosing epilepsy and other neurological conditions. The company serves physicians and medical institutions seeking advanced EEG diagnostic tools.

4 investors

Fabric (formerly Zipnosis) provides an end-to-end care access platform and virtual care services that combine conversational AI and physician-built clinical logic to automate patient intake, triage, routing, and clinical documentation. It serves health systems, health plans, employers, and brokers to reduce costs and improve care access and experiences.

4 investors

Zivian Health builds compliance infrastructure and workforce management software for healthcare providers, nurses practitioners, and physician assistants operating across multiple states or remotely. The platform helps healthcare organizations manage clinical collaboration, regulatory compliance, and team coordination at scale.

4 investors

ZOE is a digital health company that uses continuous glucose monitoring and personalized nutrition science to help users make food choices aligned with their individual biology and optimize their metabolic health.

4 investors

Zuub provides dental insurance verification through direct payer connections and a REST API, delivering standardized eligibility, benefits, and coverage data. It serves dental technology platforms, practice management and billing systems, and multi-location DSOs to support real-time verification, accurate patient estimates, and clean claims.

4 investors

Portrai analyzes spatial transcriptomics data together with tissue staining images using AI to generate insights for drug development, supporting drug licensing asset evaluation and drug repurposing. The company applies spatial biology data to innovate the pharmaceutical R&D process.

4 investors

LPIXEL develops AI-based image analysis products for the life sciences and healthcare fields, including medical image diagnostic support technology and drug discovery image analysis tools. Its offerings are used by medical institutions, with clinical deployment across hundreds of facilities in Japan.

4 investors

Kringle Pharma develops and manufactures HGF protein-based pharmaceuticals for treating conditions including spinal cord injury, ALS, and vocal cord scarring. The company is a spin-out of Osaka University and Keio University focused on drug development in the biotech sector.

4 investors

Toregem Biopharma is a Kyoto University spin-off developing a tooth-regeneration drug based on a humanized anti-USAG-1 antibody that aims to regrow teeth with a single injection. It initially targets patients with congenital tooth agenesis (a rare genetic condition) and ultimately aims to treat tooth loss from decay or periodontal disease.

4 investors

Rege Nephro develops regenerative medicine therapies for kidney disease, focusing on nephron progenitor cell research and differentiation from iPS cells. The company aims to commercialize treatments for patients with kidney disorders and reduce reliance on dialysis and transplantation.

4 investors

AI Medical Service Inc. develops AI systems that support image-based diagnosis of endoscopy, primarily for detecting gastrointestinal cancers such as stomach and esophageal cancer. The Japan-based medical device company sells its gastroAI product line to endoscopy and gastroenterology settings, with operations expanding to the US and Southeast Asia.

4 investors

Buzzreach is a Japanese startup that builds SaaS platforms connecting pharmaceutical companies and medical institutions with patients to support clinical trials and post-launch marketing. It promotes a "DRO" (Digital Research Organization) model using patient-matching via electronic medical records, AI-generated trial documents, decentralized clinical trials, and a patient-centric social network called "miilike."

4 investors

CogSmart is a university-originated company applying brain medicine and artificial intelligence to brain health, with a flagship service, BrainSuite, that uses AI to visualize the brain as a screening experience meant to prompt lifestyle changes. It aims to support lifelong brain health and well-being for individuals.

4 investors

PURMX Therapeutics develops nucleic acid medicines as anti-cancer drugs based on microRNA research and the concept of an "ageing switch" to induce ageing in cancer cells. The Japanese pharmaceutical venture handles drug development functions including non-clinical research, clinical development, CMC, and regulatory affairs.

4 investors

RABO provides pet care services and technology solutions for cat owners and pet service professionals in Japan. The company was founded on Cat Day (February 22, 2018) by a team with expertise in bioscience research and product development.

4 investors

Biophilia manufactures fresh pet food for dogs and cats, positioning itself as a pet wellness company that delivers nutrition and health through daily meals. The company serves pet owners in Japan and operates a Hong Kong office.

4 investors

1Cell.ai develops an AI-driven, single-cell multi-omics and ctDNA platform for high-resolution tumor profiling, non-invasive cancer diagnostics, and biomarker discovery. It serves clinicians, oncology researchers, and biopharma partners across cancer care and drug development.

3 investors

1Huddle is an AI-powered employee engagement and performance platform that uses gamified learning experiences to help organizations build culture, onboard staff, and upskill teams. It serves enterprise clients across industries with customizable branded games, performance tracking, and talent development tools.

3 investors

4D Surgical develops imaging technology for image-guided surgical procedures. The company serves surgical teams and healthcare institutions seeking to improve surgical precision and outcomes.

3 investors

A platform that connects people seeking emotional support with trained volunteer listeners via anonymous one-on-one chat, allowing users to discuss personal concerns without judgment or advice-giving.

3 investors