Digital Health Startups

Semalytix builds Project Atlas, an agentic AI platform that converts multilingual patient experience data into continuous intelligence for pharmaceutical medical, commercial, HEOR and pharmacovigilance teams. It monitors patient voice across 26 languages and 144 countries, offering modules for pharmacovigilance, respiratory-outbreak detection, and treatment adherence.

2 investors

Sensai is a fitness and wellness platform that publishes health and training guidance for active people and athletes, including topics such as nutrition and heart health.

2 investors

Senscio operates an Intelligent Care Continuity System that monitors clinically complex populations between medical encounters to detect health changes early and coordinate interventions. The platform combines continuous health monitoring and AI-driven prioritization with selective human clinical oversight to reduce avoidable hospitalizations and ED visits for health plans, health systems, and medical groups.

2 investors

Sensorum provides home-based passive sensor technology and integrated clinical services to detect early signs of health decline in older adults with chronic conditions. The platform enables 24/7 monitoring without wearables or cameras, with nurse-led clinical interventions to prevent hospital admissions.

2 investors

SeqOne provides a clinical genomics analysis platform for germline and somatic variant interpretation across panels, exomes, and genomes, supporting short and long-read sequencing. It offers tools such as a DiagAI variant-prioritization score and an automated data pipeline (SeqOne Flow), serving diagnostic labs and clinical genomics teams with a CE-IVD certified in vitro diagnostic medical device.

2 investors

SequelCare offers a measurement-based mental health therapy platform for clinicians and multidisciplinary care teams to plan treatment, share data in real time, and coordinate care with patients and external providers. The platform focuses on evidence-based therapy workflows, patient engagement, and improving clinical and financial outcomes for mental healthcare practices.

2 investors

Serenity Connect provides a voice-first platform with automated workflows and real-time communications designed for older adults and their care networks. It connects senior living, home health, hospice, and pharmacy providers with families through features like voice access to information, video calls, and e-forms.

2 investors

Serent provides managed revenue cycle management (RCM) services for home health agencies, combining board-certified home health coders with proprietary AI to handle ICD-10 coding, OASIS review, Plan of Care review, and coding audits. The company aims to improve coding accuracy, reduce denials, and increase reimbursement for home health providers.

2 investors

Settld is a notification platform that helps bereaved individuals and professionals notify banks, utilities, insurers, pension providers, and other service companies of a death in a single place, tracking progress throughout the process. The service operates in the United Kingdom.

2 investors

Sevaro is a healthcare technology company focused on advancing stroke care through clinical trials, artificial intelligence, medical informatics, and telemedicine solutions.

2 investors

Sevelyn offers online access to licensed providers who share the Spanish language and Latino culture, connecting Latino clients with education and professional support at rates it states are a quarter of traditional prices. The service is delivered remotely through an encrypted platform focused on privacy and anonymity.

2 investors

Shamiri operates a youth mental health care model that uses trained lay and semi-professional providers to deliver brief interventions, backed by software (shamiriOS and shamiriAI) that lets governments and partners run the program themselves. It focuses on reaching young people in Africa and the Global South at low cost.

2 investors

Sharecare operates a digital health platform that helps employees, health plan members, and patients manage their health, navigate care, and optimize benefits. Its offerings include health tracking, evidence-based digital therapeutics, personalized care navigation and advocacy, and in-home caregiving services via CareLinx.

2 investors

ShareWell offers online peer support groups, private 1-on-1 sessions with trained peer specialists, and skill-building workshops for people facing mental health and life challenges. It provides free live moderated group sessions across 150+ topics with paid membership options for unlimited groups and private support.

2 investors

Shen AI provides camera-based, contactless health monitoring that uses remote photoplethysmography (rPPG) and AI to measure 30+ health markers—including blood pressure, heart rate, HRV, and BMI—through a face scan in about 30 seconds. It offers an SDK with on-device edge processing and FHIR API integration for healthcare, telehealth, remote patient monitoring, corporate wellness, fitness, and insurance providers.

2 investors

ShiftMed operates an on-demand healthcare staffing platform that connects hospitals, health systems, and long-term care facilities with credentialed nurses (CNAs, LPNs, RNs) to fill shifts and manage their workforce. It integrates via API with workforce management systems and offers worker benefits such as transportation, insurance, and education.

2 investors

Shimmer provides coaching, community, and digital tools designed specifically for people with ADHD, combining expert guidance with peer support to help them reach their potential. The platform serves neurodivergent individuals seeking ADHD-specific support outside traditional mental health systems.

2 investors

Sifio Health builds a digital platform, SurgiTwin, that uses AI and historical data to predict surgical case durations and analyze perioperative workflows for hospital surgical teams and operating rooms. Its analytics and automation tools aim to improve operating room utilization, scheduling accuracy, and data quality for surgical centers.

2 investors

Sign on Tab develops digital document management software with legally binding digital signatures and biometric data capture, offering products such as digital templates, a virtual printer, cloud storage, and API integrations. A division of ITO Group serving over 220 business customers, its largest client base is in the healthcare sector, where it supports patient onboarding and data management.

2 investors

Signal Fusion provides AI-powered behavioral and voice analytics that convert human signals into predictive intelligence for safety, readiness, and performance monitoring in high-stakes industries. The platform identifies subtle human-state changes like stress and coordination drift to prevent accidents and improve operational integrity across maritime, transportation, construction, mining, manufacturing, healthcare, energy, and utilities sectors.

2 investors

Signant Health provides eClinical technology and services for clinical trial data collection, including electronic data capture, patient and site data solutions, and scientific and operational support. It serves pharmaceutical sponsors and CROs running global clinical trials to generate high-quality data for trial decisions and regulatory submissions.

2 investors

Signatur Biosciences develops molecular diagnostic solutions using qPCR technology for in vitro diagnostics, targeting clinical and laboratory markets. The company aims to deliver advanced diagnostics on widely available instrumentation to expand access to cutting-edge healthcare globally.

2 investors

SilverRide is a licensed Transportation Network Company providing ADA-compliant assisted transportation for older adults and people with disabilities, using its own technology platform and a credentialed driver network. It operates through paratransit partnerships with transit agencies, contract services for PACE and healthcare organizations, and direct booking for riders and families.

2 investors

Simbie AI builds healthcare workflow management software for clinical practices, automating scheduling and documentation to reduce administrative burden on providers and improve patient care.

2 investors