Deep Tech Startups

Booster Therapeutics develops small-molecule medicines that directly activate the cell's 20S proteasome to restore protein quality-control and clear disease-causing proteins, using its structure-based DGRADX platform combining high-throughput screening, X-ray crystallography, and computational tools. The company is building a multi-disease pipeline initially focused on neurodegenerative diseases.

1 investor

Borea Therapeutics develops gene therapy delivery technologies based on a proprietary AAV conjugation platform targeting neurological and genetic diseases. The company serves the therapeutic biotechnology market with precision neuronal targeting and advanced delivery strategies.

1 investor

Bornea Dynamics offers innovation, research and development, and rapid prototyping services, along with training programs.

1 investor

Bosonic is developing computing and hardware infrastructure aimed at giving innovators access to advanced computational resources for testing and building ideas. The company's public messaging focuses on connecting people to hardware and computation, though the page provides limited concrete product detail.

1 investor

Boson develops quantum-classical hybrid algorithms for accelerating complex engineering simulations, enabling faster product launches and reduced computational costs for organizations using high-performance computing.

1 investor

Boston Micromachines develops MEMS deformable mirrors, MEMS grating modulators, and adaptive optics software for controlling and shaping light. Its photonics products serve researchers and defense contractors in astronomy, microscopy, laser communication, laser research, and retinal imaging.

1 investor

An AI company associated with scientist Tomáš Mikolov, whose research contributions include algorithms for scaling neural network language models and neural text generation methods used in chatbots.

1 investor

Boulder AI builds edge computing devices that combine sensors, on-device AI inference, and cloud orchestration to analyze high-resolution scenes locally and transmit reduced, contextual insights. The company offers AI-enabled cameras and compute nodes with an enterprise software stack and app store for managing analytics across large fleets of IoT devices.

1 investor

Bow Capital is a University of California ecosystem venture fund that backs early-stage founders building AI for physical, industrial, and biological applications, including robotics, defense, healthcare, and logistics. It sources deals from the UC system's faculty, students, and alumni and runs a UC San Diego incubator focused on national security through science, robotics, and manufacturing.

1 investor

Bohr Quantum Technology develops quantum-native cyberdefense hardware and software for critical infrastructure networks. The company provides an end-to-end quantum network stack with key distribution, deployable nodes, and lifecycle support for quantum-secure communications.

1 investor

Braid develops technology that combines mathematics, physics, and computer science to automate and optimize advanced engineering design, targeting new product development, redesign, and high-performance applications. Its focus includes performance-critical designs and reducing material usage through more ecological, sustainable design.

1 investor

Brain.space develops brain monitoring hardware and a Brain-Data-as-a-Service platform that collects and analyzes standardized brain data to create large mental models for predicting human behavior. The company serves medical and research applications in neuroscience and mental health.

1 investor

Brain-CA Technologies builds an energy-efficient AI learning system based on Cellular Automata and Teleomorphic Computing, replacing heavy neural-network computation with a patented "Estimator" design that removes the Von Neumann bottleneck. Its long-term aim is a hardware "brain-on-a-chip" delivering low-power intelligent computing in silicon, and it has published a book, The Intelligence Shift.

1 investor

BrainVivo develops neurotech that converts MRI brain scan data into algorithmic models to digitize and preserve individual human wisdom. The company serves individuals and organizations seeking access to personalized cognitive intelligence models.

1 investor

Bramante Bio manufactures AI-driven robotic instruments and reagents for life sciences research and manufacturing. The company designs hardware that integrates with modern software stacks and provides direct engineering support.

1 investor

Brandenburg Labs develops spatial audio technology that reproduces lifelike, immersive sound over headphones by simulating how sound propagates in the real world. Its products serve creators, engineers, educators, and home entertainment users.

1 investor

Brandon BioCatalyst funds biomedical development opportunities associated with its Member Institutes, offering investments ranging from AU$500,000 to AU$30 million across stages from proof-of-concept to late-stage technologies. It operates an investment process through an Investment Review Committee, with due diligence handled by Brandon Capital.

1 investor

Brash is a product design and engineering studio that helps entrepreneurs, startups, and established companies develop products from concept to launch. It provides design, engineering, and research services across a range of industries.

1 investor

Breakout is a venture capital firm that has invested for over a decade in science-driven technology companies across biotech, tech-bio, deep tech, and hard tech. It partners with founders scaling scientific innovation and connects them to corporates, strategic partners, and next-stage investors.

1 investor

Breathe Battery Technologies develops physics-based software for battery development, covering cell strategy, simulation and degradation modeling, and adaptive charging that improves performance without hardware changes. It serves automotive and consumer electronics manufacturers such as EV and handset makers to improve battery charging speed, capacity, and lifetime.

1 investor

BridgeComm (BCI) builds free-space optical laser communication systems, including optical ground terminals and stations, modems, and space situational awareness benches for ground-to-space and air-to-ground connectivity. It serves government, space, and telecommunications customers, including U.S. defense and intelligence agencies.

1 investor

Bridger Photonics develops Gas Mapping LiDAR technology and analytics to detect and measure methane emissions from oil and gas operations, helping operators reduce emissions, cut costs, and meet regulatory requirements.

1 investor

BridgeWave develops high-capacity wireless backhaul systems built on its own software-defined RF ASIC chips for the 6-42GHz bands and a four-channel baseband SOC supporting up to 2000MHz of aggregated bandwidth and capacities over 10Gbps. Its systems serve applications such as video surveillance, delivering network backhaul for high-definition streaming to command centers.

1 investor

Bridgewest Ventures is a venture capital firm that invests in and helps build deep tech startups in clean tech, AI/ML, medtech, life sciences, and advanced sensors. It partners with New Zealand founders to commercialize science and connect them to international networks.

1 investor