Deep Tech Startups

Coherent Biopharma (Tongyi Pharmaceutical) is a biopharmaceutical company developing its proprietary Bi-targeting XDC (bi-XDC) conjugate drug platform to make previously undruggable targets treatable, with a focus on oncology. It has a pipeline of first-in-class candidates and clinical trials across multiple cancer indications, operating in China, the U.S., and Australia.

1 investor

Coinplug (CPLABS) builds blockchain-based infrastructure and technology, working with financial, telecom, and government organizations on digital identity and related projects. Founded in 2013, the company holds numerous patents and serves partners primarily across Asia.

1 investor

Colimit offers a coding agent for formal spec-driven development, guiding users to write formal specifications without prior experience, check specs for logical bugs, and generate code by combining compilers with LLMs. It also verifies that the generated implementation matches the specification.

1 investor

Columbiad Launch Services is a commercial space launch company developing a high-volume Industrial Sounding System based on gun propulsion technology to provide low-cost access to space.

1 investor

Compound Eye builds camera-based sensing and perception technology (VIDAS) that combines AI with classical computer vision to give autonomous machines depth measurement, scene understanding, and positioning without LiDAR or radar. It serves defense, heavy equipment (construction and mining), and automotive applications.

1 investor

CompPair is a Swiss company that develops self-healing (healable) advanced composite materials designed to bring repairability to composite products across sectors such as aerospace. Spun out of EPFL research, its technology supports circular economy practices by extending the life of composite parts.

1 investor

Compular builds physics-based simulation and AI software that predicts material properties, letting R&D teams digitally screen chemical formulations before lab testing. It serves material developers and researchers in chemicals, advanced materials, and battery/electrolyte development.

1 investor

Condenzero develops cryogenics and ultra-high vacuum (UHV) systems for transmission electron microscopy (TEM), including liquid helium cooling technology for TEM instruments. Its products serve scientific research and materials characterization applications.

1 investor

Conexus AI, spun out of MIT research, builds data integration and verification technology grounded in category theory. It serves government agencies, defense organizations, and large financial institutions, with clients including NASA, the U.S. Department of Defense, and Fortune 50 firms.

1 investor

Confluence Labs is an AI research lab developing models that improve learning efficiency, enabling faster scientific discovery with minimal experimental data. The company focuses on accelerating breakthroughs in drug and materials discovery by reducing the number of experiments needed to achieve results.

1 investor

Conjecture develops AI systems using an approach it calls Cognitive Emulation, which translates expert workflows into reusable AI pipelines intended to follow human-like reasoning processes. The company focuses on building AI that is more reliable, interpretable, and safe than systems in the current AI paradigm.

1 investor

Conpart develops and supplies Spherica-branded high-precision polymer microparticles with silver, gold, and nickel coatings for conductive adhesives and gap spacer applications. Its particles serve the electronics and solar energy industries, including uses in microsystems and interconnect materials.

1 investor

Consilium Safety develops safety and fire/gas detection systems, including hydrogen sensor technology and monitoring units for industrial and maritime safety applications.

1 investor

Constellation provides an operations platform designed for satellite fleet management that ingests telemetry data, executes machine learning predictions, and automates decision-making based on operator policies.

1 investor

Control Bionics develops non-invasive neural-signal and physiological-data technology that converts biosignals into decision-ready insights for clinical, rehabilitation, research, sports performance, and assistive communication use. Its products, including speech-generating and eye-gaze AAC devices, serve individuals, clinicians, and organizations and hold FDA, TGA, and CE clearances.

1 investor

Convexia provides AI-powered drug discovery and evaluation software that scans global sources for overlooked drug assets and runs deep in silico simulations across 50+ models to assess binding, toxicity, pharmacokinetics, and immunogenicity. The platform combines AI agents with expert human review to accelerate drug asset evaluation for biotech companies, pharma firms, and venture investors.

1 investor

Coolbrook develops electrification technology for industrial decarbonization, enabling fossil fuel replacement in heavy industries including chemicals, steel, cement, and petrochemicals. The company's RotoDynamic technology can reduce industrial CO2 emissions by up to 30% when powered by clean energy.

1 investor

CooliBlade develops advanced thermal management solutions for industries including renewable energy, telecommunications, and EV charging infrastructure. The company designs and manufactures cooling technologies aimed at reducing energy consumption and improving system reliability.

1 investor

Cooling Photonics develops passive radiative cooling materials that reflect solar radiation and reduce heat buildup on outdoor industrial equipment such as electrical cabinets, power electronics, and solar inverters. The materials are designed for companies seeking to improve asset reliability, reduce maintenance costs, and lower operational emissions without active cooling systems.

1 investor

Copenhagen Atomics is a Danish nuclear energy company developing thorium molten salt reactors designed for mass manufacturing, sold to nuclear power plant owners as fixed-price 100 MWth reactor units with fuel supply and maintenance. Founded in 2014 and based near Copenhagen, it has built prototype reactors and targets low-cost electricity, with its first test reactor planned for 2028.

1 investor

Coral Innovations develops selective nanomaterials for water remediation and resource recovery, addressing pollution from oil spills, nutrient runoff, and heavy metals. The company serves industries and water utilities seeking effective, cost-efficient solutions for environmental compliance and water ecosystem preservation.

1 investor

Corisma develops a fully implanted transcatheter mechanical circulatory support system for advanced heart failure patients, designed to bridge acute and chronic care with improved quality of life. The device eliminates the driveline and uses wireless, catheter-based technology to replace current standard-of-care treatment options.

1 investor

Coronal develops plasma arc additive manufacturing technology that melts wire to print near net shapes from difficult alloys for use in extreme environments. It serves energy, aerospace, marine, and defense customers needing advanced manufacturing and material development for high-performance components.

1 investor

Coros Space builds integrated compute platforms that process data onboard spacecraft in orbit, addressing the downlink bottleneck where satellites generate more data than they can transmit to Earth. It develops radiation-tolerant, high-performance computing hardware for space systems and mission-critical applications.

1 investor