Deep Tech Startups

xLight develops free-electron laser (FEL) technology and advanced accelerator systems. The company builds x-ray science facilities and instrumentation for ultrafast science and research applications.

5 investors

Xylo develops mechanism-based drug therapies targeting psychiatric and neurological disorders using computational and rational drug design approaches. The company serves patients and healthcare systems seeking novel treatments for complex neuropsychiatric conditions.

5 investors

ZuriQ develops quantum computing hardware based on a three-dimensional trapped-ion architecture designed for scalable qubit systems while preserving connectivity and operation fidelity. The company targets industrial quantum computing applications such as drug discovery.

5 investors

Alivexis is a drug discovery company that develops small molecule therapeutics targeting cancer, immune-inflammatory conditions, and rare diseases, leveraging computational platforms and disease biology expertise across operations in Japan and the US.

5 investors

ThinkCyte develops diagnostic devices and cellular analysis platforms using imaging flow cytometry and microfluidics technology. The company serves research institutions, clinical laboratories, and biopharmaceutical companies in the life sciences and diagnostic tools sector.

5 investors

Orbital Lasers develops space optical technology centered on satellite lasers, including systems aimed at addressing space debris, satellite bus, and mission instrument development. The Japanese company works in the space and deeptech sector serving the emerging NewSpace market.

5 investors

Emulsion Flow Technologies (EFT) develops solvent-extraction technology known as "emulsion flow," rooted in nuclear science research, to address resource and environmental problems including lithium-ion battery recycling and PFAS recovery. The company applies element-separation and extraction processes toward sustainable materials recovery.

5 investors

Modalis Therapeutics develops therapeutics using CRISPR gene-editing technology and provides its platform technology for drug development. It operates in the biotechnology sector.

5 investors

3DEO is a metal 3D printing company that produces high-volume small metal parts and components using its patented Intelligent Layering process, paired with a Design for Additive Manufacturing service. It serves companies in the medical, aerospace, industrial, consumer products, automotive, and semiconductor industries.

4 investors

ABL Space Systems builds small satellite launch vehicles and a containerized launch system designed to enable orbital launches from flat pads in different locations. Its offerings target customers needing transportable, lower-cost access to space.

4 investors

Actasys develops ActaJet air-jet cooling technology that provides spot-on thermal management for high-density data center server racks and components such as Network Interface Cards, Data Processing Units, and Switches. The ultra-compact, energy-efficient system targets data centers running AI and high-rate data processing workloads.

4 investors

Actual is a company applying software and a multidisciplinary approach to problems spanning energy, transportation, and aerospace, drawing on experience across industry, academia, and software. The page does not detail a specific product offering.

4 investors

Aemon builds autonomous AI research systems that solve hard technical optimization problems by self-accelerating experimentation within customer codebases. The system learns from the frontier of research, runs experiments, and delivers validated technical breakthroughs for enterprise customers.

4 investors

After Thought is a private interdisciplinary research lab working on new approaches in artificial intelligence and computational cognitive science.

4 investors

AfterQuery is an applied research lab that curates training data solutions for foundation model development by capturing expert reasoning and decision-making processes. The company works with domain experts to transform real-world professional work into structured datasets that teach AI models how to solve complex problems through step-by-step reasoning rather than just outputs.

4 investors

Agile Analog develops and automatically generates customizable analog IP for semiconductors using its Composa™ technology, serving ASIC and SoC designers across applications in high-performance computing, IoT, AI, automotive, and aerospace.

4 investors

Agscent develops emissions monitoring and breath analysis systems for detecting greenhouse gases and biological markers. The company offers commercial-grade platforms for environmental monitoring and non-invasive diagnostic analysis across agricultural, animal health, and human health applications.

4 investors

Ahammune develops therapeutic treatments for chronic skin diseases with unmet medical need. The company aims to address dermatological disorders through scientific innovation and comprehensive treatment strategies.

4 investors

AID:Tech delivers international aid and payments using blockchain technology, with a focus on digital identity. The company enables individuals to own and control their self-sovereign identities.

4 investors

Aikium combines deep learning with large-scale wet-lab experimentation to design and screen protein libraries, aiming to develop protein therapeutics for hard-to-treat targets such as GPCRs and ion channels. The company focuses on drug discovery for parts of the human proteome that conventional antibodies and small molecules cannot address.

4 investors

AIMATX operates an AI platform for materials discovery that predicts material properties and guides targeted experimentation to shorten research cycles. It aims to reduce the time and cost of developing new materials from years to weeks or months.

4 investors

Akin builds frontier AI models and AI-powered software and hardware, with a stated focus on "Public Benefit AI" and human wellbeing. It applies its technology to areas such as space missions, wellbeing clinical trials, and generative AI, working with universities, clinical partners, and an expert advisory board.

4 investors

Alamar Biosciences develops NULISA, an ultra-high-sensitivity, high-specificity technology for analyzing hundreds of protein biomarkers from small biofluid samples, building on the team's prior spatial genomics work (RNAscope). The company serves proteomics research and clinical drug development applications.

4 investors

Albotherm develops a heat-activated coating for adaptive glazing that changes transparency in response to temperature, validated in commercial greenhouse trials and in development for the built environment, energy, and mobility surfaces. It targets horticulture growers, commercial building glazing, and PV/vehicle applications as a passive alternative to chalk shade paint and electrochromic or motorised systems.

4 investors