Deep Tech Startups

Lumitron Technologies develops laser-Compton light sources that produce monochromatic x-ray and gamma-ray outputs for ultrahigh-fidelity imaging, ultra-low dose radiography, and precision radiotherapy. Its technology targets medical applications such as FLASH radiotherapy and k-edge subtraction imaging, as well as element- and isotope-specific material identification.

3 investors

Lumius develops a 3D ultrasound device designed to provide fast, smart, and accessible imaging capabilities. The device functions as a 3D camera for internal body visualization, serving the medical imaging market.

3 investors

Lummus Technology is a global technology provider offering expertise across science, engineering, and technology to serve industrial customers. The company operates through specialized capabilities and affiliate companies to deliver solutions across multiple domains.

3 investors

Lumotive develops optical beamforming semiconductors for programmable optics applications. The LCM Development & Evaluation Kit is a commercial platform enabling rapid prototyping and 3D sensing system development across various industries.

3 investors

Lunaphore develops spatial biology solutions that enable scientists and clinicians to analyze tissue structure and cellular composition. The company was acquired by Bio-Techne in 2023 to expand the combined entity's capabilities in applied spatial biology.

3 investors

Luyef develops precision fermentation and cell-based technologies to produce animal-derived products for food, biomedicine, and cosmetics without factory farming or environmental impact. The company targets industries seeking sustainable, ethical, and cost-effective alternatives to conventional animal-based materials.

3 investors

Lydian develops and supplies technology for producing sustainable aviation fuel (SAF) from CO₂, enabling aircraft fuel producers and facilities operators to manufacture drop-in jet fuel at lower capital and operating costs than conventional methods.

3 investors

Lyell develops CAR T-cell therapies for cancer patients by leveraging deep expertise in T-cell biology and oncology. The company operates an integrated pipeline spanning discovery through manufacturing and clinical trials, with its own manufacturing facility in Washington.

3 investors

Lynk Pharma develops pharmaceutical products for rheumatoid arthritis and ankylosing spondylitis, with selective licensing arrangements for regional commercialization.

3 investors

MACSO develops technology that makes AI, IoT, and edge computing capabilities more accessible and cost-effective for industries. The company positions itself around data-driven innovation across sectors.

3 investors

MAKO develops Flightfilm, a biomimetic coating inspired by shark skin that reduces aerodynamic drag on aircraft to improve fuel efficiency and support Net Zero carbon goals in aviation.

3 investors

Mana develops proprietary sodium-ion battery cell designs and electrolytes for applications including defense, aerospace, industrial power backup, datacenters, and electric vehicles. The company partners with established manufacturers to scale production of its anode-free sodium-ion battery technology.

3 investors

Ayrton Energy develops liquid organic hydrogen carriers using electrolysis to enable safe storage and transport of hydrogen through existing fuel infrastructure, reducing costs by up to 50 percent. The company serves the hydrogen and energy sector by addressing the bottleneck in hydrogen storage and distribution.

3 investors

Matter builds superintelligent vision systems for the physical world, leveraging experience from space and Mars instrumentation. The company serves applications requiring advanced visual intelligence and perception capabilities.

3 investors

MechanoCross is a Hokkaido University spin-out that develops and provides mechanochemical organic synthesis technology, including solvent-free "mechano" reaction methods and insoluble high-performance materials. It aims to enable chemical manufacturing that reduces reliance on petroleum resources and carbon emissions for industrial and pharmaceutical producers.

3 investors

Medic Life Sciences applies CRISPR functional genomics in 3D patient tumor-like cancer models to identify biomarkers, synthetic lethality, and resistance mutations for oncology drug development. The company focuses on discovering genetic features of cancer with translational relevance for stratifying patients and finding novel drug targets.

3 investors

Medium Bio engineers customized proteins using AI and protein design to create affinity reagents for research teams and diagnostic developers. The company accelerates molecular tool development from design to experimental validation within weeks.

3 investors

Meiogenix develops a proprietary recombination technology that targets meiotic recombination to accelerate genetic gain and variety development in crops. It serves plant breeders through crop innovation partnerships and large-scale technology licensing, working on both specialty crops (tomato, fruits, vegetables) and field crops (corn, rice, wheat, soybean).

3 investors

MEL Science builds science education products and experiences, primarily using VR/AR technology, for students and lifelong learners. The company's mission is to make science engaging and accessible through digital and immersive learning tools.

3 investors

MemryX develops edge AI accelerator hardware and software solutions designed for efficient deployment across embedded systems. The company serves manufacturers and enterprises seeking to deploy AI at the edge with minimal data movement and software complexity.

3 investors

Metagenomi is a genetic medicines company developing therapies based on gene editing technologies to treat patients with serious diseases. It operates in the biotech sector, working on translational and clinical development of genetic medicine programs.

3 investors

MetaGravity is a deep tech company building the Quark Network Engine, a distributed compute platform based on a causal partitioning model that scales computation across cloud and edge. Its technology powers real-time simulation use cases including multiplayer games, defense simulation, digital twins of urban environments, and decentralized computing, alongside the Spinor platform for distributed AI inference and scientific computing.

3 investors

MEXT builds software that uses AI below the application layer to make high-capacity system flash storage appear to the operating system as DRAM-speed memory, expanding usable memory capacity by 2-4X. The technology is aimed at addressing DRAM supply constraints for data centers and AI workloads. The company was acquired by AMD.

3 investors

MiCAN Technologies produces immortalized blood cells (erythroid and myeloid-lineage cells) using regenerative medicine technology, supplying research-use blood-like cells, evaluation kits, and contract testing services. Its products serve infectious disease research and the efficacy/safety evaluation of pharmaceuticals and functional materials, including a pyrogen (fever-inducing substance) alternative testing kit.

3 investors