Hard Tech Startups

Starcloud is a deep-tech company building large-scale data center infrastructure designed to operate in space. Its team comes from aerospace and cloud-hardware backgrounds including SpaceX, Amazon's Leo satellite constellation, Microsoft Azure, and fusion energy programs.

34 investors

AstroForge is a space mining company that extracts platinum group metals and other valuable materials from asteroids to integrate into Earth's supply chains. The company aims to reduce reliance on terrestrial mining by developing commercial deep-space resource extraction missions.

22 investors

Albedo develops a flight-proven platform for Very Low Earth Orbit operations, providing satellite-based insights and connectivity services for national security and critical infrastructure systems. The company focuses on making space infrastructure operationally viable and resilient.

21 investors

Andromeda Surgical develops an AI-guided surgical platform that provides GPS-like navigation and autonomous task capabilities to surgeons, starting with endourology procedures. The platform integrates with existing surgical tools to assist interventional surgeons in performing procedures with enhanced precision and reduced training requirements.

20 investors

Hubble has created a Bluetooth connection to space and is building a global, battery-efficient, and cost-effective network using satellite technology.

18 investors

Inversion develops spacecraft and systems to establish Low-Earth Orbit as an on-demand logistics network for rapid global transportation and defense applications. The company manufactures reentry vehicles and related hardware to enable cargo transportation across Earth via space.

18 investors

Wyvern develops high-resolution hyperspectral imaging satellites and delivers satellite-based earth observation data for model-based predictions. The company operates a satellite constellation in the space technology and remote sensing sector.

15 investors

Atomic Industries uses artificial intelligence and custom software to design plastic molds for manufacturing, enabling faster production of injection-molded parts for customers.

13 investors

Conductor develops AI algorithms and control software for quantum computing, helping researchers and engineers optimize qubit architectures and scaling in semiconductor-based quantum systems.

13 investors

A materials company focused on nanotechnology for renewable energy and clean technology applications, manufacturing various classes of materials to address problems in those fields.

12 investors

Mindstate Design Labs is a clinical-stage drug development company that uses AI to map the biological basis of emotion and cognition, synthesizing psychedelic phenomenology and biochemical data to design pharmaceutical compounds that induce specific therapeutic emotional and cognitive states for mental health treatment.

12 investors

1849 bio engineers microorganisms to make metal extraction from low-grade copper and gold ores economically viable for mining operations. The company applies advanced bioengineering techniques to develop microbes capable of processing ore types that existing biomining processes cannot handle, targeting the hundreds of billions of dollars in copper currently considered uneconomical to extract.

11 investors

Luminate develops medical device technology to address chemotherapy side effects, particularly hair loss and peripheral neuropathy, for oncology patients and healthcare providers. The company is advancing clinical-stage devices while supporting cancer patients, clinicians, and health systems.

10 investors

Polymath develops core autonomy software for off-highway robots, providing modular planning, safety, and infrastructure tools to help robotics programs accelerate development and deployment. The platform serves original equipment manufacturers, fleet operators, and government programs.

10 investors

AirMyne develops engineered carbon removal technology that captures CO2 directly from the air, as well as at point-of-emissions, to help corporations and governments manage and reduce their CO2 emissions. Its platform is designed for high uptime and durable, scalable carbon removal capacity.

9 investors

Atum Works develops scalable 3D lithography technology capable of printing metal structures with submicron resolution for advanced manufacturing applications.

9 investors

Ethos Space develops technology to build and operate spaceports and infrastructure on the Moon using in-situ lunar resources, including construction material (Durandal), onsite propellant production (Prometheus), and materials for space-based data centers. The company also publishes research reports on lunar and planetary resources such as silicon, water, critical minerals, and helium-3.

9 investors

Humane Genomics develops oncolytic viral therapies designed to selectively target and kill cancer cells using engineered RNA viruses, particularly Vesicular Stomatitis Virus. The company leverages a computational platform for viral genome design and engineering to create cancer treatments with improved safety, efficacy, and manufacturing efficiency.

9 investors

Lightberry develops AI software that enables robots to understand and respond to voice commands, allowing non-technical users to control and program robots through conversation rather than traditional coding.

9 investors

Siphox Health develops early diagnostic testing technology to detect and manage chronic diseases at home, delivered as a painless 5-minute test that enables frequent monitoring. The company targets the U.S. healthcare system to reduce the health and economic burden of chronic disease.

9 investors

Atomic Alchemy builds privately-owned nuclear reactors dedicated to radioisotope production, including Molybdenum-99 used in most nuclear medicine procedures. It aims to supply radiopharmaceutical materials for diagnostic imaging, biological tracers, and cancer treatments.

8 investors

Cascade Space develops software tools and infrastructure for designing, building, testing, and operating spacecraft communication systems. The company serves aerospace and space companies seeking to accelerate development with reduced team requirements.

8 investors

Impossible Metals builds underwater robotic vehicles to collect critical metals from the seabed for clean energy applications, with a focus on sustainable and environmentally responsible extraction practices.

8 investors

Odys designs and builds long-range, hybrid-electric VTOL aircraft for defense, logistics, and civil applications. The company's aircraft use flap-based thrust vectoring architecture and serve missions including tactical cargo transport, emergency medical evacuation, and defense operations.

8 investors