Deep Tech Startups

Corisma develops a fully implanted transcatheter mechanical circulatory support system for advanced heart failure patients, designed to bridge acute and chronic care with improved quality of life. The device eliminates the driveline and uses wireless, catheter-based technology to replace current standard-of-care treatment options.

1 investor

Coronal develops plasma arc additive manufacturing technology that melts wire to print near net shapes from difficult alloys for use in extreme environments. It serves energy, aerospace, marine, and defense customers needing advanced manufacturing and material development for high-performance components.

1 investor

Coros Space builds integrated compute platforms that process data onboard spacecraft in orbit, addressing the downlink bottleneck where satellites generate more data than they can transmit to Earth. It develops radiation-tolerant, high-performance computing hardware for space systems and mission-critical applications.

1 investor

Cortex Fusion Systems develops nuclear energy technology using ultrafast lasers, including a compact high-repetition-rate fusion source, a hybrid fusion-fission reactor that drives a subcritical fission blanket with fusion neutrons, and a laser-based uranium enrichment process using broadband lasers to produce HALEU and LEU. The company targets grid-scale nuclear energy and fuel production, with technology intended for co-location at industrial sites.

1 investor

Cortical Dynamics builds the BARM (Brain Anaesthesia Response Monitor), a device that detects the effect of anaesthetic agents on brain activity using algorithms based on a physiological model of brain electrical activity, to help anaesthetists keep patients optimally medicated. The system is intended for hospital and clinical anaesthesia use.

1 investor

Cortirio develops a wearable infrared brain imaging headset for rapid detection of stroke and traumatic brain injury. The device provides portable, on-site diagnosis in under two minutes for clinical use.

1 investor

Cortisonic develops AI hardware based on reservoir computing using arrays of interconnected nanomechanical oscillators (phononic circuits) that process information through vibration and sound. The company targets low-power, high-performance machine learning as an alternative to traditional deep learning models.

1 investor

Cosma develops precise, repeatable and scalable underwater mapping and environmental survey solutions, focused on benthic biodiversity monitoring and subsea obstacle identification. It serves subsea project clients using underwater robotics, navigation, data collection, AI and marine biology expertise, and is based in France.

1 investor

COSMIIC develops active implantable medical devices, including its Networked Neuroprosthesis (NNP) modular implant platform that stimulates muscles and records signals to restore function for people with disability and disease. It also provides resources to academic researchers to help translate implantable device concepts into systems tested in first-in-human studies.

1 investor

Hyperweb provides an end-to-end TypeScript ecosystem for building and deploying full-stack blockchain applications, executing smart contracts via a JavaScript VM. Part of the Interchain JavaScript Stack, it targets web3 developers with infrastructure, client tools, and smart contract frameworks for cross-chain development.

1 investor

Cosmos Innovation develops a machine learning platform for optimizing recipe development in semiconductor and solar process engineering. It targets manufacturers and developers of next-generation semiconductor technologies.

1 investor

Cothera Bioscience is a clinical-stage biotech company developing cancer therapeutics aimed at previously undruggable oncology targets, using a translational platform based on synthetic lethality and protein degradation pathways. Its lead candidate is zotiraciclib, an oral CDK9 inhibitor for recurrent high-grade glioma with IDH1/2 mutations.

1 investor

Countable Labs (formerly Enumerix) develops Countable PCR, a DNA quantification technology that provides absolute target counts at single-molecule resolution as an alternative to qPCR, digital PCR, and NGS. Its genomics tools serve scientists working in biomarker analysis, gene therapeutics, and clinical diagnostics.

1 investor

CovalX provides mass spectrometry-based analytical services for biotherapeutic development, including epitope mapping, de novo sequencing, and monoclonal antibody characterization. It serves pharmaceutical and biotechnology companies across Europe and the United States, supporting drug discovery and development.

1 investor

covolv.ai develops an energy-efficient embedded AI/ML platform and vehicle operating system that enables L2+ to L4 autonomous driving on a single compute unit for vehicle manufacturers. It targets OEMs, Tier-1 suppliers, and technology partners, aiming to make autonomous and driver-assistance features available across mass-market vehicles.

1 investor

COXEM designs and manufactures scanning electron microscopy (SEM) equipment, including tabletop and full-size electron microscopes along with accessories such as ion beam polishers, sputter coaters, and detectors. Its products serve life science and materials science research and analysis.

1 investor

CPP Wind provides wind engineering services, including full-scale wind load measurement and testing for structures such as solar PV racking systems. It publishes technical resources like white papers on best practices for measuring wind loads.

1 investor

Crafton Biotechnology is a biotechnology company developing mRNA medicines based on its own RNA manufacturing, delivery, and synthesis technologies, with a focus on high-purity mRNA and clinical translation.

1 investor

Craxel builds Black Forest, a data infrastructure platform that consolidates an organization's fragmented data into a unified, AI-ready knowledge asset and enables real-time contextualized queries and knowledge graphs at scale. It is aimed at large enterprises with massive data challenges and can be deployed on cloud, on-premises, or edge infrastructure with built-in zero trust security.

1 investor

Crayonic develops embedded crypto-biometric technology for secure digital identity solutions, combining machine learning, cryptography, and secure microprocessors. The company serves organizations in sensitive markets requiring core digital identity protection for people and assets.

1 investor

Creatcomm Technology develops WiFi, 5G, and IoT wireless products including 5.8G/60GHz microwave links, WiFi bridges and access points, consumer WiFi6 routers, and cloud-based management systems. It serves telecom operators, wireless video surveillance projects, and SMB coverage needs, with R&D centers in Shanghai and Nanjing and manufacturing in Kunshan.

1 investor

Create it REAL develops 3D printing technology and proprietary slicing software for sustainable, on-demand production in the orthopedic and prosthetic industries. It provides 3D printing systems and materials that let businesses produce customized products without needing prior additive manufacturing expertise.

1 investor

CREmedical develops brain sensing and neuromodulation technology, including its Tripolar Concentric Ring Electrode (TCRE) sensors, Tripolar EEG (tEEG) signal acquisition, and Transcranial Focal Electrical Stimulation (TFS). The platform cancels muscle and noise artifacts in real time and delivers Laplacian-based physiological signals for applications such as detecting biomarkers and modulating GABA and Glutamate.

1 investor

Creoir provides embedded, on-device Voice AI technologies — including automatic speech recognition, text-to-speech, and speech signal enhancement — that operate without cloud connectivity. It serves civilian industries and the defence sector, integrating voice user interfaces into products such as defence command-and-control systems, critical communications devices, and industrial automation and robotics.

1 investor