Deep Tech Startups

Shape Biopharmaceuticals develops innovative immunotherapeutic drugs and vaccines using synthetic vaccine technology and bio-nanotechnology for clinical-stage applications. The company serves the biopharmaceutical industry with next-generation therapeutic solutions.

1 investor

Shared Spectrum Company (SSC) develops Dynamic Spectrum Access (DSA) radio technology and spectrum sharing solutions for wireless communications, including work for programs such as DARPA's XG Program. Founded in 2000, it provides RF propagation and spectrum sharing engineering services to government and commercial customers and partners.

1 investor

Sharpa builds humanoid robotics hardware, including the D01 system that combines a dexterous Wave hand, 7-DoF arms, whole-body tactile E-skin, and a teleoperation system for complex physical tasks. Its technology targets real-world manipulation requiring high precision, agility, and tactile sensing.

1 investor

Sharp Therapeutics develops a small molecule drug platform designed to treat genetic diseases more affordably and quickly than current biologics and gene therapies. The company targets patients and payors seeking faster, scalable alternatives to existing genetic disease treatments.

1 investor

SHC Therapeutics is a pre-clinical biopharmaceutical company developing bio-therapeutics using its proprietary Genomic RNA Packaging Enhancement (GRPE) platform to deliver targeted therapies. It aims to create personalized and precision treatments across a range of disease areas, with a lead candidate in the pre-clinical phase.

1 investor

Shield Bio is a precision medicine company developing a platform for third-generation nanopore DNA sequencing that produces results in under a minute in clinical settings. It is initially applying the technology to infectious disease treatment and sepsis diagnostics.

1 investor

UFORCE builds autonomous defense systems, including combat-proven platforms used in the Russia-Ukraine War for missions in contested environments. The company pairs advanced AI software with hardware and is expanding from Ukraine to NATO allies and the U.S.

1 investor

Shifamed develops and brings to market medical devices designed to address unmet clinical needs in healthcare. The company accelerates medical technology innovation through collaboration between experts from within and outside the medtech industry.

1 investor

Shift provides end-to-end development of autonomous maritime systems, covering mission design, hardware assembly, sensor and payload integration, field deployment, and long-term sustainment. It serves governmental agencies, defence organizations, technology companies, and research initiatives for maritime security and environmental monitoring operations.

1 investor

Shimber develops an iridescent, wood-based coating that produces structural color through a cellulose nanostructure, without pigments or petrochemicals. The bio-based, microplastic-free coating is aimed at fashion, luxury, design, and architecture applications such as textiles, accessories, interior décor, and installations.

1 investor

Shiratech is a Germany-based software engineering partner that develops embedded systems, safety-critical applications, AI-powered solutions, and multi-sensor data fusion. It offers complete product development and team-extension engineering services across industries, including defense and aerospace-related domains.

1 investor

A psychedelics research organization that discovers new psychoactive substances and develops compounds and delivery systems for therapeutic use, continuing the work of Dr. Alexander "Sasha" Shulgin. It also operates as an educational organization in the field of psychedelics.

1 investor

SI Solutions provides technical engineering services including advanced engineering, inspection and testing, and digital monitoring and analytics for high-stakes industrial operators. It serves markets such as nuclear, energy services, process industries, infrastructure, pipeline integrity, and renewables.

1 investor

Siddhalayam is a spatial AI platform that generates immersive 3D environments and simulations from natural-language prompts using generative AI and NVIDIA GPU acceleration. It targets developers, studios, and enterprises seeking to create production-ready virtual worlds at scale.

1 investor

Siden Beam is a streaming-native platform built for aircraft, integrating content delivery, bandwidth optimization, and passenger engagement analytics into a single architecture for onboard environments. It serves airlines as an alternative to traditional in-flight entertainment or caching solutions.

1 investor

Sidereus Space Dynamics was a space technology research and development company operating in Italy and Europe. It has concluded its R&D program and is now in discussions with industrial partners regarding the potential acquisition of its technology assets, infrastructure, and intellectual property.

1 investor

Sidewalk Infrastructure Partners (SIP) invests in and develops businesses and projects focused on energy and digital infrastructure systems, including virtual power plants and data centers. Its portfolio includes Renew Home, an operator of residential virtual power plants, and Verrus, a data center developer.

1 investor

Skyworks Solutions designs and manufactures semiconductor products, including amplifiers, front-end modules, filters, RF passives, timing/clock devices, isolation components, diodes, and power management ICs. Its chips serve cellular, Wi-Fi, automotive, industrial, and infrastructure applications across 5G, IoT, and connectivity standards.

1 investor

Silicon Genesis Corporation (SiGen) develops layer transfer and NanoTec technologies used in solar and semiconductor manufacturing, licensing its intellectual property and supplying tools for the semiconductor, display, and optoelectronic markets.

1 investor

Sigetronics develops semiconductor devices and materials, including APD sensors for LiDAR, bio-medical sensors for wearables, and GaN power FETs and RF HEMTs for 5G, radar, and charging applications. It also operates an M-FAB foundry with a portfolio of IPs serving 5G/6G mobile communications and related electronics markets.

1 investor

Teledyne DALSA designs, develops, and manufactures high-performance digital imaging products and semiconductor products and services, with core competencies in specialized integrated circuits, electronics, software, and semiconductor wafer processing. Established in 1980, it operates internationally as part of Teledyne Technologies.

1 investor

SigmaSense builds a semiconductor and software sensing platform that converts raw signals into high-precision, real-time data for applications including battery health monitoring (Onboard EIS), touch and touchless human interfaces, and industrial systems. It serves markets such as battery and power, automotive, medical, IoT, and consumer devices, and licenses its sensing technology to semiconductor makers like NXP.

1 investor

SignalEdge Solutions develops RF sensor hardware and proprietary DSP algorithms for signal detection, classification, and geolocation, used in applications such as Comint/Elint detection, radars, RF seekers, and electronic warfare. Its low-SWaP sensors are designed to be mounted on ground and airborne platforms for defense and signals-intelligence use.

1 investor

SignalUp provides AI-powered full-service hardware product development, covering electrical and mechanical engineering, firmware, and manufacturing. It targets inventors and entrepreneurs who have hardware product ideas but little or no in-house engineering team.

1 investor