Deep Tech Startups

VerAvanti develops ultra-small, single-use endoscopic imaging devices using patented scanning fiber technology for minimally invasive procedures. The company focuses on enabling clearer visualization and more efficient workflows for physicians during diagnostic and therapeutic interventions.

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Veridify develops quantum-resistant security solutions for constrained IoT and operational technology devices across industrial, building automation, critical infrastructure, and automotive sectors. The company provides embedded security toolkits and the DOME platform for secure device onboarding, authentication, and ownership management across globally distributed low-resource edge devices.

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Verismo is a biopharmaceutical company founded by the inventors of Kymriah, the first FDA-approved CAR T cell therapy, developing next-generation CAR T therapies using KIR receptor technology to address limitations in first-generation approaches.

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Verseon uses quantum physics-based modeling combined with AI to design novel small-molecule drug candidates for major human diseases. Its pipeline targets conditions including cardiovascular disease (anticoagulants), diabetic vision loss, multidrug-resistant cancers, and solid-tumor metastasis, with candidates ranging from preclinical to clinical stages.

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VERSES builds Genius, an AI system based on active inference and "digital brain" architecture that models cause-effect relationships and quantifies uncertainty to produce explainable, domain-specific predictions. It targets enterprise and financial services clients, including Fortune 500 companies and asset managers, offering cognitive AI as an alternative to generic machine learning tools.

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Vesicor develops precision-engineered cellular microvesicles that deliver p53 mRNA to cancer cells using a non-viral, immune-silent platform, aiming to restore tumor suppression in advanced solid tumors. Its lead candidate, ecm-RV/p53, and broader platform are designed for oncology therapeutics and multiple payload types.

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VesselOn is a drug development company using a platform to create enhanced versions of monoclonal antibodies, small molecules, cytokines, proteins, and other therapeutic conjugates, with initial focus on improving anti-PD-1 cancer drugs such as Keytruda. It works in the biopharmaceutical and oncology space to produce proprietary drug candidates.

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Vibrant Composites develops precision tap-based haptic actuators for wearable devices, moving beyond conventional vibration motors to enable distinct tactile signals. Its technology supports tactile communication systems and non-visual "tactile language" through continuously worn hardware.

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Vibrant provides nondestructive testing (NDT) inspection technology using patented PCRT (Programmable Chromatic Resonance Technology) for manufacturing quality control. The system uses vibrational pattern recognition to detect flaws and material defects in parts across industries including aerospace, turbine, and automotive manufacturing.

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Villya Pharmaceuticals develops water-soluble reformulations of existing drugs using a patented carbohydrate-loading technology, including liquid praziquantel, a topical gel for Female Genital Schistosomiasis, second-generation erectile dysfunction medications, and oral peptide therapeutics such as semaglutide and insulin. The company focuses on improving solubility, gastric stability, and delivery of pharmaceuticals to enable oral administration of otherwise injectable medicines.

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Visionary Fiber Technologies (VFT) develops reactor and processing technology applied in chemical processing, including applications relevant to oils and fats as presented at the AOCS Annual Meeting & Expo.

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Vitanova Biomedical develops cancer treatments based on a proprietary light-activated intracellular acidosis (LAIA) therapy that uses upconverting nanoparticles and deep-penetrating light to induce cancer cell death. The company operates in the biomedical and oncology therapeutics space.

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Volcano Platforms is an early-stage startup building physics-based computational fluid dynamics (CFD) simulation software that automates first-principles engineering simulations and generates synthetic data for AI. Its VOLCANO ScaLES product targets engineering and simulation workflows.

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Vuzix develops waveguide optics, display systems, and OEM platforms for device makers, and designs and manufactures enterprise AI smart glasses for warehouse, field service, healthcare, and industrial use. Its products and OEM programs serve defense, enterprise, consumer, and medical markets.

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Weinberg Medical Physics develops compact clinical MRI systems using pulsed power, electropermanent magnets, and additive manufacturing to produce rapid high-resolution imaging for use in dentistry, oncology, and urology practices. It also engineers custom-shaped magnetic nanoparticles that can be propelled through the body to deliver drugs for treating disease.

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Whooshh develops technology solutions for fish handling, monitoring, and passage in aquatic environments. The company serves water utilities, fish hatcheries, and environmental agencies managing fish populations and migration.

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Widetronix develops ultra-low power sensors enabled by betavoltaic power sources based on wide bandgap semiconductor materials, serving applications requiring autonomous, maintenance-free power. The company commercializes silicon carbide betavoltaic technology spun out from Cornell University.

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XDemics develops cell culture and biomanufacturing technologies for generating mammalian cells at high densities for advanced therapy production. The company's HDCR platform and related products enable researchers and GMP facilities to produce T cell, stem cell, and viral-based therapies with improved quality and consistency.

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YAN Engines is developing technology to improve the efficiency of the internal combustion engine, drawing on the team's automotive and power-generation R&D background. The company works in engine and powertrain engineering for the energy and automotive sectors.

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Yatiri Bio applies unbiased proteomics, deep learning, and patient-derived cellular models to cancer drug discovery, building a molecularly defined patient landscape to identify ideal patient subsets for novel therapeutics. It offers computational tools such as its ProteoBrowser data portal and ProteoModels cellular systems for oncology drug developers working on personalized medicine.

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Yost Labs develops sensor fusion firmware and 3-Space inertial sensors (combining gyroscope, accelerometer, and magnetometer) that determine real-time orientation for motion tracking. Its products, ranging from surface-mount PCBs to wireless full-body motion capture systems, serve applications in virtual reality, drones, autonomous vehicles, robotics, medical rehab, and athletics.

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Zapata Quantum is a publicly traded company (OTCQB: ZPTA) that applies agentic AI to accelerate quantum algorithm development by automating quantum resource estimation workflows. Its efforts target quantum chemistry applications such as drug discovery, energy, and advanced materials development.

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Zasti builds AI/ML applications for ClimateTech, AgTech, and healthcare, drawing on geospatial systems and climate models. The company applies data science and machine learning across climate, agriculture, and digital health domains.

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Zoic Capital is a venture capital firm that invests from Seed to Series A in early-stage health and hard-science startups with strong intellectual property. It focuses on frontier technologies addressing defined problems, working closely with founders on IP strategy and commercialization.

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