Digital Health Startups

Xenoma develops e-skin, a washable garment-type IoT device embedded with stretchable sensors that measures healthcare data when worn. The company uses this technology for at-home medical testing services, including a 3-lead Holter electrocardiogram mailed for home use, aiming at preventive care for cardiovascular and other diseases.

2 investors

YStory develops AI-powered digital health solutions for women, with a focus on menopause management. The company offers JoyHer, a smartphone app that provides symptom tracking, expert articles, and community support for women navigating menopause in Japan.

2 investors

Cardio Intelligence develops AI-based electrocardiogram analysis software as medical device programs, including its SmartRobin AI long-term ECG analysis series and SmartPAFin software for detecting signs of paroxysmal atrial fibrillation. The company is a licensed medical device manufacturer and distributor based in Tokyo, Japan.

2 investors

Digireha (株式会社デジリハ) develops digital rehabilitation tools for people with disabilities, working under the mission of building a future not constrained by disability. The company frames disability through the "social model," treating the difficulties disabled people face as originating in society rather than the individual.

2 investors

Japanese healthcare startup (Mental Health Technologies, Inc.) that runs businesses in mental health solutions, medical workforce shift services, medical career support, and digital marketing, centered on connecting companies with physicians to address employees' physical and mental health. It serves corporate employers seeking to improve workforce well-being and occupational health.

2 investors

Rehasaku offers rehabilitation software that combines physical rehabilitation with IT, aiming to make rehab part of everyday life. It runs two service lines: one for medical institutions and one for treatment clinics/therapy practices in Japan.

2 investors

Synyi builds AI and large language model tools for hospitals and clinics, including AI-assisted diagnosis and consultation, clinical decision support and quality control, hospital operations management (using DRG/DIP and performance metrics), and clinical research platforms. Its products serve healthcare institutions to standardize clinical workflows, improve care quality, and support multi-center research.

2 investors

C&R Research is a contract research organization providing end-to-end clinical trial services, including regulatory and non-regulatory trials as well as multinational studies. It has conducted around 1,800 clinical trials, including 79 global multinational trials, over 29 years.

1 investor

A telehealth service for men's hair loss that uses an online assessment and doctor consultations to prescribe personalised, compounding-lab-formulated topical and oral treatments for male pattern balding. Treatments are shipped to the patient with ongoing follow-up consultations and subscription-based delivery.

1 investor

119 is a patent-pending mobile and wearable system that acts as a modern medical ID, communicating a user's medical information to bystanders or first responders via QR code and guiding them through the appropriate emergency response. It serves people with chronic health conditions, offering pre-set emergency messaging and a bystander questionnaire to avoid unnecessary 911 calls.

1 investor

19Labs builds GALE, a smart point-of-care platform that brings a full clinic experience to schools, rural communities, and pharmacies. The company focuses on providing telemedicine and healthcare access to underserved rural populations worldwide.

1 investor

One Mnet Health provides technology and services that turn healthcare data into insights for healthcare providers, supporting workflow automation, patient engagement, personalized care, and revenue and payment management. It serves providers across the United States, helping manage patient balances and improve operational efficiency.

1 investor

20/20 BioLabs develops laboratory blood tests using machine learning for the early detection of cancers and chronic diseases, including a multi-cancer early detection (MCED) protein tumor marker test and an inflammation biomarker test. Its tests use at-home upper-arm capillary blood collection and target individuals and healthcare providers.

1 investor

3Sunny develops CAREBOOK, a cloud service that lets hospitals and medical/care institutions handle patient admission and discharge coordination online, replacing phone and fax workflows with features like bulk inquiries to multiple facilities, per-case chat, and document attachment. The company serves the medical and elderly-care sector in Japan.

1 investor

32 Biosciences develops gut mucosal-immune science to prevent and treat gastrointestinal diseases, offering a GI discovery platform that measures metabolomic signatures of the gut mucosal-immune system and a therapeutic platform based on a Mucosal Immune Modulator (MIM) that restores and protects the gastrointestinal mucosal-immune barrier. Its lead therapeutic asset is CS-0003.

1 investor

360 Health Technologies builds human-centered digital health and wellness platforms, combining psychology, technology, medication, and coaching. Its products include MIRA Health, an insulin-resistance and lifestyle app, and MyNutriPro, a content and client management platform for health practitioners, along with custom app development and API integration services.

1 investor

360Moms is a mobile app offering parenting and family care support, combining AI with a network of over 400 doctors and specialists to answer parents' questions and provide guidance. It also provides parenting tips content, healthy recipes, and family discounts, serving a community of over 100,000 families in Arabic-speaking markets.

1 investor

3D-Side provides an AI-powered web platform for 3D preoperative planning and the creation of patient-specific medical devices, connecting doctors, patients, and medical device companies. It serves healthcare professionals and medical device firms with tools covering the full patient journey from planning through post-market surveillance, including arthroplasty and bone-resection solutions.

1 investor

3X4 Genetics offers a genetic testing service using a cheek swab that maps an individual's genes across 35 pathways and 10 health categories, delivering personalized health and wellness recommendations through an app and PDF report. It uses proprietary AI and genetic research to guide consumers toward health and weight goals, and results can be shared with practitioners.

1 investor

3Y Health provides a practice management platform for healthcare clinics that handles backend operations including scheduling, billing, credentialing, insurance verification, payroll, and reporting. It offers faster payouts to clinicians and AI tools for automated documentation and charting, serving practices of any specialty or size that work with insurance plans.

1 investor

4bases develops clinically-validated diagnostic genetic tests, including companion diagnostics and tests for inherited gene mutations, used by healthcare professionals to support therapeutic decisions in precision and preventive medicine. The company operates as an ISO13485-certified, CE-IVD compliant in vitro diagnostics provider.

1 investor

4DMedical develops analytical software that extracts detailed lung function data from standard X-ray and CT scans, enabling non-invasive diagnosis and tailored treatment of respiratory conditions. Its technology serves clinicians and healthcare providers, including VA hospitals treating veterans exposed to toxic substances and airborne hazards.

1 investor

4G Clinical builds randomization and trial supply management (RTSM) technology for complex clinical trials, serving biotech, biopharma, and CRO sponsors. Its software handles randomization, drug supply forecasting, scenario modeling, and system integrations across the study lifecycle.

1 investor

6 Degrees Health provides healthcare cost containment solutions built around reference-based pricing, helping employers offer affordable health plans while working with providers on payment accuracy and integrity. It focuses on driving transparency and controlling healthcare costs.

1 investor