Deep Tech Startups

Typewriter Therapeutics develops mRNA-based gene therapies using a platform for targeted insertion of therapeutic genes, building on transposon research from the University of Tokyo. It aims to treat patients with severe genetic disorders, with research facilities in Tokyo and Cambridge, USA.

1 investor

Tyris Therapeutics develops non-viral gene therapies using a proprietary DNA format (oDNA™) to treat rare and prevalent genetic diseases. The company aims to provide safer, controllable treatments that can accommodate genes of any size, with the ability to adjust dosing and allow for retreatment.

1 investor

U2U Network provides a Layer-1 blockchain built on a DAG and Helios consensus for DePIN (Decentralized Physical Infrastructure Network) applications, offering EVM compatibility, high throughput, and a hub to access decentralized apps and shared resources. It serves DePIN projects and developers seeking to scale peer-to-peer resource-sharing services such as decentralized VPNs and DeFi.

1 investor

UbiquiTx develops an AI-native platform for programmable modulation of the proteome, using modular constructs that pair AI-designed guide peptides with swappable effector enzymes to degrade, stabilize, or relocalize target proteins. The company runs a validation business and a therapeutic pipeline in oncology and regenerative disease.

1 investor

UCAP Power designs energy components and instant power solutions for critical infrastructure applications including automotive, data centers, electrical grids, and wind energy systems. The company focuses on delivering stable, reliable power distribution technologies for industrial and utility sectors.

1 investor

A robotics company developing general-purpose industrial humanoid robots designed to perform hazardous and physically-demanding tasks in manufacturing and industrial settings. The company has shipped its first industrial humanoid robot in the U.S. and continues to develop successive generations of robotic platforms.

1 investor

UFA develops integrated software and training solutions for safety operations across aviation, including air traffic control systems, pilot training, and airside operations for both civil and military sectors.

1 investor

UltiMaker manufactures 3D printers and related materials for product design and development across industries including consumer electronics, industrial products, and medical devices. The company offers two printer series (S and Method) and over 300 materials ranging from polymers to composites to metals.

1 investor

Vizgen develops high-throughput spatial profiling technologies, including MERFISH-based spatial genomics and spatial proteomics tools for life science research and precision oncology. The company (which merged with Ultivue) serves biopharma and research customers with instruments and reagents for spatial biology.

1 investor

Ultralight is a GPU-accelerated HTML rendering toolkit for embedding modern HTML into games and native applications, available for C and C++ across platforms including Windows, macOS, Linux, Xbox, and PlayStation. It is built on a lightweight fork of WebKit and developed in collaboration with game studios.

1 investor

UM6P Ventures is a venture capital firm that provides seed and early-stage investment to science and technology startups across Morocco and Africa. It supports entrepreneurs through capital, access to research labs, academic partnerships, and mentorship networks.

1 investor

Unblur develops IRIS Core, software that provides real-time situational awareness and coordination tools for incident commanders managing emergency response operations. The platform optimizes decision-making and team coordination across emergency services and other industries requiring operational response management.

1 investor

Uncharted AI builds a full-stack mineral exploration platform that combines legged robots, fused sensing (LiDAR, hyperspectral, magnetometry, and custom geophysical sensors), and AI models to produce interactive 3D subsurface models without drilling. It targets critical mineral exploration in difficult terrains, aiming to lower cost and improve success rates for the mining and exploration industry.

1 investor

Undesert Corporation develops a patented desalination technology called the SWAP system that produces fresh water using less than half the energy of conventional methods, without membranes, chemicals, or brine waste. It targets water-stressed coastal communities, water-intensive industries, and arid agricultural regions.

1 investor

Unio develops patented water treatment technology that uses centrifugal force to remove pollutants and suspended solids from water without barrier membranes. It serves municipal water treatment, laundry waste water, and industrial applications such as geothermal brine, carbon fibre recycling, pharmaceutical, and plastics recycling processes.

1 investor

Union Peak is a venture capital firm that provides funding and network support to deeptech founders, helping source and collaborate on early-stage ideas.

1 investor

Uniseed is a commercialisation fund that provides seed capital, mentoring and network access to researchers from its partner research organisations, helping them turn technology innovations into products and businesses. It invests across a broad range of technology sectors and has exited twelve investments to date.

1 investor

UniServices is the University of Auckland's research commercialisation and growth team, working to develop and commercialise the university's research expertise across research, innovation, and industry. It operates within the University of Auckland in New Zealand.

1 investor

UniverCell is an electrode and cell producer developing battery manufacturing technologies and operates a gigafactory in Europe with capacity to scale beyond 1.5 GWh. The company serves renewable energy and battery markets by optimizing production processes and replacing hazardous substances with environmentally friendly alternatives.

1 investor

Universal Fuel Technologies (UniFuel) is a chemical technology company whose Flexiforming process, patented across 12 countries, lets fuel and energy producers convert existing refining facilities to produce renewable fuels. It serves refiners and the aviation/energy sector transitioning from fossil to renewable fuels.

1 investor

UniSCool is a thermal management technology company spun off from the University of Lleida and Université de Sherbrooke, developed through over €500k in publicly financed research projects. The company serves industrial and commercial sectors requiring advanced thermal solutions.

1 investor

Flintbox (Wellspring Scout) operates an innovation search platform that aggregates patent records, scientific publications, research grants, startup data, and licensable technologies into a searchable database. It serves researchers and organizations seeking to discover patents, publications, grants, and licensable technology across global patent offices.

1 investor

Unixell Biotech develops advanced cell therapy platforms including reprogramming, stem cell differentiation, lineage tracing, and gene editing technologies to create neural cell therapeutics for clinical applications. The company's lead program is UX-DA001, a midbrain dopamine precursor cell therapy for Parkinson's disease, which has received clinical trial approval from Chinese and US regulatory authorities.

1 investor

Unjo develops customized motor controllers and integrated motor control systems for demanding industrial applications. The company combines hardware, software, and control engineering expertise to optimize motor performance, energy efficiency, and system effectiveness for both external customers and projects within its parent company HYDAC.

1 investor