Deep Tech Startups

Autonomous Marine Systems (AMS) builds the DATAMARAN, an autonomous multi-hulled sailing platform for long-dwell ocean sensing and data collection. The company serves customers in offshore energy, offshore wind, coastal monitoring and defense sectors, and was acquired by JASCO Applied Sciences in July 2024.

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Aveta Biomics develops cancer therapeutics based on Orthologous Molecular Structures (OMS), metabolites from organisms with orthologous genes and processes, combined using an evolutionary-biology-based platform. Its drugs aim to treat and prevent cancers while addressing tumor heterogeneity and drug resistance.

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Axcend builds compact, portable HPLC (high-performance liquid chromatography) instruments, including the Focus LC line with automated sampling, real-time reaction monitoring, and multi-wavelength UV detection. Its analytical chemistry systems serve pharmaceutical, chemical, and educational customers for lab and production-line analysis.

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AxonVR develops haptic technology for virtual reality, including HaptX Skin (a microfluidic haptic textile that simulates touch, texture, and temperature), HaptX Skeleton (a force-feedback exoskeleton), and a HaptX SDK for developers. It works with enterprise clients to build immersive VR experiences with realistic touch feedback.

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Axtra3D develops advanced additive manufacturing (3D printing) solutions using proprietary optoelectronics-based technologies for industrial and commercial applications. The company manufactures the X1 Series of printers powered by its patented Hybrid PhotoSynthesis technology.

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Azak develops modular, self-propelled wheel technology that converts standard containers and platforms into motorized vehicles. The company serves customers seeking alternative mobility solutions for cargo and material handling.

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Badwater Alchemy develops produced water treatment solutions using nano materials to remove contaminants from oil and gas operations at significantly lower cost than thermal desalination. The modular systems recover over 80% of water while reducing brine disposal volumes and potential seismic risks.

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Baker Street Scientific operates a data intelligence platform that uncovers hidden associations and patterns within large datasets to support decision-making across organizations and industries. The company uses an associative and predictive engine to transform raw data into actionable intelligence for both common and complex business decisions.

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Balboa Geolocation develops geolocation technology and AI/ML systems, serving first responders, government agencies, and enterprise customers. The company leverages expertise from aerospace, defense, and sensor technology sectors.

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Beartooth manufactures ruggedized mesh networking radios designed for secure off-grid communication in tactical and extreme environments. The devices integrate GPS tracking, use military-grade encryption, and connect to smartphones via USB for situational awareness and data transmission.

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Bectas Therapeutics is a biotech company operating in the therapeutic development space. The page features CEO Ronan O'Hagan discussing biotech industry insights, leadership, team building, and organizational culture.

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Bell Copper is a publicly traded mineral exploration company (TSXV: BCU; OTCQB: BCUFF) focused on discovering large-scale porphyry copper systems in Arizona. Its assets are the wholly owned Big Sandy Project and the Perseverance Project, a joint venture with Cordoba Minerals, both located in northwestern Arizona near Kingman.

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BioConsortia discovers and develops microbial biological products for agriculture, using microbial engineering and field validation to create seed-applied and soil-directed solutions that enhance crop productivity and sustainability. The company serves global agriculture stakeholders seeking biological alternatives to synthetic inputs.

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Bitbison builds a system of record that captures a complete, causal history of activity across systems — from developer workstation through build to production — to enable runtime security detection, policy enforcement and audit. It works at the kernel, networking and storage layer to capture events with low overhead for infrastructure security teams.

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Bluespec develops tools and IP for hardware and embedded systems developers, with a focus on RISC-V technology for core evaluation, software development, acceleration, and verification. The company also maintains an open source family of RISC-V cores.

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bluShift Aerospace develops MAREVL modular hybrid rocket engines powered by a proprietary non-toxic biofuel, used for boosters and small launch vehicles as well as dedicated suborbital flights. The company serves researchers and technology-demonstration customers, offering microgravity research time and STEM education programs through its launches.

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BNNT Materials produces boron nitride nanotubes (BNNTs) in various as-grown and refined forms for nanotechnology research and development applications. The company operates in the advanced materials and nanotechnology sector.

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Botlink develops drone software, including the Botlink app, used across industries such as agriculture, mining, roofing, and public safety. The company focuses on autonomous systems and drone technology.

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Boulder Imaging provides machine vision inspection software and systems for manufacturing and industrial quality assurance across industries including aerospace, defense, flooring, banknotes, and wind energy. The company leverages advanced imaging technologies to enable real-time inspection and precision manufacturing solutions.

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Bravolta is a technology company developing solutions for the industrial sector, drawing on engineering and scientific expertise.

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BrickBio develops protein and antibody-drug conjugate (ADC) therapeutics using its Evolved tRNA Localization (ETRNAL) platform, which incorporates synthetic amino acid conjugation handles at specific sites in a protein backbone via mammalian expression systems. The company targets pharmaceutical and biotech applications, aiming to produce more stable and efficacious conjugated biologics, including multi-payload conjugates.

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Brilliant Light Power develops the SunCell, a power-generation device that converts hydrogen from water into a claimed more stable form called "Hydrino," producing plasma, heat, and light that is converted to electricity via photovoltaic and magnetohydrodynamic methods. The company targets stationary, motive, thermal, and defense power markets and plans to lease its units to customers.

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Bruker provides preclinical imaging solutions for research across oncology, neurology, cardiology, and other disease areas, serving academic institutions and pharmaceutical researchers.

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CAGE Bio is a clinical-stage biotech developing localized topical treatments for dermatology, inflammation, and immunology conditions using its proprietary deep eutectic ionic liquid platform. The technology enables small and large molecules such as proteins and nucleic acids to penetrate the skin, aiming to match the efficacy of systemic drugs while avoiding their side effects.

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