Deep Tech Startups
7,090 companies tagged Deep Tech, with their investors and founders.
New Frontier Bio is a biotechnology company with a cross-functional management team experienced in start-ups, science, strategy, and M&A across healthcare, biotechnology, and cosmetics.
0 investors
New Sapience builds "sapiens," a deterministic machine intelligence based on world-model directed-graph knowledge structures rather than machine learning or symbolic AI, used to automate decision-making and monitoring for critical infrastructure. It targets mission-critical operations across CISA-defined critical infrastructure sectors, offering expert human-in-the-loop judgement plus quantum-secure communications.
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NewSight Reality develops optical and augmented reality technology, drawing on ophthalmic and photonic engineering expertise. The company's work spans optical instrumentation and display devices.
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Next Wave Partners is a venture studio and fund investing exclusively in companies at the intersection of autonomy, physical AI, and infrastructure, including agentic AI, robotics, edge computing, and intelligent infrastructure. The firm provides patient capital, embedded operational support from experienced executives, and founder-aligned revenue-based capital structures designed for deep tech companies.
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ni2o is a US-based company developing AI and brain-computer interface (BCI) technology to detect and treat neurodegenerative diseases such as Alzheimer's, Parkinson's, and ALS. Its products span software for ultra-early detection, a wearable EEG-like headcap for monitoring and non-invasive stimulation, and a minimally invasive brain micro-implant.
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NioCorp is a mining and mineral extraction company developing the Elk Creek Project to produce niobium, scandium, magnetic rare earths, and titanium.
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Nirrin builds optical instruments and analytics software for bioprocess teams to generate measurement data across development and manufacturing workflows. Its systems are designed for deployment in regulated biopharma production and quality environments.
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Nona Technologies makes RECOVER, a modular retrofit system that uses an MIT-patented Ion Concentration Polarization process to clean and recycle cooling-tower blowdown water, reducing water waste and cooling OpEx. It targets data centers and industrial facilities facing water constraints on their cooling systems.
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Norsk Titanium manufactures aerospace-grade titanium preforms using additive manufacturing (RPD® technology) for structural applications in aerospace and defense. The company operates three facilities across the U.S. and Norway with ITAR-registered production capability and serves aerospace, defense, and industrial customers requiring repeatably qualified components.
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NovaSolix develops a solar energy device that uses nanoscale antenna arrays to convert the full solar spectrum (UV to IR) directly into electrical power, aiming for higher power density and efficiency than traditional photovoltaics. It targets manufacturers and integrators seeking high-output solar for applications needing maximum output in minimal space.
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Nudge develops technology focused on improving how people interact with their brains, and conducts related studies.
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Nuvvon develops next-generation battery technologies, focusing on polymer and battery materials research and development. The company works on solid-state battery materials and energy storage technologies.
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NV Therapeutics develops non-viral gene therapies designed to be safe, effective, and scalable. The company targets a new generation of genetic treatments for disease.
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Nxbeam is a technology company operating in the semiconductor and communications space. The about page profiles its leadership rather than detailing a specific product.
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Objective Biotechnology develops neurotechnology tools for cortex-wide optical access and neural recordings in unrestrained rodent models, along with automated microinjection systems for large-scale genetic manipulation and embryo microinjection. Its products serve researchers working with biological systems.
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Oboro Labs develops catalyst technology to mass-produce cyclic polymers, materials aimed at applications such as low-friction coatings, lightweight electronic materials, and drug delivery systems. The company, spun out of research at the University of Florida, works to commercialize these polymers for use across manufacturing and consumer product industries.
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Ommo develops spatial tracking technology that provides 3D pose and position data in complex real-world environments, including safety-critical medical settings. Its proprioceptive tracking layer is designed to complement and correct perception systems by delivering ground-truth pose data through contact and interaction.
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OmniAb develops transgenic animal platforms engineered to generate human antibodies for therapeutic drug discovery, serving biopharmaceutical researchers and drug developers.
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OneSky is a UAS Traffic Management (UTM) company building airspace assessment, operations, and traffic management software for the aviation industry, serving drone operators, drone manufacturers, and airspace authorities. Spun out of Analytical Graphics, Inc., it has deployed and validated its technology with organizations such as the FAA, NASA, the Civil Aviation Authority of Singapore, and Airservices Australia.</parameter> <parameter name="founders">[{"full_name": "Robert Hammett", "title": "CEO"}]
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OpenBench runs AI-enabled structure-based virtual screening to identify small molecule hit series for biotech drug discovery programs, screening large compound libraries and charging only for hits that meet a client-defined profile. It works with clients' own assays and CROs, offering a success-driven model where collaborators purchase resulting IP outright.
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Ophirex is a biotech company developing varespladib, an investigational oral capsule intended to treat snakebite envenomation by inactivating a key venom toxin found in most snake species. The drug is designed as a portable, field-administered rescue treatment to bridge the gap before hospital antivenom.
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Optex Systems manufactures optical sighting systems and assemblies for U.S. Department of Defense applications, with products installed on military vehicles including the Abrams, Bradley, and Stryker platforms. The company also produces periscopes, rifle sights, surveillance sights, and night vision optical assemblies for military and defense contractors.
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Optomec builds additive manufacturing systems, including 3D metal printers and 3D printed electronics equipment, for industrial production, repair, and prototyping. Its customers include manufacturers, academic institutions, and government organizations.
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Oragenics develops treatments for concussion and traumatic brain injury, focusing on clinical development of therapeutic candidates. The company combines neuroscience expertise with healthcare operational leadership to advance solutions for brain injury treatment.
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