Deep Tech Startups

Cambrium designs and produces enzymes, polymers, and peptides using a molecular design platform and biological systems, aiming to create high-performance materials. It serves multiple industries including textiles, automotive, cosmetics, and construction where material performance is a priority.

6 investors

Carbon Engineering is a Direct Air Capture (DAC) technology company, founded in 2009, that develops systems to capture large volumes of CO2 directly from the atmosphere. It operates as a subsidiary of Occidental's Oxy Low Carbon Ventures, advancing core DAC technology at its Innovation Centre while sister company 1PointFive handles commercial-scale plant deployment.</parameter> <parameter name="founders">[]

6 investors

Biomemory develops DNA-based data storage systems for data centers, offering an alternative storage tier optimized for long-term archival, density, and energy efficiency. The company manufactures synthetic DNA storage cards and servers that integrate with existing multi-tier data center architectures to reduce infrastructure costs and environmental impact.

6 investors

Cellineobio develops cell engineering and bioprocess technology platforms. The company serves biotech and pharmaceutical research and manufacturing customers.

6 investors

Clearpath Robotics builds unmanned vehicles and robotics platforms aimed at making robotics research and development easier for its customers. It serves R&D groups and researchers working on robotics applications, positioning itself in the robotics hardware sector.

6 investors

Cloudline develops autonomous airships powered by solar and battery technology for carbon-free aerial operations. The company targets applications requiring extended range and endurance with reduced operating costs compared to traditional aviation.

6 investors

Conceivable builds AURA, a robotic automation platform that automates manual IVF laboratory procedures using physical AI, aiming to increase accessibility and affordability of in-vitro fertilization treatments.

6 investors

Conception develops stem cell technology to create functional reproductive cells in the laboratory, enabling in-vitro gametogenesis as a solution for individuals facing biological and medical fertility barriers.

6 investors

Concerto Bio generates large-scale ecological datasets on microbial communities and uses them to develop microbe-based consumer health products for applications such as skincare, chronic disease, and nutrition. Its approach combines high-throughput experimental data generation with predictive modeling to make microbial communities engineerable.

6 investors

Cordance Medical is developing NeuroAccess, a non-invasive medical device that uses low-frequency focused ultrasound and microbubbles to reversibly open the blood-brain barrier at targeted sites, enabling drug delivery and blood-based biomarker measurement. It targets brain diseases including brain cancers, Alzheimer's, Parkinson's, and epilepsy, and its device received the FDA's Breakthrough Device Designation.

6 investors

Correlia Bio develops the PIXI platform, a benchtop automated immunoassay system that uses proprietary microfluidic gel technology to quantify proteins from samples as small as 1 uL. Aimed at pharmaceutical and proteomics researchers, it offers a faster alternative to traditional ELISA for protein measurement in laboratory workflows.

6 investors

Cosmic Shielding develops radiation-shielding technology that adapts commercial off-the-shelf (COTS) electronics — including AI-capable GPUs, sensors, and cameras — for reliable operation in space. It serves spacecraft and satellite engineers building compute and data systems for orbital missions.

6 investors

CREW is a Yale spinout that adds calcium carbonate (ground limestone) to wastewater treatment plants to intensify biological treatment, cut chemical costs, and permanently remove carbon dioxide. It serves municipal and industrial wastewater utilities while also selling verified carbon removal to corporate carbon buyers.

6 investors

D-Wave is a quantum computing company offering both annealing and gate-model systems for solving optimization, simulation, and modeling problems. It serves enterprises and researchers through cloud access, developer tools, and professional services for applications in areas such as materials simulation and machine learning.

6 investors

Deep Genomics develops AI-based biological foundation models to identify drug targets and design molecules, aiming to speed up drug discovery. Its platform combines lab-in-the-loop workflows, training datasets, and screening technologies to find candidates for developing new medicines.

6 investors

eGenesis uses gene editing and genome engineering to develop porcine donor animals for cross-species organ transplantation, addressing organ failure treatment and transplant supply constraints.

6 investors

Element Biosciences develops biological analysis platforms and DNA sequencing tools for scientists and research institutions. The company serves a global customer base across 40+ countries in the life sciences and genomics industry.

6 investors

Enlaza Therapeutics develops covalent protein therapeutics using its War-Lock technology, which incorporates proprietary unnatural amino acids into protein drugs so they form irreversible covalent bonds with disease-related targets. The company applies this synthetic biology platform to engineer biologics with improved efficacy and safety for treating cancer and other serious diseases.

6 investors

Ethos Space develops technology to build and operate spaceports and infrastructure on the Moon using in-situ lunar resources, including construction material (Durandal), onsite propellant production (Prometheus), and materials for space-based data centers. The company also publishes research reports on lunar and planetary resources such as silicon, water, critical minerals, and helium-3.

6 investors

FairCraft develops lab-grown leather produced from cells and proteins through a material discovery platform, offering an animal-free alternative with low environmental impact. The company creates cell-based materials that brands can fine-tune for touch, feel, and transformability properties.

6 investors

Fauna Bio applies AI and computational analysis to its proprietary biobank of data from extreme mammals such as hibernating species to identify drug targets that are conserved across species including humans. The biotech company focuses on discovering novel therapeutics for human diseases based on evolutionary and genomic insights.

6 investors

Ferveret develops advanced cooling technology for data centers and computing infrastructure, using subcooled boiling methods derived from nuclear reactor engineering. The company serves data center operators and AI/HPC infrastructure providers seeking power-efficient cooling solutions.

6 investors

FluxWorks develops magnetic gearing technology for motion systems, replacing traditional mechanical gears with contactless magnetic solutions. The company serves automation, robotics, and space industries with its Celestial Gear product.

6 investors

Flyability builds collision-tolerant indoor drones, including its flagship Elios 3, designed to navigate confined and hazardous spaces to collect inspection data for industries such as energy, wastewater, and mining. The Swiss company, an EPFL spin-off, provides drone technology for industrial inspection worldwide.

6 investors