Digital Health Startups

CoreMap develops an electrophysiology mapping system to guide atrial fibrillation ablation procedures using electrical activation data. The company serves cardiologists and electrophysiologists treating patients with irregular heart rhythms.

1 investor

Silver builds software to reduce friction in HSA/FSA programs by identifying eligible out-of-pocket medical purchases and automatically adjudicating claims for third-party administrators (TPAs). It serves both consumers seeking to use pre-tax medical savings and the TPAs managing those claims.

1 investor

SilverRide provides ADA-compliant transportation services for older adults and people with disabilities through a network of drivers using their own vehicles. The company operates as a licensed transportation network company across 18 states with a track record of reliable service.

1 investor

Sim&Cure develops software for brain aneurysm and neurovascular treatment, using digital twin and AI technologies to support physicians during endovascular procedures. Its tools are aimed at healthcare professionals and hospitals to improve procedural outcomes and patient care.

1 investor

SimedX operates an AI-powered intensive care platform that uses clinical data to provide decision support for acute respiratory care in critical care settings.

1 investor

SimplePractice provides HIPAA-compliant EHR and practice management software for health and wellness practitioners, with tools for scheduling, billing, documentation, integrated telehealth, insurance handling, and ePrescribe. It is aimed at clinicians treating clients in-person or virtually.

1 investor

SimpleSet is a platform, launched in 2009, that helps clinicians create and share rehabilitation programs with their patients. It serves clinicians and healthcare organizations worldwide focused on physical rehabilitation.

1 investor

SIMPLEX QUANTUM develops AI-powered software libraries that analyze electrocardiogram (ECG) signals to detect cardiac abnormalities, monitor stress levels, and perform biometric authentication for healthcare and wellness applications. The company serves healthcare providers, diagnostic centers, and organizations seeking non-invasive cardiac monitoring and stress assessment solutions.

1 investor

SIMTICS is an online, simulation-based training platform offering 200+ interactive clinical procedure simulations with 3D anatomy models, videos, and quizzes for healthcare learners. It serves healthcare education institutions and their students, and integrates with LMS platforms such as Canvas, Blackboard, Moodle, D2L Brightspace, and Schoology.

1 investor

Baxter provides medical devices, connected care solutions and injectable technologies used across hospitals, physician offices, alternate care sites and home care. Its portfolio spans care communications, infusion and nutrition, diagnostics, pharmaceuticals and surgical technologies for clinicians and patients.

1 investor

Singlera is a biotech company specializing in in vitro diagnostic reagents and instruments. The company focuses on research and development with a team of experts holding advanced degrees.

1 investor

Sinotau develops radiopharmaceutical products, including diagnostic imaging agents for early detection of Alzheimer's disease. The company operates in the radiopharmaceutical sector in China, serving medical institutions and hospitals.

1 investor

Sioslife provides digital care management software and interactive systems designed for elderly care institutions, home support services, and community organizations. The platform enables remote consultations, cognitive stimulation activities, and family connectivity for seniors with varying levels of digital literacy and dependency.

1 investor

Siris Medical develops AI-based decision support for oncology, matching patients against a proprietary database of over 10 million clinical images and 30,000 expert treatments to help oncologists tailor radiation therapy. Its tools serve both healthcare providers and payers, aiming to improve clinical outcomes, automate prior authorization, and reduce care costs.

1 investor

SIRUM works to save lives, with a focus on health equity in underserved communities. The organization builds on experience in public-private partnerships and community health initiatives.

1 investor

SiSU Health operates self-service health check stations that measure cardiometabolic health metrics including blood pressure, BMI, body fat percentage, and diabetes risk for preventive health screening. The company supplies hardware stations to organizations and offers a digital platform to support personalized health improvement.

1 investor

SiteBridge Research is an integrated research organization that connects physicians and patients to clinical trials, with a focus on reaching underserved communities and reducing operational barriers for research sites. The company builds a network of community practices to deliver industry-sponsored clinical research while improving diversity and access in patient participation.

1 investor

SiteLabs works with independent pharmacies in the U.S. to offer preventive health screenings, close gaps in care, and recruit patients for clinical trials, using pharmacies as neighborhood screening and recruitment hubs. It serves independent pharmacies, health plans, and clinical trial sponsors seeking to reach underserved and at-risk populations.

1 investor

Sitero provides institutional review board (IRB) services and an electronic submission system for clinical research studies. The company serves sponsors and contract research organizations managing multi-site research protocols.

1 investor

SiVIEW connects to existing refraction equipment to modernize eye examinations for optical stores, offering AI-assisted exams, remote optometry (teleoptometry), and patient-led autonomous testing. It targets opticians and eyewear retailers to speed up exams, reduce costs, and extend access to vision care.

1 investor

Sketchy is a visual learning and AI-powered case simulation platform that helps medical, nurse practitioner, and physician assistant students master complex concepts using art-driven visuals, micro-stories, and the method of loci for better recall. It partners with medical, NP, PA, and GME programs to prepare learners for clinical decision-making and exams.

1 investor

A charity providing on-site skin cancer screening services to Australian workplaces, combining employee health checks with data collection to inform national skin cancer prevention policy. The organization partners with medical practitioners to deliver full-body skin checks, digital lesion mapping, and follow-up referrals at corporate offices, job sites, and events.

1 investor

Skin Institute is a multi-disciplinary medical provider offering skin cancer surveillance, dermatology services, varicose vein treatments, and cosmetic procedures across 12 clinics nationwide in New Zealand. The company serves patients seeking prevention, correction, and enhancement of skin health through evidence-based medical care.

1 investor

SkinCure Oncology offers GentleCure/Image-Guided SRT, a superficial radiation therapy used as an alternative to Mohs surgery for treating non-melanoma skin cancer. Its technology is deployed at more than 325 dermatology practices across the United States.

1 investor