Deep Tech Startups

Basilard BioTech develops Celletto, a nanomechanical (mechanoporation) gene delivery platform that inserts genes directly into the nucleus of cells without viral vectors, aimed at cell and gene therapy (CGT) developers and manufacturers. The technology targets the gene-delivery bottleneck in engineering cell-based therapies, offering an alternative to viral, chemical, and physical delivery methods.

4 investors

Becoming.bio develops robotic systems that sustain mammalian development outside the body, combining closed-loop hardware for metabolic regulation with AI models that predict how organisms develop and respond to intervention. The company works at the intersection of biology, robotics, and machine learning to study developmental processes and disease.

4 investors

Bioflyte provides chemical and biological threat detection solutions for critical infrastructure and business operations, enabling organizations to monitor, identify and respond to bio/chem threats. The company serves government agencies, critical infrastructure operators, and other organizations responsible for security and safety.

4 investors

BiomX builds a portfolio of defense and security companies through subsidiaries, partnerships, and acquisitions, focusing on detection systems, aerial technologies, and infrastructure security. It targets field-proven products serving homeland security, critical infrastructure, border, transportation, and public safety needs within a Detection, Analysis, and Response operational chain.

4 investors

bitBiome provides contract analysis and collaborative research using single-cell genome sequencing technology for microbial samples. The company serves clients in biotech and related manufacturing sectors in Japan and the U.S.

4 investors

BLUU develops marine cell-based ingredients derived from cultured fish cells for personal care, health, and food applications. The company uses proprietary bioprocessing workflows grounded in peer-reviewed research to produce ethically sourced, traceable compounds that replicate results unattainable through land-based agriculture.

4 investors

BosonQ Psi (BQP) develops BQPhy, a simulation software that integrates quantum computing with high-fidelity engineering simulations such as computational fluid dynamics. The company builds tools for engineering and computational analysis, drawing on expertise in quantum computing, CFD, and related emerging technologies.

4 investors

Branch Technology uses patented digital fabrication and additive manufacturing to enable architects and designers to construct complex structural designs at scale. The company combines robotics, prefabrication, and computational design for the built environment and construction industry.

4 investors

Warhead designs and manufactures advanced explosive ordnance systems for autonomous weapons platforms and drone applications. The company serves U.S. defense and military customers with transport-safe binary explosives and 3D-printed warheads for counter-UAS and autonomous systems.

4 investors

BTRY develops ultra-thin, solid-state thin-film batteries using a scalable production technology. Its energy storage solutions target IoT, medical technology, and consumer electronics applications.

4 investors

Cailabs designs and manufactures photonics products based on its proprietary Multi-Plane Light Conversion (MPLC) technology for laser applications, serving the industrial, telecommunications, and space and defense sectors. The company builds products for industrial lasers, telecom networks, and satellite-to-ground laser communications.

4 investors

Cambridge GaN Devices (CGD) designs ICeGaN gallium nitride power transistors that integrate temperature control and gate reliability features and can be driven by standard silicon gate drivers. The devices target power electronics applications such as automotive/EV inverters, offering higher switching frequency, lower losses, and improved energy efficiency versus silicon.

4 investors

CamGene Therapeutics develops RNA-based medicines, including mRNA, siRNA, and antisense oligonucleotides delivered via lipid nanoparticles, to treat the underlying cellular dysfunction that causes hearing loss. The company aims to modulate protein expression for regeneration and protection of cells in the cochlea as an accessible mass-market therapeutic.

4 investors

Canopy Aerospace & Defense designs and manufactures specialized materials and components for aerospace, defense, and space applications, including composites, thermal protection systems, and machined parts. The company operates as an integrated platform providing end-to-end solutions from design through production and sustainment.

4 investors

Captivate develops a proprietary Metal-Organic Framework material and Vacuum Pressure Swing Adsorption process for low-energy, cost-effective carbon dioxide capture and separation in industrial applications including biogas, geothermal, and cement production.

4 investors

Caravel engineers proteins into scalable industrial "protein machines" for applications including critical minerals recovery, carbon capture, and industrial processes. The company develops a protein engineering platform aimed at reducing the time and cost of scaling proteins for industrial use.

4 investors

Carbice manufactures aligned carbon nanotube-based thermal management products for aerospace, defense, and industrial power applications. The company operates the world's largest vertically aligned carbon nanotube production facility, located in Atlanta, Georgia, with additional operations in France and California.

4 investors

Cascade Bio develops improved biocatalysts (enzymes) that are reusable, long-lasting, and offer higher output and a wider operating window compared to conventional options. Its products target industrial and commercial biocatalysis applications.

4 investors

CB Therapeutics builds a yeast platform for biosynthesis of molecules including psychedelics, cannabis, and alkaloids that are difficult to source through conventional methods. The company serves pharmaceutical and specialty chemical manufacturers.

4 investors

Cellanome develops a live-cell analysis platform using CellCage technology to create controlled microenvironments that enable researchers to observe cell behavior and molecular changes over time. The platform generates structured multimodal data for life sciences researchers and biopharma companies focused on oncology, neuroscience, immunology, and aging research.

4 investors

CellChorus develops a visual AI platform called TIMING that performs high-throughput dynamic analysis of single cells, measuring cell activation, killing, and movement over time for biopharmaceutical research. The company serves biopharmaceutical companies and therapy developers seeking to understand cellular function and phenotype.

4 investors

Cellid is a fabless company developing AR glasses displays (waveguides) and spatial recognition engines for next-generation devices. It works with major domestic and international manufacturing partners to build a production ecosystem for mass-producing its waveguides.

4 investors

Chiral develops electron spin alignment technologies and applications based on the CISS effect to reduce resistivity and overpotential waste, enabling sustainable and higher-performance solutions.

4 investors

Civil Maps provides high-definition mapping and localization technology, producing high-fidelity point cloud data with 15–20 cm absolute accuracy. Its mapping coverage spans the United States, Europe, and Asia.

4 investors