Deep Tech Startups

BioPhenoMA develops a protein detection technology platform based on its proprietary TN-cyclon (improved enzyme cycling method) to quantify ultra-trace amounts of proteins in real biological samples while preserving their structure and localization. It targets biomedical and life-science researchers analyzing the mechanisms of biological phenomena.

1 investor

Bondwell Technologies develops a protein-based biomaterial platform that uses proteins to create materials for applications across energy, environmental, and medical fields. The company was founded by Texas A&M University scientists and is based in College Station, Texas.

1 investor

Bioretec develops fully biodegradable orthopedic implants for fracture healing and orthopedic surgery, including the RemeOs product line based on magnesium alloy and the Activa line of bioabsorbable implants. The company serves orthopedic surgeons and patients globally across approximately 40 countries.

1 investor

BioSeek builds an AI platform for drug discovery that unifies fragmented biological sources—literature, patents, clinical, and chemistry data—into a connected knowledge graph, with specialist agents that reason across it from disease biology to safety-screened molecules. The software is deployed inside a customer's own infrastructure so proprietary data and tools join the private graph without leaving their environment, targeting enterprise pharma and biotech research teams.

1 investor

Biosortia is a drug discovery company whose Industrial-Scale Microbiome Mining (ISMM) platform extracts community-derived small molecules from the microbiome at kilogram-to-ton scale, using an AI tool (BiosortAI) to prioritize evolutionarily shaped compounds. Its lead program targets obesity and metabolic disease, with expansion into IBD, gut-brain neuromodulation, oncology, pain, and anti-infectives.

1 investor

Bios Partners is a venture capital firm focused on life sciences and biotech investments, providing diligence and portfolio support for clinical-stage and precision medicine companies. The firm combines deep expertise in drug development, pharmaceutical R&D, and equity research for healthcare institutions.

1 investor

Biotitan develops nanotechnology-based surface treatments with bactericidal and virucidal properties for various environments. The company offers tailored turnkey solutions, training, and custom application services.

1 investor

Biotree develops metabolomics and proteomics analysis platforms and services for research institutions and pharmaceutical companies, offering laboratory testing solutions, medical devices, and cloud-based lab information systems.

1 investor

BIRD Aerosystems develops defense technology to protect air, sea, and land fleets, offering aircraft missile protection systems and border surveillance ("border task force") solutions. It provides turnkey programs including design, certification, and installation through its own Maintenance and Repair Organization, serving governments and defense organizations such as the US government, UN Air Operations, and NATO forces.

1 investor

bitsensing develops radar technology, handling the process from design through mass production, and applies automotive-grade radar to connected industries. The company focuses on radar solutions aimed at safety and convenience applications.

1 investor

BitVMX is an open research project building a production-ready implementation of the BitVMX platform and a BitVMX RISC-V processor capable of running RISC-V programs on Bitcoin. It aims to pass the official RISC-V test suite and is developed by contributors from Rootstock Labs and Fairgate Labs.

1 investor

bitvox is a deep-tech company working at the intersection of hardware, software, and artificial intelligence, developing and operating connected physical systems from circuit board to cloud platform. It builds in-house AI models for acoustic and speech processing and covers the full stack—hardware, embedded software, and cloud infrastructure—within one team.

1 investor

Blackbird Laboratories is a nonprofit life sciences incubator that translates university research breakthroughs into venture-ready biotech companies focused on developing new medicines and enabling technologies.

1 investor

Blacksmith Medicines operates a drug discovery platform focused on developing medicines that target human metalloenzymes. The company works on a therapeutic pipeline built around metalloenzyme-targeted drug candidates.

1 investor

Black Sol Nano develops EM Cloak™, a carbon-nanomaterial metamaterial for electromagnetic interference (EMI) absorption that traps EM waves and dissipates them as heat without requiring electrical grounding. The material targets electromagnetic compatibility (EMC) applications, offering thin, lightweight shielding with high thermal conductivity and customizable absorption across a range of frequencies.

1 investor

Black Swan Biotech (BSB) is a biotechnology company developing antisense oligonucleotide (ASO) therapies for Motor Neuron Disease, with a focus on Amyotrophic Lateral Sclerosis (ALS). It uses genomic research to create gene-modulating treatments targeting the genetic drivers of MND.

1 investor

BlackVe designs, produces, launches, and operates space systems for US national security missions, offering end-to-end mission system integration to the Department of Defense and Intelligence Communities. It operates a 30,000 sq. ft. manufacturing and clean room facility for spacecraft assembly, integration, and testing.

1 investor

Bleiz is an independent research lab focused on technology innovation, developing solutions for environmental and health applications. The company positions itself in seed treatment technology.

1 investor

BliNK Biomedical develops a B cell technology, based on the ISAAC and VIVA|Screen platforms, to identify and isolate specific antibody-producing cells for difficult targets from human and other species such as mouse, rabbit, and dog. The company applies this platform to discover rare antibody-secreting cells and identify therapeutic antibodies.

1 investor

Polymarket operates a decentralized prediction market platform where users can bet on the outcomes of real-world events such as sports and elections. It is a news article about the company rather than the company's own website.

1 investor

Blue Fellowship is a 6-week hands-on program for PhDs, postdocs, and research engineers that teaches early company-building fundamentals such as cap table setup, legal, HR, and fundraising, and connects participants with founders, investors, and mentors. It focuses on helping scientists turn deep tech research into ventures across Europe, and charges no fee and takes no equity.

1 investor

Blue Cheetah develops customizable die-to-die interconnect IP for chiplets, offering physical and link layer interfaces that support open standards such as UCIe and Bunch of Wires. Its solutions target AI, high performance computing, and mobile applications across advanced 2D, 2.5D, and 3D packaging.

1 investor

Blue Current develops a fully dry silicon composite anode battery platform using proprietary elastic polymers to increase energy density while avoiding flammable liquids. The technology targets applications such as wearables, electric aircraft, and EV battery packs with higher power, more cycles, and lower cost.

1 investor

Blue Labs develops Blue-JST, a dual reward mechanism designed to balance relationships and utility, focused on building emotional intelligence into AI systems.

1 investor