Digital Health Startups

SpellBound builds mobile augmented reality games and educational tools to engage and distract patients across stages of the care journey, including waiting rooms, clinical point of care, and at-home settings. It serves healthcare providers and their patients.

2 investors

Spencer Health Solutions develops a medication management platform featuring a smart home dispenser that tracks adherence and collects real-world health data for patients and healthcare providers. The system integrates connected devices, mobile and web portals, and pre-loaded pharmacy refills to simplify medication compliance.

2 investors

Spire Health provides continuous respiratory monitoring devices used by pulmonologists and patients to track lung disease. The company's sensors enable remote tracking of chronic respiratory conditions across the United States.

2 investors

Spot Biosystems is a clinical-stage biopharmaceutical company developing non-viral gene therapies using extracellular vesicles as a delivery method. The company targets genetic diseases including muscular dystrophy and cardiac conditions.

2 investors

SpotDoc provides AI-powered full-body skin imaging technology combined with dermatological expertise to detect skin cancer at earlier, more treatable stages. The company uses advanced pattern recognition and imaging analysis to reduce unnecessary biopsies and improve early detection outcomes.

2 investors

Spotlight Pathology develops AI-based diagnostic tools for pathology, particularly focused on blood cancer diagnosis and digital pathology services. The company serves diagnostic laboratories and healthcare centers by providing decision support systems underpinned by machine learning algorithms for image analysis.

2 investors

SpringWorks is a biotechnology company focused on developing innovative treatments for cancer patients. The company combines rigorous scientific research with an operational commitment to rapidly advance therapeutic solutions.

2 investors

sqior provides a digital assistant for hospitals and clinics that understands clinical workflows and delivers relevant information or asks clarifying questions via mobile phone at the moment it is needed. The product is aimed at healthcare staff to support day-to-day operations in clinical settings.

2 investors

Squad Health provides an AI-based service that manages medication access for specialty medical practices, handling prior authorizations, benefits investigation, patient assistance programs, and pharmacy coordination. It serves specialty providers ranging from solo practices to multi-location groups, including those operating buy-and-bill or in-house pharmacies, and is offered free to providers.

2 investors

Squire is an AI tool that analyzes consultation conversations, documents, patient history, and dictations to generate medical reports, forms, and codings in standards like FHIR, SNOMED CT, and ICD-10. It targets healthcare professionals and providers, offering a developer integration and a platform to customize output templates and monitor usage and accuracy.

2 investors

Star Health is an insurance company providing disclosures and financial results to stakeholders under strong governance and ethical practices.

2 investors

Stardots is a company led by startup founders and subject matter experts that develops evidence-based solutions grounded in human and clinical needs.

2 investors

Starling Minds provides digital, self-guided mental health support and training aimed at reducing disability costs and extending care access for organizations and their employees. Its programs offer personalized, profession-based support and outcome data to help employers lower support costs and expand reach.

2 investors

Station is a healthcare company with clinical operations led by medical and nursing leadership, including behavioral health services.

2 investors

Stel provides technology that connects health monitoring devices to electronic health records, transmitting patient vitals without requiring complex setup. It serves health systems and digital health organizations across settings from wellness to hospital-at-home care.

2 investors

A video platform aggregating highlights from 250+ premium content partners and major sports leagues, offering exclusive web distribution rights to curated entertainment, lifestyle, business, news, travel, and finance content.

2 investors

Stresscoach is a mental health and stress management program developed to help users manage emotional challenges and improve wellbeing through applied positive psychology.

2 investors

Stride Soles develops custom orthotics designed using mobile foot scanning technology and clinical data to deliver personalized insoles. The company serves athletes and individuals seeking medical-grade foot support without traditional in-person podiatrist visits and long wait times.

2 investors

StrongMinds is a nonprofit that treats depression using layperson-led interpersonal group therapy (IPT-G), providing free community-based mental health care to people in low-resource settings, with a focus on women and adolescents. It partners with governments and NGOs across African countries including Uganda, Zambia, Kenya, Rwanda, and Tanzania to integrate its model into existing programs.

2 investors

StuffThatWorks operates a patient-powered knowledge base where people with chronic conditions share symptoms, treatments, side effects, and outcomes, which the platform aggregates into real-world evidence. It lets patients join condition-specific communities, compare treatment effectiveness, track their own timelines with AI-surfaced insights, and supports research toward better treatments.

2 investors

Summus Global provides doctor-led clinical navigation and virtual access to specialists across 120+ medical specialties, offering members personalized guidance, second opinions, in-network recommendations, and condition-specific support programs. It operates programs in areas such as oncology, orthopedics and spine, GI health, and heart health.

2 investors

SUN Behavioral operates four psychiatric hospitals and community-based agencies that provide behavioral health and crisis care, aiming to support patients before, during, and after hospitalization. It focuses on continuous, personalized care for individuals with complex behavioral health needs across a range of care settings.

2 investors

Flore creates personalized probiotics based on individual microbiome sequencing, analyzing gut health markers to formulate targeted probiotic blends for each customer. The company serves consumers seeking customized solutions for digestive and gut-brain health issues.

2 investors

Sunny provides an embeddable AI infrastructure for healthcare advocacy, care navigation, concierge, and digital health platforms, handling benefits questions, in-network provider matching, and appointment scheduling under the partner's own brand. It applies eligibility, network, utilization management, and benefit rules to deliver cost-aware member guidance and completes scheduling through existing office channels like phone and fax.

2 investors