Digital Health Startups

Altay Therapeutics develops small molecule inhibitors targeting transcription factors to treat serious diseases including facioscapulohumeral muscular dystrophy and cancer. The company's pipeline includes oral drug candidates designed as first- or best-in-class therapeutics for oncology and inflammatory conditions.

4 investors

Altira provides AI-powered patient engagement and guidance to healthcare systems, combining clinical expertise with adaptive artificial intelligence to improve health outcomes and reduce unnecessary care utilization. The platform serves clinicians and healthcare organizations delivering value-based care.

4 investors

Altis Labs provides a web-based platform that applies AI models to medical imaging data to generate reproducible predictions and quantifications for clinical trials. It serves biopharma and clinical trial teams, helping them detect treatment effects, inform trial design and go/no-go decisions, and generate evidence for reimbursement.

4 investors

Altris AI develops artificial intelligence software for analyzing optical coherence tomography (OCT) scans in eye care, serving ophthalmologists and optometrists for diagnostic support and patient assessment. The company's platform helps detect retinal conditions and glaucoma risk, and is installed in over 500 optometry centers and clinics globally.

4 investors

AltrixBio develops AJN003, a once-daily oral therapy that forms a temporary, non-systemic coating on the stomach and upper gastrointestinal tract to alter nutrient sensing and trigger metabolic and hormonal responses. The platform targets type 2 diabetes and obesity, with potential applications in oral drug delivery.

4 investors

Alyve Health operates a healthcare and insurance platform organized around seven wellness pillars—motivation, movement, mental health, nutrition, habits, sleep, and financial wellness—offering health plans, preventive care, and access to trusted providers. Based in India, it serves consumers and enterprise/employer groups, including gig workers, with integrated health coverage.

4 investors

Amae Health provides in-person, coordinated care for people living with severe mental illness (SMI), combining clinical treatment with a precision medicine platform built on longitudinal, data-driven insights. It works with institutions such as Cedars-Sinai, NewYork-Presbyterian, and Massachusetts General Hospital to improve how SMI is diagnosed and treated.

4 investors

American Gene Technologies develops gene therapy treatments for serious diseases including HIV, phenylketonuria, and liver cancer, using a proprietary platform approach designed to accelerate drug development and reduce costs.

4 investors

AngelQ is an AI-powered educational app designed for children that transforms screen time into personalized learning through voice-activated Q&A, age-appropriate content, and parental controls. The platform serves families seeking safe, engaging learning tools with built-in research literacy and family engagement features.

4 investors

Anima is a healthcare platform that combines online consultation with productivity tools, featuring EHR integration, advanced analytics, and AI-powered document processing to streamline primary care workflows and improve patient outcomes.

4 investors

Antidote Health provides virtual primary care through board-certified physicians who deliver telehealth services covering preventive care, chronic disease management, urgent care, and specialized support including women's health and pediatric care.

4 investors

Apella provides real-time operating room monitoring and predictive analytics through computer vision and AI integration with EHR systems, helping surgical teams detect delays, optimize scheduling, and improve OR efficiency. The platform serves healthcare providers and surgical operations by automating event documentation and enabling data-driven decisions across the perioperative team.

4 investors

Aprexis offers a platform for medication therapy management (MTM) and customizable clinical programs covering lifestyle medicine and disease management, using AI-driven patient stratification, a patient-facing mobile app, and EHR interoperability. It serves pharmacists, health plans, and Medicaid/Medicare programs, with tools addressing medication adherence, health equity, and quality metrics such as HEDIS and Stars.

4 investors

Arbor develops programmable DNA editors for genetic medicine, aiming to enable functional cures for patients by addressing genetic diseases through bespoke gene editing approaches. The company is developing a portfolio of DNA editing technologies capable of targeting over 90% of the human genome for therapeutic applications.

4 investors

Artisight builds an AI platform that uses computer vision and operational intelligence to improve hospital workflows and clinician efficiency. The platform connects to existing hospital systems and cameras to help healthcare organizations optimize operational performance, quality metrics, and workforce sustainability.

4 investors

Aspect provides personalized health management for women by combining data from wearables, glucose monitors, at-home medical tests, and doctor assessments with AI analysis and coaching from healthcare professionals. The platform focuses on chronic condition management with particular attention to women's health issues including PCOS, endometriosis, and menopause.

4 investors

Aster provides patient management software and agentic AI voice tools for healthcare providers. The company was acquired by Elation.

4 investors

Astrivax Therapeutics is a clinical-stage biopharmaceutical company developing immunotherapies to treat virus-driven cancers, particularly HPV16-associated cancers like cervical and head and neck cancer. The company's Launch-iT platform generates durable T-cell responses against virus-infected cells and is advancing toward clinical proof-of-concept.

4 investors

Autonomize builds an AI operating layer for healthcare enterprises that structures unstructured data, grounds decisions in clinical and policy evidence, and orchestrates workflows through healthcare-native AI agents working alongside human experts. The platform transforms healthcare operations to be faster, more accurate, and continuously learning for payers and providers.

4 investors

AvaSure provides AI-powered virtual care technology for hospitals and health systems, aimed at protecting staff and improving patient safety and outcomes. Its solutions address the nursing workforce shortage through virtual nursing and video monitoring models.

4 investors

Avela Health provides virtual autism evaluations and therapy for children, teens, young adults, and their families, with services delivered by Master's or doctoral-level clinicians via video. It offers age-specific therapy programs, group support, school coordination, and specialty care, primarily serving families in New Jersey, Pennsylvania, and South Carolina.

4 investors

Avenda Health develops Unfold AI, deep learning software that maps a patient's prostate cancer in 3D to give physicians visualization and information for treatment planning. The company serves urologists and physicians treating prostate cancer patients in the medical device and healthcare space.

4 investors

Aviary Health provides virtual and hybrid clinical programs — including cardiac rehabilitation, pulmonary rehabilitation, and chronic care management — combining AI-powered workflows with clinical teams. It serves hospitals and health systems, delivering end-to-end support for complex service lines.

4 investors

Biotechnology company developing immunomodulators using a HALOS nanotechnology platform for chronic inflammation.

4 investors