Hardware Startups

Critical Frequency Design delivers mission-critical engineering and manufacturing solutions for defense acquisition projects, leveraging deep expertise in supply chain and program management. The company serves defense agencies and prime contractors from its base in Florida's Space Coast region.

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Crossover is a stealth-mode medical device company developing two Class II (510(k) pathway) implant systems for ankle fracture fixation, specifically fibular nailing and syndesmosis repair. It targets the US lower-extremity trauma fixation market and is building the devices with an acquisition-oriented strategy for strategic orthopedic partners and surgeon advisors.

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CSW Industrials is a diversified industrial company operating across three segments—Contractor Solutions, Specialized Reliability Solutions, and Engineered Building Solutions—producing niche value-added products under brands such as RectorSeal, TRUaire, Whitmore, and Jet-Lube. It serves end markets including HVAC/R, plumbing, electrical, general industrial, architecturally-specified building products, energy, mining, and rail transportation.

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Cyber Advanced Technology (CAT) builds an alternative network and computing infrastructure called OT-OCN, along with hardware appliances, an AI framework (CAT AI-ONE), the WebChain blockchain, and cybersecurity systems for smart cities, national defense, energy, and financial infrastructure. Its products aim to provide immune-layer security, real-time deterministic processing, and DePIN-ready sovereign infrastructure.

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Cypris Medical develops minimally-invasive medical devices and treatments designed specifically for plastic surgeons to deliver results comparable to traditional surgery with shorter recovery times. The company combines medical device expertise with input from practicing surgeons to address unmet needs in the plastic surgery market.

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DaVinci Lock Store sells self-storage access and security products, including combination locks with QR code and text-to-release features, gate access technology (G.O.A.T.), a tenant management tool (Tenant Connect), and accessories like lock drop boxes. Its products are aimed at self-storage facility operators to manage gate access and tenant lock operations.

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Davy builds, owns, and operates modular on-site hydrogen electrolyzer units (40-ft skids) that produce hydrogen locally for fueling forklift fleets, yard equipment, and industrial process needs. It serves enterprise operations such as retail distribution centers, e-commerce fulfillment networks, home-improvement logistics hubs, and heavy industry including metalworking and power-generation utilities.

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Decision Sciences Corp develops imaging technology for port-of-entry security that scans cargo to distinguish legitimate shipments from concealed contraband and detect hidden threats.

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Diagnostic Biochips develops multichannel neural probes for extracellular recording in electrophysiology research, along with cloud-based software for spike sorting and analysis. It serves neuroscience researchers studying the brain at the neural network level.

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Diality is a medical device company developing a home hemodialysis machine and related solutions for patients with kidney disease, aimed at supporting new decentralized kidney-care models. The Series-B company serves the dialysis and nephrology market and is based in Irvine, California.

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Diametryx develops color-changing micro- and nano-scale particles that can be deployed in ink or film, using new actuation mechanisms and compositions. The company works in advanced materials, offering particles capable of rapid color changes across a broad color palette.

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DIANT develops proprietary Jet technology and continuous, closed manufacturing systems for producing nanoparticles and lipid nanoparticles (LNPs), and offers R&D through manufacturing services. Its systems serve customers making nanoparticle products for pharmaceuticals, nutraceuticals, food, beverage, and cosmetics.

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Digital Ally manufactures and sells video surveillance solutions—including body cameras, vehicle systems, and IP surveillance—along with related software and storage, primarily for law enforcement agencies, commercial fleet companies, and event security teams.

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Dilon Technologies is a medical device manufacturer that develops surgical instruments and diagnostic tools for healthcare practitioners, including gamma probes for lymphatic mapping, margin assessment devices for breast cancer surgery, and video laryngoscopes.

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Dimer Instruments develops high-performance scientific instruments for biopharmaceutical analysis, using light scattering and biophysical characterization technologies to accelerate drug development processes. The company serves pharmaceutical researchers and drug development teams.

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DIMIDE designs and builds the 1/4 Series Clamp, a modular, impact-rated clamp intended for use with 1/4-inch impact drivers to deliver clamping force with one hand. The clamp uses interchangeable shoes for applications such as welding grounds and pipe clamping, serving tradespeople and industrial users.

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Dino Don Inc. designs and builds large, anatomically accurate robotic dinosaurs for zoos and museums worldwide. The company is led by Jurassic Park advisor "Dino" Don Lessem.

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DJ MicroLaminates develops thin and thick dry film photoresist materials that let semiconductor and electronics device manufacturers build smaller electronic devices, including applications in MEMS, wafer level packaging, and high aspect ratio structures. It serves universities, research centers, consumer and medical device makers, and chipmakers as a supplier of advanced photosensitive materials.

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Double Helix Optics develops 3D imaging and sensing technology for scientific microscopy, based on its engineered point spread function (ePSF) and Nobel Prize-winning super-resolution methods. Its SPINDLE modules, phase masks, and 3DTRAX software attach to existing microscopes to capture instantaneous nanoscale 3D data for researchers in spatial biology and life sciences.

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Dragonfly Endoscopy develops a fully rotatable 360° pancreaticobiliary endoscope with refined optics, precision control, and therapeutic capabilities for cholangiopancreatoscopy. The company makes medical devices for treating pancreaticobiliary disease and has received FDA 510(k) clearance for its scope.

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DroneShield develops AI-powered hardware and software solutions to detect, track, and defeat unmanned drone threats for defense and security applications. The company is publicly listed on the Australian Securities Exchange and specializes exclusively in counter-UAS technology.

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Droplet Measurement Technologies designs and manufactures scientific instruments and airborne probes for researchers studying atmospheric and cloud physics across global research institutions.

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Dura-Line manufactures high-density polyethylene (HDPE) conduit and protective pathways for fiber optic cables used in telecommunications and broadband infrastructure. The company serves telecommunications operators, internet service providers, and infrastructure developers globally seeking to expand high-speed broadband connectivity in developed and developing markets.

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Dynocardia develops ViTrack, a wearable and connected platform for continuous monitoring of blood pressure and other vital heart and lung functions. The technology targets applications across hospitals, clinical practice, remote patient monitoring, and consumer wellness.

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