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AltrixBio

Wilmington, US · 4 known investors

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AltrixBio develops AJN003, a non-systemic, once-daily oral therapy for type 2 diabetes and related metabolic conditions that transiently coats the stomach and upper intestine to shift nutrient sensing and trigger a metabolic reset similar to bariatric surgery. The drug targets glycemic control and weight loss and is positioned as a complement or alternative to incretin-based (GLP-1) treatments, with potential applications in broader cardiometabolic diseases.

Founders & leadership

AT
Ali TavakkoliCo-founder
NBNancy Briefs
Nancy BriefsExecutive Chair of the Board & FounderNancy Briefs is Executive Chair and Founder of AltrixBio, a biotech company developing an oral therapy for type 2 diabetes and metabolic conditions. She brings experience as a board member and former CEO in digital health, medical devices, and pharmaceuticals, with a track record of raising capital and achieving multiple exits across portfolio companies.
JKJeff Karp
Jeff KarpCo-founder

Board

JB
John BrooksBoard director

Investors · 4

Reported raises · per SEC filings

Form D private placements

$7.8M disclosed across 2 rounds · 2019–2025

▶$1.2MraisedJun 2025 · 20 investors · Pharmaceuticals
Rule 506(c)
Officers, directors & promoters on the filing
  • John BrooksDirector
  • Jeffrey KarpDirector
  • Ali TavakkoliDirector
  • Nancy BriefsExecutive Officer, Director
Offering amount
$10M
Amount sold
$1.2M
Minimum investment
$10K
Finders' fees
$250K
Proceeds to insiders
$75K
First sale
Apr 2025
Incorporated
Corporation, Delaware
Federal exemptions
04, 06c, 4a5
Full filing on SEC EDGAR ↗
▶$6.6MraisedJun 2025 · 50 investors · Pharmaceuticals
Rule 506(c)
Officers, directors & promoters on the filing
  • Jeffrey KarpDirector
  • Nancy BriefsExecutive Officer, Director
  • Ali TavakkoliDirector
  • John BrooksDirector
Offering amount
$6.6M
Amount sold
$6.6M
Minimum investment
$10K
First sale
Mar 2019
Incorporated
Corporation, Delaware
Federal exemptions
04, 06c, 4a5
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

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In the news

Frequently asked questions

What does AltrixBio do?
AltrixBio develops AJN003, a non-systemic, once-daily oral therapy for type 2 diabetes and related metabolic conditions that transiently coats the stomach and upper intestine to shift nutrient sensing and trigger a metabolic reset similar to bariatric surgery. The drug targets glycemic control and weight loss and is positioned as a complement or alternative to incretin-based (GLP-1) treatments, with potential applications in broader cardiometabolic diseases.
Who founded AltrixBio?
AltrixBio was founded by Ali Tavakkoli, Nancy Briefs, Jeff Karp.
Who are AltrixBio's investors?
AltrixBio's investors include Service Provider Capital, Taihill Venture, Walnut Venture Associates, xfactor ventures.
How much funding has AltrixBio raised?
AltrixBio has disclosed $7.8M raised across 2 rounds.
Where is AltrixBio headquartered?
AltrixBio is headquartered in Wilmington, US.