Deep Tech Startups

Arpeggio Bio is a pharmaceutical company that uses AI and high-throughput RNA-sequencing to develop drugs targeting transcription factors, including historically "undruggable" proteins such as NRF2, TEAD, and GPX4. Its lead program targets IO-resistant melanoma, and it has worked on rare disease and inflammation programs through partnerships.

6 investors

Artificial Agency is an AI company applying reinforcement learning to build agent technology for video games, drawing on research and gaming-industry expertise. Its team develops game technology and AI agents for the gaming industry.

6 investors

AscendArc develops small, high-throughput geostationary (GEO) satellites that are volume-produced to lower costs and speed deployment for satellite communications. The company applies LEO-style scalable manufacturing to GEO orbit and holds multiple U.S. Air Force contracts.

6 investors

Asimov develops a computer-aided design platform for genetic engineering, enabling designers to program living cells by applying abstraction, standardization, and modeling to biology. The company serves genetic engineers and biotechnology researchers building engineered biological systems.

6 investors

AstronauTx is a biotechnology company focused on drug discovery and development for neurodegenerative and neuroinflammatory diseases, working across small molecules and biologics. Its programs target areas such as Alzheimer's disease, sleep, and other CNS disorders.

6 investors

Astroscale develops on-orbit servicing solutions, providing end-to-end services covering mission licensing, spectrum acquisition, insurance, and operations to support the circular space economy. It serves satellite and space mission operators globally.

6 investors

AttoTude develops optical interconnect technology for data centers to support artificial intelligence and exascale computing applications.

6 investors

Auki builds spatial computing technology that makes the physical world browsable, navigable, and searchable, with the goal of making physical spaces accessible to AI. Its work spans robotics capabilities including locomotion, manipulation, and perception (converting camera and sensor input into spatio-semantic observations).

6 investors

Auterion develops products and services around open standards for autonomous systems technology, contributing to open source projects and supporting academic institutions.

6 investors

AviadoBio is a gene therapy company developing adeno-associated viral (AAV) treatments for neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). It is a spinout from King's College London research focused on the genetics and molecular biology of these diseases.

6 investors

Azafaros is a clinical-stage biopharmaceutical company developing small-molecule therapies for severe rare genetic metabolic disorders, including GM1/GM2 gangliosidoses, Niemann-Pick type C disease, and other conditions. The company's lead program, nizubaglustat, is currently in Phase 3 trials.

6 investors

Azumo develops low-power display technology, specifically reflective LCD systems and front light panels that reduce energy consumption for device screens. The company serves manufacturers building displays for consumer electronics and other applications requiring efficient visual systems.

6 investors

Baebies develops multifunctional syndromic diagnostic testing using proprietary digital microfluidics, integrating molecular, immunoassay, chemistry, and coagulation testing into a single compact platform (FINDER) that runs on small-volume samples. Its products serve hospitals, clinics, pharmacies, and decentralized care settings for patients of all ages, having started with newborn and pediatric diagnostics.

6 investors

Bagel Labs develops distributed training methods for diffusion models using commodity hardware across heterogeneous systems. The company builds decentralized diffusion model architectures that replace single large models with ensembles of smaller expert models, enabling training of generative models for robotics, video, and world modeling on non-homogeneous GPU infrastructure.

6 investors

Basetwo provides AI solutions that optimize manufacturing operations for Fortune 500 companies in pharmaceuticals, specialty chemicals, and personal care. The software helps manufacturing teams improve productivity, speed, and resilience across operations in Europe, Asia, and North America.

6 investors

Bedrock Ocean manufactures autonomous underwater vehicles (AUVs) and a cloud platform that collect high-resolution seafloor mapping and monitoring data for offshore energy, maritime infrastructure, defense, and scientific research sectors.

6 investors

Bellatrix Aerospace develops and manufactures advanced propulsion systems for satellite deployment and orbital missions. The company serves space operators by offering plasma thrusters and chemical propulsion alternatives that achieve higher performance and longer operational life at lower cost than incumbent technologies.

6 investors

BiomX builds a portfolio of defense and security companies through subsidiaries, partnerships, and acquisitions, focusing on detection systems, aerial technologies, and infrastructure security. It targets field-proven products serving homeland security, critical infrastructure, border, transportation, and public safety needs within a Detection, Analysis, and Response operational chain.

6 investors

Blue Energy develops scalable small modular reactor (SMR) technology to deliver nuclear power at scale. The company focuses on removing economic barriers to nuclear infrastructure deployment for utilities and data centers seeking clean, reliable baseload energy.

6 investors

Bluecore develops floating nuclear power systems, drawing on expertise from aerospace, maritime, and nuclear industries to build next-generation energy infrastructure.

6 investors

Blumind is a Canadian deep-tech startup developing all-analog AI neural network architectures for energy-efficient edge AI computing. It builds and licenses its AMPL analog compute technology on standard CMOS process technology, aimed at low-power AI applications.

6 investors

Brelyon develops headset-free virtual displays using optical and computational techniques to create 3D depth and panoramic imagery for gaming, entertainment, and enterprise applications. The technology delivers a cinema-like experience in a standard monitor form factor.

6 investors

BSPKL develops catalyst coated membranes (CCM) for electrolyzers and fuel cells with significantly reduced precious metal loading. The company serves manufacturers of hydrogen generation and fuel cell systems through novel membrane-catalyst layer manufacturing technology adapted from semiconductor processes.

6 investors

Cambridge Terahertz commercializes terahertz sensor technology based on MIT research, delivering compact on-chip radar systems that use non-ionizing radio waves to create 3D images analyzed by AI. The technology miniaturizes capability previously available only in airport scanners for enterprise security and imaging applications.

6 investors