Deep Tech Startups

ASP (ASP Isotopes) is an advanced materials company developing proprietary technology and processes to produce and enrich isotopes for markets including nuclear medicine and therapeutics, green energy generation, and quantum computing. Its initial focus is constructing plants in South Africa to produce highly enriched isotopes for the nuclear medicine market.

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Astound Research monitors federal and non-federal research funding sources and helps academic and lab researchers find, apply for, and secure grants by identifying relevant opportunities, creating required content, and connecting collaborators. It serves scientists and research labs seeking external funding.

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Astrotech develops mass spectrometry and molecular analysis instruments derived from space-grade engineering, used for detecting trace explosives, confirming synthetic opioids at borders, and monitoring VOCs in the field. Its products target security, border control, and field-testing applications requiring rugged, reliable detection tools.

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Atsign provides technology for privacy and security, device administration, and connectivity, working with system integrators, IT solutions providers, security consultants, platform providers, and device makers. Its offering targets deployment of secure, private connected systems and IoT devices.

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Augmntr is a systems engineering and software development firm that builds real-time intelligence systems combining edge AI, multi-modal sensing, and spatial computing for use in low-bandwidth, time-critical environments. It serves defense and commercial sectors, connecting sensors to field-ready platforms that support real-time decision-making.

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Autonomix is developing a catheter-based platform that senses nerve activity in real time and performs targeted transvascular denervation, allowing physicians to map, ablate, and verify nerve signaling during a procedure. Its initial focus is interventional chronic pain management for pancreatic and other visceral cancer patients, with planned expansion across cardiology, pain management, pulmonology, and gastroenterology.

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Autonomous Marine Systems (AMS) builds the DATAMARAN, an autonomous multi-hulled sailing platform for long-dwell ocean sensing and data collection. The company serves customers in offshore energy, offshore wind, coastal monitoring and defense sectors, and was acquired by JASCO Applied Sciences in July 2024.

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Aveta Biomics develops cancer therapeutics based on Orthologous Molecular Structures (OMS), metabolites from organisms with orthologous genes and processes, combined using an evolutionary-biology-based platform. Its drugs aim to treat and prevent cancers while addressing tumor heterogeneity and drug resistance.

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Axon builds technology for public safety, including conducted energy weapons and training programs used by police agencies to reduce gun-related deaths and improve emergency response. Its products support law enforcement decision-making and safer outcomes.

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AxonVR develops haptic technology for virtual reality, including HaptX Skin (a microfluidic haptic textile that simulates touch, texture, and temperature), HaptX Skeleton (a force-feedback exoskeleton), and a HaptX SDK for developers. It works with enterprise clients to build immersive VR experiences with realistic touch feedback.

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Axtra3D develops advanced additive manufacturing (3D printing) solutions using proprietary optoelectronics-based technologies for industrial and commercial applications. The company manufactures the X1 Series of printers powered by its patented Hybrid PhotoSynthesis technology.

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Azak develops modular, self-propelled wheel technology that converts standard containers and platforms into motorized vehicles. The company serves customers seeking alternative mobility solutions for cargo and material handling.

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Badwater Alchemy develops produced water treatment solutions using nano materials to remove contaminants from oil and gas operations at significantly lower cost than thermal desalination. The modular systems recover over 80% of water while reducing brine disposal volumes and potential seismic risks.

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Baker Street Scientific operates a data intelligence platform that uncovers hidden associations and patterns within large datasets to support decision-making across organizations and industries. The company uses an associative and predictive engine to transform raw data into actionable intelligence for both common and complex business decisions.

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Balboa Geolocation develops geolocation technology and AI/ML systems, serving first responders, government agencies, and enterprise customers. The company leverages expertise from aerospace, defense, and sensor technology sectors.

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Beamlink builds adaptable cell tower infrastructure, including the Bentocell, a software-defined radio unit that covers cellular bands from 600 MHz to 4 GHz using a single hardware design. The company targets telecom carriers seeking to expand mobile coverage and to deploy or rebuild cell sites in disaster zones and underserved areas.

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Bectas Therapeutics is a biotech company operating in the therapeutic development space. The page features CEO Ronan O'Hagan discussing biotech industry insights, leadership, team building, and organizational culture.

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Bell Copper is a publicly traded mineral exploration company (TSXV: BCU; OTCQB: BCUFF) focused on discovering large-scale porphyry copper systems in Arizona. Its assets are the wholly owned Big Sandy Project and the Perseverance Project, a joint venture with Cordoba Minerals, both located in northwestern Arizona near Kingman.

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BioConsortia discovers and develops microbial biological products for agriculture, using microbial engineering and field validation to create seed-applied and soil-directed solutions that enhance crop productivity and sustainability. The company serves global agriculture stakeholders seeking biological alternatives to synthetic inputs.

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Bitbison builds a system of record that captures a complete, causal history of activity across systems — from developer workstation through build to production — to enable runtime security detection, policy enforcement and audit. It works at the kernel, networking and storage layer to capture events with low overhead for infrastructure security teams.

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Bluespec develops tools and IP for hardware and embedded systems developers, with a focus on RISC-V technology for core evaluation, software development, acceleration, and verification. The company also maintains an open source family of RISC-V cores.

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bluShift Aerospace develops MAREVL modular hybrid rocket engines powered by a proprietary non-toxic biofuel, used for boosters and small launch vehicles as well as dedicated suborbital flights. The company serves researchers and technology-demonstration customers, offering microgravity research time and STEM education programs through its launches.

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BNNT Materials produces boron nitride nanotubes (also called white graphene nanotubes), strong and flexible nanoscale ceramic fibers for industrial applications. The technology and team were spun out of NASA and US Department of Energy national labs.

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Botlink develops drone software, including the Botlink app, used across industries such as agriculture, mining, roofing, and public safety. The company focuses on autonomous systems and drone technology.

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