AI & Machine Learning Startups

iScribe builds an EHR-integrated mobile platform with AI-assisted clinical documentation and E&M coding tools for specialty medical practices such as orthopedics and urology. Its products include iScribe AI for automated note generation, iScribe Code Intelligence for coding accuracy and denial mitigation, and iScribe Flex for independent providers.

1 investor

ISE runs end-to-end paid growth for direct-to-consumer brands, managing Meta ads, landing pages, email & SMS, SEO, and TikTok under one team. It bases creative and media decisions on a first-party co-op of ad revenue data shared across hundreds of connected ad accounts, and charges a performance fee only after launching an ad that beats a client's breakeven ROAS.

1 investor

ISeeChange provides a platform where residents report local weather impacts such as flooding and extreme heat, combining these observations with weather data and AI to produce hyperlocal insights. The tool serves cities, communities, and industries to support infrastructure maintenance, emergency management, flood modeling, and climate adaptation.

1 investor

Isengard Industries manufactures production systems that enable allied nations to domestically produce precision-strike and counter-unmanned aircraft systems at scale and lower cost than traditional defense contractors.

1 investor

Sagent modernizes mortgage and consumer lending platforms for banks and lenders with cloud-based loan servicing software. The company processes over 16 million active loans and $2.5 trillion in unpaid principal balance for 40+ mortgage and consumer lending clients.

1 investor

A company that helps sellers and manufacturers capture and enhance product photos to improve their online sales presence. IGO provides e-commerce support services including photo digitization and systems to boost online sales.

1 investor

Isidor builds secure, vertically-integrated data pipelines that convert raw proprietary enterprise data into reinforcement-learning-ready training material for foundation model post-training, fine-tuning, and alignment. It also provides industry-specific benchmarks, agentic evaluations, and verifiers for generative AI outputs on enterprise workflows.

1 investor

Isochronic builds identity and authorization infrastructure for enterprise AI agent deployments, making heterogeneous agents observable, auditable, and controllable at scale. It offers capabilities such as attribute-based access control, behavioral fingerprinting of agents, and just-in-time provisioning for enterprises running autonomous AI agents.

1 investor

isoFoodtrace uses stable isotope analysis to verify food authenticity and detect fraud by confirming product attributes and labels. The company serves food businesses and consumers concerned with supply chain transparency and product integrity.

1 investor

Isolation Bio develops technology and services for accelerated microbial research and discovery. The company offers the Prospector platform for high-throughput microbial screening and cultivation, alongside custom microbial isolation and cultivation services for researchers.

1 investor

isolved provides HR, payroll, and benefits management through a single platform called Workforce Capital Management, serving 200,000 employers across the United States with technology designed for both human and agentic workers.

1 investor

Isomer builds an AI-powered signals layer that reads unstructured claims communications — emails, letters, attachments, and threads — to surface risk signals and reduce manual inbox triage, routing, and data entry before a claim is formally opened. It serves insurance carriers, TPAs, and self-insured enterprises operating in regulated environments.

1 investor

Isospec Analytics provides glycome and metabolome analysis for biomarker discovery, combining liquid chromatography-mass spectrometry with proprietary CIRIS technology and AI to identify molecular signatures beyond current library limitations.

1 investor

Isotopes.ai builds aidnn, an AI analytics platform that uses a team of specialized agents to plan, execute, and verify data analyses for enterprises. It includes a self-learning system (NeoCortex) and a separate verifier agent that reviews every plan, query, and result, with version-controlled analyses shipped through CI/CD.

1 investor

ISR provides inspection systems based on Specular Vision technology that integrate into industrial production lines, along with quality control optimization software. The company serves manufacturing sectors including automotive, glass, and steel production.

1 investor

ISSEN is a real-time voice AI tutor for language learning that engages users in conversational practice across 50+ languages, available 24/7 on desktop and mobile. The app personalizes lessons based on learner goals, style, and proficiency level, offering features like flashcards, grammar lessons, and translation drills.

1 investor

iStaging provides virtual experience tools for brands and real estate, including AI-based property photo enhancement, 360° photography, no-code virtual tour sites, and virtual staging. Its offerings help create immersive digital content to showcase spaces and support marketing and sales.

1 investor

Istra is a quantitative trading firm that builds data-centric algorithms and low-latency technology to trade in financial markets. Its team of researchers and engineers applies mathematics, science, and data analysis to develop trading strategies.

1 investor

iSystems builds artificial intelligence software for industrial operations, including Leaf for optimization and control of industrial processes and Calix, a supply chain AI platform covering demand planning from S&OP to S&OE. It serves manufacturers and industrial companies, using patented Fuzzy-rule control approaches.

1 investor

It'sRapid is an AI-powered content production platform that automates the creation of eCommerce and retail content for consumer brands. The platform connects to product data sources and existing assets to generate ready-to-publish content across multiple channels while maintaining brand consistency.

1 investor

iTAC Software is a technology company operating as part of the Dürr Group with a global presence. The page provides limited information about the specific products or services offered.

1 investor

iTech provides data capture and data entry services using AI-enhanced OCR, machine learning, and RPA to extract and process information from documents. It serves logistics, healthcare, manufacturing, and municipal clients with solutions like freight invoice auditing, sales order automation, insurance eligibility verification, and vital records indexing.

1 investor

Item is an AI-native CRM designed to replace traditional customer relationship management systems, built for high-growth companies and teams in go-to-market operations. The platform integrates data from over 100 tools and enables autonomous AI agents to execute sales, support, and success workflows while keeping teams organized with familiar interfaces.

1 investor

Iterative.ai makes DataChain, a Python-based data management and versioning layer that runs distributed transformations over files in a company's own cloud storage (S3/GCS/Azure), capturing dataset lineage, metadata, and reproducible experiments. It targets AI/ML researchers and data engineering teams at companies from startups to Fortune 500, letting them search, reuse, and recall datasets and LLM/embedding compute rather than recomputing.

1 investor