Deep Tech Startups

HUBER+SUHNER Polatis develops optical circuit switches for fiber-layer automation, offering configurations from 8x8 to 384x384 ports. Its POLATIS switches are used for test lab automation, network monitoring, photonic fabrics in AI data centers, and photonic cross connects for quantum applications.

1 investor

Polku Therapeutics is a preclinical CNS drug discovery company developing small-molecule therapies that modulate the PREP–PP2A axis to target tau aggregation and neuroinflammation in neurodegenerative diseases. Its lead program pursues disease-modifying treatments for tauopathies and related conditions such as Parkinson's disease, starting with orphan tauopathy indications.

1 investor

Pollen Sense is an airborne particle intelligence company whose APS400 sensors use optics, AI, and environmental science to measure and identify pollen, mold, dust, smoke, and other bioaerosols in real time. It provides sensor networks, licensed allergen datasets and APIs, indoor air investigations, and the consumer Pollen Wise allergy app for public health programs, municipalities, researchers, facilities, and allergy sufferers.

1 investor

Polycam is a cross-platform 3D capture and editing software company that provides tools for scanning, mapping, and processing 3D content. The company serves creators, builders, and businesses seeking accessible 3D capture technology.

1 investor

Polymark develops a patented nanolayer polymer film that gives physical objects a molecularly unique, non-cloneable identity, paired with a QR-based Polycode and cloud software for smartphone verification. It serves use cases including ID cards and documents, luxury goods, art provenance, aerospace and medical supply chains, and anti-counterfeiting across public and private sectors.

1 investor

Polymatech Electronics designs and manufactures opto-semiconductor and compound semiconductor products used in devices such as smartphones, tablets, satellite communications, and GPS. It positions itself as an Indian compound semiconductor manufacturer serving businesses with customized applications and large-scale production.

1 investor

Polymathic AI develops foundation models and machine learning for scientific data, aiming to build models that reuse shared concepts across disciplines for researchers. Its work includes an AI agent that determines organic molecular structure from raw experimental NMR data by treating the task as a constrained search over chemical space.

1 investor

Polyphron builds a verification layer for drug discovery that combines physically engineered arrays of human tissue with AI simulations of that tissue, letting models test therapeutic predictions against living human biology. It trains frontier models to explore and reproduce human tissue biology, aiming to provide a human-relevant substrate for validating AI-generated interventions.

1 investor

Polyplus (a Sartorius company) develops FectoVIR-LV, an animal-component-free transfection reagent for producing lentiviral vectors in suspension HEK-293 cells at large manufacturing scale. It targets cell therapy producers, including those making CAR-T and other allogenic or autologous therapies, in the biomanufacturing sector.

1 investor

Pontifax is an investment firm that establishes and partners with biotech and healthcare companies across multiple therapeutic areas and development stages, providing hands-on portfolio management and strategic guidance.

1 investor

Pontoon is a decentralized cross-chain bridge that uses a proof-of-stake relayer network to enable trustless, gas-less token transfers across multiple blockchains. It targets liquidity fragmentation by letting users provide liquidity across chains and earn rewards in the platform's native token.

1 investor

POP Biotechnologies develops nanomedicine platform technologies based on patented porphyrin-phospholipid (PoP) liposomes, targeting infectious disease, oncology, and chronic diseases. Its work includes a rapid vaccine development platform and targeted chemotherapy approaches activated by laser light.

1 investor

PoroTech develops MicroLED semiconductor materials and manufacturing processes for next-generation display and lighting applications. The company specializes in gallium nitride (GaN) and III-V semiconductor innovations aimed at advancing the commercial adoption of MicroLED technology.

1 investor

POROUS develops a non-invasive ultrasound-based medical device for quantitative bone quality assessment and osteoporosis detection. The company, spun off from Charité Universitätsmedizin Berlin, serves clinical and veterinary markets to improve bone health diagnostics and patient outcomes.

1 investor

Doublepoint developed gesture-control technology that uses biometric signals and subtle hand movements to let people control devices through natural gestures, offered via products like WowMouse and the Touch SDK. The company was acquired by Oura and is integrating its gesture technology into future Oura products.

1 investor

Portable PPB provides detectORE™, a CSIRO-invented portable XRF-based technology for detecting low-level (parts-per-billion) gold concentrations on-site from RC/AC, core and soil samples. It serves gold exploration and mining companies globally, offering same-day in-field gold results to speed up discovery and development.

1 investor

Portal Innovations provides early-stage capital, laboratory space, and operational support to scientists and entrepreneurs building companies in emerging innovation ecosystems. The company connects breakthrough researchers with investors and corporate partners through deep university relationships and in-house scientific expertise.

1 investor

Positronic provides an evaluation service for physical AI and robotics models, running a customer's policy or checkpoint on its own real robots and simulators to return video and time-to-milestone scores for each run. It serves robotics and AI teams that need to compare model checkpoints under controlled, blind conditions with scoring fixed in advance.

1 investor

Potsdam Science Park is a science and business park in the Golm district of Potsdam, Germany, hosting Max Planck and Fraunhofer institutes, University of Potsdam faculties, and research-focused companies in biotechnology, pharma, diagnostics, health, and new materials. Its site management provides services and support for scientists, students, startups, investors, and companies in the Berlin-Brandenburg region.

1 investor

Potter Global Technologies develops fire and life safety technology intended to protect people, property, and critical infrastructure. The company operates through a group of businesses focused on life safety solutions for global markets.

1 investor

Power Planet develops drilling and well operations technologies, hardware innovations, and integrated energy systems for oil and gas field development. The company combines AI/ML, hardware engineering, and operational expertise to extend technical capabilities in drilling, completing, and fracturing operations.

1 investor

PowerDown Semiconductor develops low-power circuit technology that reduces dynamic switching power in computing systems, enabling higher performance without increased thermal output. The company targets semiconductor and systems designers working on power-constrained applications.

1 investor

PowerLight Technologies (a dba of LaserMotive, Inc.) develops optical power beaming systems that convert electricity into high-intensity light, transmit it over long distances, and reconvert it to usable power at a specialized receiver. The company is developing transmitter and receiver systems to wirelessly charge aerial drones, targeting defense, telecom, and digital infrastructure applications.

1 investor

Powerus builds unified systems architecture and hardware for autonomous operations in defense and critical infrastructure. The company operates as a manufacturing and integration platform serving military branches and allied nations through specialized operating companies focused on mission systems, heavy-lift platforms, and maritime autonomy.

1 investor