AI & Machine Learning Startups

Origami Agents provides an AI-driven sales prospecting tool that searches 50+ live sources (Google Maps, social profiles, job boards, company sites, the open web) to build and verify lead lists with company and contact data. It targets sales teams looking to build pipeline, surfacing hiring signals and new sales leadership, and runs outbound campaigns based on recommended "plays."

2 investors

Origin generates spatial molecular maps from patient tumor samples to enable cancer biology research in native tissue context. The platform combines spatial transcriptomics, imaging, and functional perturbation assays on fresh and archived tumors, paired with AI models for drug response prediction and target discovery.

2 investors

Origin AI develops WiFi-based sensing technology that uses existing wireless signals and AI analytics to detect and monitor human motion indoors, including presence, falls, vital signs, and sleep patterns. The company targets whole-home monitoring applications in the AI sensing and IoT category.

2 investors

Ori is an AI platform that aggregates a firm's emails, meetings, CRM, documents, and relationships to automatically generate investment diligence memos, scoring, and decision insights. It serves investment firms by capturing and analyzing founder calls, tracking portfolio milestones and risks, and delivering continuously updated intelligence.

2 investors

ORO is a data-contribution protocol that lets individuals share private data (such as linked social and health accounts) to help train AI models, using privacy-preserving cryptography (zkTLS) and secure compute environments to keep raw data protected. Contributors earn ORO points and token rewards for completing data quests, with on-chain validation tracking their contributions.

2 investors

OrthoBrain provides AI-powered software and operational tools to enable general dentists to deliver orthodontic care, combining technology guidance and products to support treatment from diagnosis through completion.

2 investors

A technology company that develops avatar robots and communication tools to enable people with physical disabilities and mobility constraints to participate in society and work remotely. The company operates in assistive technology and inclusive employment services.

2 investors

Osfin provides automated reconciliation software for payments companies processing transactions across multiple gateways and channels. The platform handles card, UPI, net banking, wallet, and BNPL payments, helping finance and operations teams prevent revenue loss and maintain accurate settlement records.

2 investors

Osmaura provides law firms with AI agents that monitor legal-specific data sources to identify potential demand and run client outreach. It serves law firms in the U.S. seeking a more predictable way to acquire new clients beyond referrals.

2 investors

Osseus builds a permissioned research brain that connects tools and data across R&D teams to surface past experiments, expert knowledge, and next actions. The platform serves technical and research teams in biotech, manufacturing, and similar knowledge-intensive industries by maintaining continuous memory of how work evolved and preventing repeated efforts.

2 investors

Otio is an AI research workspace that uses a dedicated OCR service to convert scanned and image-based PDFs into permanent, queryable sources that can be cross-referenced with other documents and interrogated with cited answers. It targets professionals such as legal teams handling discovery, academic and archival researchers, and compliance workers who need to query piles of scanned documents.

2 investors

OtterTune was a database tuning service, originally a start-up spun out of Carnegie Mellon University. The company is no longer operating.

2 investors

Otto automates back-office workflows for wealth management firms, opening client accounts (ISA, SIPP, general investment) across providers, executing trades, and moving client money into selected products once advice is agreed. Each action is approved, logged, and evidenced against the client record for regulated, enterprise wealth firms.

2 investors

Ourcart is a purchase validation and intelligence platform that captures, verifies, and structures in-store purchase receipts into SKU-level transaction data for CPG brands, loyalty operators, and marketing teams. The platform prevents fraud and enables accurate measurement of campaign performance and consumer insights through verified purchase intelligence.

2 investors

Outerbounds builds a full-stack platform for machine learning and data science, comprising the open-source Metaflow framework and enterprise-grade infrastructure to help data scientists and engineers design, develop, and deploy ML and data science applications. The platform serves data scientists and engineers who work on data-intensive projects across organizations of all sizes.

2 investors

Outfox Health uses AI tools to help American workers and employers reduce healthcare costs by providing transparency and information about healthcare pricing, delivery, and outcomes. The company addresses the information asymmetry in the U.S. healthcare system that has driven costs to over 10% of household income.

2 investors

Outlit is an AI platform that identifies at-risk customers showing early signs of churn and automates customer retention work. It integrates with a company's existing tools to flag churn risk, explain the underlying causes, and assist customer success teams with win-back outreach.

2 investors

OutPoint provides automated media mix modeling (MMM) software that uses machine learning to help advertisers decide how to allocate ad spend across online and offline channels. It models incrementality and economic lift from a company's revenue and cost data, refreshed monthly, to identify the highest-return channels.

2 investors

Outpost operates a "lab-in-the-loop" platform combining high-throughput experiments with machine learning to model the human microbiome and predict how drugs, food ingredients, and formulations interact with microbial ecosystems. It serves drug and ingredient R&D teams with metabolism, toxicity, efficacy, and safety screening to de-risk candidates in development.

2 investors

Outship is a recruiting platform that evaluates engineers by observing how they use AI coding tools to complete tasks, analyzing their problem-solving approach and decision-making process alongside the resulting code.

2 investors

Outstaffer is a global AI-powered recruitment and employer of record (EOR) platform that enables companies to hire, pay, and manage remote employees across borders compliantly without establishing local entities. The platform combines recruitment expertise with scalable technology to connect businesses with international talent while handling compliance and onboarding.

2 investors

OvalEdge provides a data governance platform that integrates cataloging, business glossary, lineage, quality, access control, and privacy compliance. The platform serves organizations seeking to establish data governance foundations and foster data culture across their operations.

2 investors

Ovation Ventures builds AI-powered financial technology that delivers personalized guidance and client intelligence to financial institutions. The platform integrates conversational AI and contextual insights to help banks, credit unions, and wealth firms deepen client relationships and drive growth.

2 investors

OverAI provides a platform with prebuilt modules and customizable components for building production-ready business applications and automations. It serves enterprises seeking to build internal tools faster without sacrificing structure, observability, and governance.

2 investors