Data & Infrastructure Startups

Spacenus uses satellite remote sensing and machine learning to monitor agricultural soil and plant health, enabling enterprises to transition to regenerative farming practices that increase carbon storage while maintaining food production. The company serves agribusiness managers and agricultural enterprises seeking to reduce emissions and achieve sustainable operations.

1 investor

Sparsystems converts waste heat from data centers into usable electricity through regenerative cooling systems, reducing grid dependence and emissions. The company offers modular products tailored to different heat temperature ranges and data center configurations.

1 investor

SparkBeyond develops an AI-powered platform that helps organizations identify root causes, discover complex patterns, and optimize business operations by augmenting data with external factors. The platform serves Fortune 500 companies across insurance, financial services, pharmaceutical, retail, and energy sectors.

1 investor

Sparkl provides infrastructure built around per-app "daemons" that expose application logic to both human users (via HTTPS browser apps) and AI clients (via MCP/OAuth) under a shared permission-grant system. Each daemon includes built-in AI capabilities such as structured JSON memory, a per-path file drive, semantic search indexes, and tool-using generative agents.

1 investor

Sparkle operates a modular data platform that integrates and analyses customer data to enable real-time analytics, personalisation, and value-added services such as loyalty, rewards, and targeted offers. It serves businesses in events, retail, travel and supply chain, and hospitality across the UK and US.

1 investor

SparkToro provides audience research software that surfaces the websites, podcasts, YouTube channels, social accounts, search terms, and AI tools a target audience engages with. It helps marketers build personas and turn audience insights into content, SEO, and social strategies.

1 investor

Spatialedge is a data and applied artificial intelligence solutions company that serves customers with complex technical challenges. Based in Stellenbosch, South Africa, the company delivers innovative solutions using advanced technologies and skills.

1 investor

Specie Bio operates BioExchange, an AI-driven platform for finding, matching, and accessing biospecimens and multimodal clinical data from a global network of biobanks, hospitals, clinics, and non-profit institutions. It serves researchers across the R&D lifecycle for uses such as biomarker discovery, diagnostic test development, and training foundation models, with deep oncology and broad disease coverage.

1 investor

Specific Labs captures real workflow data and processes for training dependable AI agents, serving frontier labs and enterprises.

1 investor

Spectramedix develops cloud-based analytics applications for healthcare organizations to improve patient outcomes and reduce care costs. The company serves healthcare systems and networks across North America and globally.

1 investor

SpeeDx develops PCR-based diagnostic tests for sexually transmitted infections that detect pathogens and antibiotic resistance markers, enabling clinicians to make informed treatment decisions. The tests are designed for use with standard laboratory equipment in clinical settings.

1 investor

DTN provides data, weather intelligence, and AI-driven analytics to support operational decision-making in weather-sensitive and volatile industries, including refined fuel distribution and agriculture. Its products offer real-time visibility, pricing, supply chain intelligence, and weather forecasting for producers, fuel operators, and event operations teams.

1 investor

Spexi operates a distributed network of drone pilots (branded LayerDrone) that captures standardized, ultra-high-resolution aerial imagery and turns it into geospatial datasets such as orthomosaics, 3D point clouds, and Gaussian splats delivered via API. Its data serves teams building and training spatial AI, digital twins, and physical AI systems, with applications in mapping, infrastructure inspection, construction progress tracking, and change detection.

1 investor

Spherix Global Insights provides independent syndicated market research and intelligence for pharmaceutical and biotech companies, combining primary research across physicians, patients, and payers with therapeutic expertise and AI-assisted execution. Its data supports commercial decisions and is used in investor reviews and board conversations.

1 investor

SPhotonix develops 5D optical data storage that encodes data inside fused silica glass for high-capacity, long-term archival and active storage. It targets data centers and the AI data lifecycle, positioning its technology as a storage tier between fast drives and deep archive tape.

1 investor

SPICE deploys collateral to curated private credit books using on-chain infrastructure, mirroring real-world collateral to give depositors verifiable guarantees. It provides a data layer for transparent, queryable risk profiles and automatically matches LPs with borrowers based on risk, serving investors and autonomous agents in private credit markets.

1 investor

SPIN UX operates ARCHAIVE, an AI-powered tool that consolidates drawing data scattered across manufacturing organizations and makes it usable, serving manufacturers. The company is a spin-out of STAR UP, Inc. of Kyoto, Japan, which originally built ARCHAIVE and deployed it with Japanese manufacturers.

1 investor

Spirelight designs and delivers custom speech datasets for voice AI and machine learning teams, coordinating recruitment, recording, transcription, QA, rights, and delivery within a documented workflow. It focuses on hard-to-source needs such as regional accents, dialects, multilingual speakers, and noisy recording conditions, working to a written brief and buyer acceptance criteria.

1 investor

archTIS' Spirion offers sensitive data discovery, governance, and protection solutions for enterprises seeking to locate, classify, and safeguard confidential information across their infrastructure. The platform addresses data security and regulatory compliance requirements across various industry sectors.

1 investor

Splits provides permissionless, self-custodied financial infrastructure built on open-source smart contracts, offering subaccounts, treasury management, accounting, payroll, bank transfers, invoicing, and automations. It supports fiat, stablecoin, and crypto payments and exposes an API, CLI, and MCP server so both people and AI agents can operate accounts under cryptographic access rules.

1 investor

SportBoost AI applies artificial intelligence to sports, combining data science with athletic expertise to serve the sports industry and athletes.

1 investor

SportFeeds offers a REST API that turns social media posts from X and Instagram into structured, AI-tagged sports data, including video highlights, trending commentary, and verified player, team, and league social profiles. It targets developers and sports platforms such as fantasy apps, NIL platforms, team apps, and agency dashboards, mapping data to providers like Sportradar, ESPN, and SportsData.io.

1 investor

SportMeme provides a data analytics service called DePosta for evaluating athletes and acquiring new talent, assessing player performance and fair economic value. Its technology develops "Player Impact Metrics" for individual player evaluation and "Player Interaction Metrics" for player compatibility, with research published at academic conferences.

1 investor

Sportradar provides audiovisual services for sports teams, leagues and federations, producing live commentary, interviews, highlight reels and live event coverage in-house, along with OTT streaming solutions. The company works at the intersection of the sports, media and betting industries to help rights holders generate revenue from their audiovisual sports rights.

1 investor