Deep Tech Startups

Signet Therapeutics develops targeted cancer drugs using cancer organoid models combined with artificial intelligence. The company focuses on discovering novel therapies for cancers that currently lack effective treatment options.

1 investor

Silent Capital is a private venture syndicate that gives its accredited-investor members access to multi-stage aerospace, defense, and deep tech deals. It partners exclusively with the early-stage defense and deep tech fund Silent Ventures.

1 investor

Silentium develops embedded software and controller hardware that use adaptive algorithms to cancel noise and shape sound in real time, replacing heavy passive acoustic materials. Its Active Acoustic Management platform targets automotive and transportation applications, enabling features such as active noise cancellation and zone-based personalized audio.

1 investor

Silentium Defence designs and deploys passive radar systems and related software for covert, low-emission surveillance across air, land, maritime and space domains. It serves defence, government and commercial customers with situational awareness, mission planning tools and space surveillance data feeds.

1 investor

Si-Lib develops pure silicon anodes for lithium-ion batteries, a materials technology aimed at energy-storage applications. The company originated from research at Tel Aviv University.

1 investor

Silicon Quantum Computing develops fault-tolerant quantum processors using atomic-scale manufacturing techniques, targeting applications in AI acceleration, quantum simulation, and quantum computing. The company builds a full-stack solution from processor fabrication through control systems and software.

1 investor

Silixa develops distributed fibre optic sensing systems for real-time monitoring in energy, infrastructure, and environmental applications. The company's technologies enable high-density sensor coverage across extended areas for subsea seismic acquisition, microseismic monitoring, and structural sensing to support energy production and carbon storage verification.

1 investor

Siloton develops photonic chip technology that miniaturizes the optical hardware behind OCT (optical coherence tomography) eye scanning onto a coin-sized chip, enabling a portable eye scanner for use in clinics, community settings, and at home. It also offers OCT-Chip Development Kits for other market segments, targeting ophthalmic diagnostics and medical imaging.

1 investor

Silver develops a miniaturized Raman spectroscope paired with proprietary nanoparticle substrates that lets consumers instantly detect contaminants and toxins. It targets the consumer market with a low-cost handheld toxin-detection device.

1 investor

Silvertech is commercialising a patented lateral silicon carbide (SiC) FET transistor technology aimed at improving power MOSFETs used for power conversion in applications like EVs, data centres, grid synchronisation, and inverters. Developed with Griffith University's Microtechnology Centre, the company targets renewable energy and power electronics with devices intended to be cheaper, smaller, and more efficient than existing SiC and GaN options.

1 investor

SILVEX applies a conductive coating to textiles that provides electromagnetic field shielding while maintaining the fabric's original feel and appearance. The dip-and-dry process integrates into existing textile manufacturing workflows for consumer apparel, automotive, aerospace, military, and healthcare applications.

1 investor

Simnovus develops simulation and emulation tools for validating 5G radio access networks, serving telecommunications and network operators through software-based testing platforms.

1 investor

SimpleDirect is an independent AI lab that develops open-weight language models (8B, 30B, and 123B) released under the Vinci brand, along with developer tools and research on AI model behaviour and evaluation reliability. It serves developers and organizations looking to run models locally and study AI evaluation methods.

1 investor

Simplex Micro designs RISC-V microprocessor intellectual property, including scalable vector processors that range from 1 to 8-wide architectures. The company serves semiconductor and system-on-chip developers requiring high-performance CPU designs.

1 investor

Simpulse develops embedded Software-Defined Radio (SDR) modems and radio link solutions for long-range, secure communication in mobile and harsh environments. Its systems serve industrial, public safety, space, defense, and transportation sectors, including applications in drones/UAVs, robots/UGVs, and TV broadcast.

1 investor

Simr provides a platform for running and managing high-fidelity engineering simulations, using automation (which it calls SimOps) to simplify traditional simulation workflows. It serves engineers working in product design and manufacturing.

1 investor

Simreka provides an AI-driven R&D platform for chemicals, materials, and manufacturing companies, using virtual experimentation and simulation to accelerate product formulation and process discovery. The platform includes a domain-specific language model trained on chemical patents and technical literature, with deployment options for cloud or on-premise environments.

1 investor

SimScale provides a cloud-native, AI-driven engineering simulation platform that lets engineers run multiphysics simulations (structural, fluid, thermal, and electromagnetic) through a web browser. It combines simulation solvers with AI agents and predictive models for design engineering teams across industries such as automotive, energy, and industrial equipment.

1 investor

Sindri Materials develops a scalable production process for ultra-high-quality monolayer graphene with low contamination and defects. Its initial application is graphene support grids for cryo-electron microscopy used in drug discovery, vaccine development, and disease research, with longer-term aims in electronics, energy storage, and structural materials.

1 investor

Sinergy Flow is a deeptech startup developing a low-cost, sustainable redox flow battery for long-duration (multi-day) energy storage, using earth-abundant materials such as sulfur to support renewable energy penetration. Based in Milan, Italy, its modular and scalable technology targets long duration energy storage aligned with circular economy principles.

1 investor

Singlera is a biotech company specializing in in vitro diagnostic reagents and instruments. The company focuses on research and development with a team of experts holding advanced degrees.

1 investor

Singletto develops Oxafence Active Protection™, a materials-applied antimicrobial technology integrated into protective materials such as masks, using photodynamic approaches to enable active microbial inactivation during use. The company licenses its platform technology to healthcare, operational, and emerging markets where traditional antimicrobial solutions have proven limited.

1 investor

SingulaNet develops and operates content technology services. The company designs platforms and tools for content creators and publishers.

1 investor

Sinntaxis is a pharmaceutical company developing mGluR5 negative allosteric modulators as a drug therapy to restore brain function and support recovery after stroke and brain injury. Spun out of Lund University, it runs a preclinical discovery platform for stroke recovery research and licensed IP on this treatment approach.

1 investor