Deep Tech Startups

Optics11 develops fiber-optic sensing systems designed for harsh operating environments, providing ultra-sensitive, low-power monitoring of temperature, pressure, strain, and vibration. Its solutions serve defense, energy infrastructure, and industrial operators for asset monitoring and security.

2 investors

Ora develops loudspeaker membranes made from graphene (GrapheneQ) that reduce harmonic distortion, lower power consumption, and increase sound pressure levels. Its acoustic material targets audio hardware makers across applications including gaming headsets, smartphones, laptops, home audio, automotive, and hearing aids.

2 investors

Orange Grove Bio is a biotech venture firm that builds and backs cell therapy and immuno-oncology companies, forming subsidiary companies (subcos) such as Ipinovyx and DomainOne Therapeutics. It operates in the biopharmaceutical and life sciences investment space.

2 investors

Orbion provides a computational platform for protein engineering that characterizes sequences, ranks stabilizing mutations, predicts construct expression, and generates experimental protocols to filter designs before lab synthesis. The platform serves biotechnology researchers and protein engineers working to optimize protein candidates for expression and function.

2 investors

Orbital Industries is an "AI Industrial" company that develops physical AI models—including AI-accelerated simulators and autoresearch agents for advanced materials—to speed up the design and manufacture of hardware products. Its first commercial products are new molecular classes for high-density GPU cooling in AI data centers, with plans to expand into energy, semiconductors, and other materials and machines.

2 investors

Orbital Sidekick operates hyperspectral imaging satellites and provides data analysis for commercial operators in energy, mining, and agriculture, as well as environmental monitoring and national security applications. Its offerings help detect operational risks, support sustainability initiatives, and expand situational awareness through georectified hyperspectral intelligence.

2 investors

Organovo develops regenerative medicine therapies using bioprinting technology to treat serious liver diseases. The company serves the pharmaceutical and biotech sectors with innovative therapeutic approaches based on decades of leadership expertise in life sciences.

2 investors

Orienspace develops specialized wireless data link communication systems for airborne platforms operating in complex environments. The company manufactures compact, low-latency transceivers that enable long-range command, telemetry, video, and image transmission for high-speed aircraft and unmanned aerial systems.

2 investors

Origin AI develops WiFi-based sensing technology that uses existing wireless signals and AI analytics to detect and monitor human motion indoors, including presence, falls, vital signs, and sleep patterns. The company targets whole-home monitoring applications in the AI sensing and IoT category.

2 investors

Orikine Bio develops engineered cytokines called Foldikines™ to reprogram immune responses for treating autoimmune and inflammatory diseases. The platform uses bi-specific cytokines designed to target specific immune cells with precision while minimizing off-target toxicities.

2 investors

OSCP builds inertial sensors for autonomous systems that operate in environments without reliable satellite signals, such as tunnels, mines, and underwater settings. The company manufactures these sensors in Canada without US-controlled content.

2 investors

Outlier is developing a reusable, uncrewed satellite platform that provides access to microgravity in orbit with safe return of payloads to Earth. It serves researchers, in-orbit manufacturers, and government programs across pharma, biotech, and advanced materials, with a platform planned to launch in 2028.

2 investors

Outrun Therapeutics is a preclinical biotech developing small molecule E3 ligase inhibitors to stabilise tumour suppressor proteins for treating cancer and other diseases. Its lead programme targets an E3 ligase in hard-to-treat solid tumours.

2 investors

Outset is a New Zealand-based deep tech venture firm and R&D campus that helps founders build and scale frontier technology companies globally, providing facilities, community, and capital. It runs Momentum, an opportunity fund backing New Zealand deep tech companies as they scale.

2 investors

OVER builds a decentralized spatial intelligence platform that trains Large Geospatial Models on 3D mapping data to support robotics, machine perception, and spatial AI, and offers AI-powered tools for creating and publishing AR/XR experiences tied to real-world locations. It serves both enterprises and Web3 participants through a DePIN model where users can own spatial domains and share revenue from B2B XR publishing.

2 investors

Owlo develops patented optical imaging technology that enables non-invasive, real-time 3D imaging deep within biological tissue. The company targets applications in IVF, drug discovery, and ophthalmology.

2 investors

Oxford Biomedica is a biopharmaceutical contract development and manufacturing organization (CDMO) specializing in cell and gene therapies, lentiviral vector technologies, and bioprocessing solutions. The company provides manufacturing, development, and technical services to clients developing advanced therapies.

2 investors

Oxford Ionics develops trapped-ion quantum computers using proprietary Electronic Qubit Control technology, designed for businesses to deploy quantum computing applications. The systems are manufactured through standard semiconductor supply chains and support field upgrades as computational needs scale.

2 investors

Oxi-Tech Solutions develops a water sanitation system using Pulse Oxidation, a process that uses water and low-voltage electricity to eliminate bacteria and viruses without chemicals. The company positions its technology as a chemical-free alternative for producing pathogen-free water, with applications noted in the Agri-Tech sector.

2 investors

Pacific Biosciences develops long-read DNA and RNA sequencing platforms and kits for genomics research, including whole genome, targeted, epigenetic, and RNA sequencing applications. The company serves research institutions, clinical laboratories, and diagnostic organizations in genomics and life sciences.

2 investors

Pacific Channel is a venture capital and investment firm focused on identifying, advancing, and investing in deep-tech startups in the sectors of food, health, and the environment. The firm partners with founders and portfolio companies to support commercialization and growth across multiple geographic markets.

2 investors

PAGE Technologies provides real-time environmental monitoring using solid-state sensors and AI analytics to deliver continuous visibility into chemical, physical, and biological signals for operational and regulatory compliance.

2 investors

PainTEQ develops medical devices and implants for sacroiliac joint dysfunction, offering solutions ranging from biologicalbone allografts to titanium implants as alternatives to injections or fusion surgery. The company focuses exclusively on sacroiliac joint treatment for patients and physicians.

2 investors

Palatial converts real objects and environments into physics-accurate, verifiable 3D simulations via an API, generating physics-ready assets at scale to train physical AI and foundation models. Its outputs are formatted for robotics simulators such as NVIDIA Isaac Sim, Newton, and MuJoCo, serving robotics and machine learning teams.

2 investors