Digital Health Startups

Reframe is a digital habit-change program that helps users reduce or eliminate alcohol consumption through science-based methods. The app provides personalized information and tools for individuals seeking to change their relationship with alcohol.

5 investors

Regard builds healthcare technology that makes patient medical records fully accessible to clinicians at the point of care, enabling more informed diagnosis and documentation. The company serves physicians and healthcare systems seeking to improve clinical decision-making and patient outcomes.

5 investors

Remedy Meds offers personalized medical weight loss treatment using compounded GLP-1 medications (semaglutide and tirzepatide) paired with clinician-led care and support delivered directly to patients. The service targets individuals seeking prescription-based weight loss solutions with ongoing medical supervision and community support.

5 investors

RetinaLogik makes the RVF200, a portable visual field testing headset that runs core eye exams including visual field, color vision, and acuity for use in ophthalmology and optometry clinics. A University of Calgary spin-out, its technology applies deep learning to glaucoma detection and is used by eye care providers in multiple countries.

5 investors

Rhythm Therapeutics develops precision medicines for rare neuroendocrine diseases, particularly those affecting the melanocortin-4 receptor pathway. The company's lead product, IMCIVREE (setmelanotide), is FDA-approved to treat severe obesity caused by genetic impairments in the hypothalamus.

5 investors

Risa Labs provides automated prior authorization and revenue-cycle workflows for oncology practices, handling Part B and Part D drug authorizations, eligibility and benefit verification, claims status tracking, and denial management. Its platform integrates with EHRs and payer portals, APIs, and e-fax to execute payer-related administrative tasks with configurable, rules-driven workflows.

5 investors

Rocket Pharmaceuticals develops gene therapies to treat patients with rare genetic diseases, focusing on cardiovascular and hematologic disorders. The company creates potentially curative treatments at the genetic level for inherited and rare diseases.

5 investors

Rx Redefined provides a platform and management services for DMEPOS (durable medical equipment, prosthetics, orthotics, and supplies) ordering, handling revenue cycle processes, compliance checks, and audit processing for physicians. It integrates with existing EMR systems and reviews billing requirements, patient eligibility, and regulatory adherence for each physician order.

5 investors

RxAll uses testing technology to detect counterfeit and substandard medicines, helping healthcare companies, pharmacies, and patients access verified high-quality drugs. It also offers financing and sales software for pharmacies and wholesalers, with a focus on Africa.

5 investors

RxDiet provides AI-powered personalized nutrition programs with fresh ingredient delivery to help health plans and at-risk populations manage chronic diseases like diabetes and heart disease. The platform combines medically tailored meal delivery, digital behavioral guidance, and community support to improve treatment adherence and reduce healthcare costs.

5 investors

Samaritan offers financial and social support programs aimed at keeping high-need, vulnerable patients engaged in their healthcare, with the goal of improving health outcomes and lowering care costs. It targets healthcare payers and providers managing populations tracked by metrics such as HEDIS compliance and emergency department utilization.

5 investors

Sana provides health plans and benefits administration services for small businesses, helping employers manage healthcare costs for their teams. The company focuses on delivering affordable coverage and a seamless care experience to members.

5 investors

Sano provides a platform combining genetic testing, patient recruitment, and engagement tools for precision medicine clinical trials. The platform helps research teams enroll participants and manage operations more efficiently in precision medicine studies.

5 investors

Scenic Biotech develops modifier therapy, a genetic medicine approach that targets secondary functions in the genome to neutralize the impact of disease-causing mutations. The company uses its proprietary Cell-seq platform to develop small molecule programs for genetic disorders.

5 investors

Science37 operates a decentralized clinical trial platform supported by a network of medical directors across specialties including cardiology, neurology, psychiatry, pediatrics, and internal medicine. The company serves the clinical research and pharmaceutical industry.

5 investors

She's well offers a fertility subscription that bundles egg freezing and fertility testing—including clinic visits, labs, medications, procedures, and first-year storage—into one fixed monthly price starting at $249/month. It serves women planning to preserve their fertility, providing clinic matching, a dedicated nurse concierge, and a digital health platform, with pricing focused on the U.S. market.

5 investors

Shen AI provides AI-powered health monitoring technology that uses face-scan analysis to detect vital signs and health metrics from smartphones and connected devices. The platform enables healthcare providers and individuals to conduct real-time health assessments for proactive, predictive care in 40+ countries.

5 investors

Smirk Health creates an AI-powered Benefits Infrastructure Layer platform that provides portable, modular health insurance coverage for the modern workforce including contractors, part-time workers, and gig workers. The platform combines insurance underwritten by Chubb with technology to simplify healthcare benefits administration for employers and increase transparency and flexibility for employees.

5 investors

Soulside builds AI-driven tools for clinicians in behavioral healthcare, including automated clinical documentation and real-time insights. The platform is aimed at behavioral health programs and providers.

5 investors

SoundHealth develops FDA 510(k) cleared, drug-free medical devices that use acoustic resonance therapy via forehead bone conduction to treat nasal congestion and improve sleep. Its products include SONU, a non-steroidal alternative for nasal congestion, and Spatial Sleep, a wearable for sleep, personalized using AI for patients aged 12 and up.

5 investors

Spect provides automated retinal screening to detect conditions like diabetic retinopathy and glaucoma in primary care settings, reducing the need for manual assessment by eye specialists.

5 investors

Spiras Health delivers specialized home-based clinical care through nurse practitioners, nurses, and therapists who assess, diagnose, and treat patients with complex chronic illnesses. The company focuses on improving patient outcomes and reducing healthcare costs by extending specialist care into patients' homes.

5 investors

Sprout is Canada's end-to-end family-building platform that connects users with fertility clinics, expert care, and support resources for fertility treatments, surrogacy, and adoption. The platform serves individuals and couples navigating the path to parenthood through integrated clinical guidance, educational resources, and community support.

5 investors

SPRY PT provides a certified EHR (electronic health record) platform for physical therapy practices, offering clinical modules, FHIR-based APIs, integrations with HIEs, labs, and registries, plus implementation, training, and support services. The Health IT module is certified under the ONC Health IT Certification Program in the United States.

5 investors