Deep Tech Startups

UC3 (UltraConductive Copper Company Inc.) is an energy-tech engineering startup developing copper/graphene composite meta-materials that increase copper's conductivity by embedding nano-layers of graphene, for use in ultra-conductive wires and foils. Its target applications include electric power grids, electric vehicles, electronics, and data networks.

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URZ3 Energy is a uranium exploration company identifying strategic assets to meet rising demand for nuclear energy. The company serves the clean energy sector, particularly supporting sustainable AI data centers and North American energy independence.

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Valaurum manufactures the Aurum, a small verifiable unit of physical gold made from micro-layers of gold sealed between polymer, marketed as an investment product, collectible, and legal tender currency. It serves precious metals investors and mints through channels including national mint distributors and retail stores across North America, Europe, and Asia.

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Valliscor is a technology-driven chemical manufacturer specializing in high-value fluorine-containing compounds for the pharmaceutical, semiconductor, and polymer industries. The company produces pharmaceutical starting materials, semiconductor etchants, and specialty monomers leveraging proprietary and licensed technologies.

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Vaztec develops advanced internal combustion engine technologies, including rotary valve cylinder heads that replace conventional poppet valve systems, and licenses these technologies to product manufacturers. Its core offering aims to improve engine efficiency, power density, and lifespan while reducing vibration and noise across a range of engine applications.

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Ventiva develops ionic (electrohydrodynamic) thermal management modules that provide targeted, fanless cooling for electronic systems such as ultra-thin laptops, edge AI devices, and datacenter components. The technology has no moving parts and frees up board space for additional memory, storage, or battery, serving hardware and system designers building compact, high-performance AI systems.

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Verasonics builds research ultrasound platforms (including the Vantage NXT and Vantage Research systems) that let users acquire, store, process, and analyze ultrasound data with programmable SDKs and real-time raw channel data access. It serves researchers and product developers across fields such as biomedical, material sciences, earth sciences, and biometrics, and its systems are for laboratory research/development rather than approved clinical use.

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Veridify develops quantum-resistant security solutions for constrained IoT and operational technology devices across industrial, building automation, critical infrastructure, and automotive sectors. The company provides embedded security toolkits and the DOME platform for secure device onboarding, authentication, and ownership management across globally distributed low-resource edge devices.

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Verismo is a biopharmaceutical company founded by the inventors of Kymriah, the first FDA-approved CAR T cell therapy, developing next-generation CAR T therapies using KIR receptor technology to address limitations in first-generation approaches.

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Verseon uses quantum physics-based modeling combined with AI to design novel small-molecule drug candidates for major human diseases. Its pipeline targets conditions including cardiovascular disease (anticoagulants), diabetic vision loss, multidrug-resistant cancers, and solid-tumor metastasis, with candidates ranging from preclinical to clinical stages.

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VERSES builds Genius, an AI system based on active inference and "digital brain" architecture that models cause-effect relationships and quantifies uncertainty to produce explainable, domain-specific predictions. It targets enterprise and financial services clients, including Fortune 500 companies and asset managers, offering cognitive AI as an alternative to generic machine learning tools.

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Vesicor develops precision-engineered cellular microvesicles that deliver p53 mRNA to cancer cells using a non-viral, immune-silent platform, aiming to restore tumor suppression in advanced solid tumors. Its lead candidate, ecm-RV/p53, and broader platform are designed for oncology therapeutics and multiple payload types.

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Vibrant provides nondestructive testing (NDT) inspection technology using patented PCRT (Programmable Chromatic Resonance Technology) for manufacturing quality control. The system uses vibrational pattern recognition to detect flaws and material defects in parts across industries including aerospace, turbine, and automotive manufacturing.

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Villya Pharmaceuticals develops water-soluble reformulations of existing drugs using a patented carbohydrate-loading technology, including liquid praziquantel, a topical gel for Female Genital Schistosomiasis, second-generation erectile dysfunction medications, and oral peptide therapeutics such as semaglutide and insulin. The company focuses on improving solubility, gastric stability, and delivery of pharmaceuticals to enable oral administration of otherwise injectable medicines.

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Vitanova Biomedical develops cancer treatments based on a proprietary light-activated intracellular acidosis (LAIA) therapy that uses upconverting nanoparticles and deep-penetrating light to induce cancer cell death. The company operates in the biomedical and oncology therapeutics space.

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Volcano Platforms is an early-stage startup building physics-based computational fluid dynamics (CFD) simulation software that automates first-principles engineering simulations and generates synthetic data for AI. Its VOLCANO ScaLES product targets engineering and simulation workflows.

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Vuzix develops waveguide optics, display systems, and OEM platforms for device makers, and designs and manufactures enterprise AI smart glasses for warehouse, field service, healthcare, and industrial use. Its products and OEM programs serve defense, enterprise, consumer, and medical markets.

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Whooshh develops technology solutions for fish handling, monitoring, and passage in aquatic environments. The company serves water utilities, fish hatcheries, and environmental agencies managing fish populations and migration.

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Widetronix develops ultra-low power sensors enabled by betavoltaic power sources based on wide bandgap semiconductor materials, serving applications requiring autonomous, maintenance-free power. The company commercializes silicon carbide betavoltaic technology spun out from Cornell University.

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XDemics develops cell culture and biomanufacturing technologies for generating mammalian cells at high densities for advanced therapy production. The company's HDCR platform and related products enable researchers and GMP facilities to produce T cell, stem cell, and viral-based therapies with improved quality and consistency.

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xMEMS Labs designs MEMS-based semiconductor components for audio and related applications. The company develops solid-state products aimed at consumer and device manufacturers.

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YAN Engines is developing technology to improve the efficiency of the internal combustion engine, drawing on the team's automotive and power-generation R&D background. The company works in engine and powertrain engineering for the energy and automotive sectors.

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Yatiri Bio applies unbiased proteomics, deep learning, and patient-derived cellular models to cancer drug discovery, building a molecularly defined patient landscape to identify ideal patient subsets for novel therapeutics. It offers computational tools such as its ProteoBrowser data portal and ProteoModels cellular systems for oncology drug developers working on personalized medicine.

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Yost Labs develops sensor fusion firmware and 3-Space inertial sensors (combining gyroscope, accelerometer, and magnetometer) that determine real-time orientation for motion tracking. Its products, ranging from surface-mount PCBs to wireless full-body motion capture systems, serve applications in virtual reality, drones, autonomous vehicles, robotics, medical rehab, and athletics.

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