AI & Machine Learning Startups

Orkestra provides energy modelling software for commercial and industrial (C&I) solar and battery projects, offering feasibility analysis, configurable system design, pre-loaded tariff and load data, and shareable reporting. It also offers an asset management platform to track energy and financial performance of solar and battery portfolios, aimed at energy consultants and sustainability teams.

2 investors

ORO is a data-contribution protocol that lets individuals share private data (such as linked social and health accounts) to help train AI models, using privacy-preserving cryptography (zkTLS) and secure compute environments to keep raw data protected. Contributors earn ORO points and token rewards for completing data quests, with on-chain validation tracking their contributions.

2 investors

Orq.ai provides an AI gateway that routes and governs an organization's calls to 500+ AI models across 30+ providers through a single API, adding access controls, guardrails, cost attribution, budget caps, and audit trails. It targets AI teams in regulated industries and emphasizes EU data residency and air-gapped, sovereign deployment options.

2 investors

OrthoBrain provides AI-powered software and operational tools to enable general dentists to deliver orthodontic care, combining technology guidance and products to support treatment from diagnosis through completion.

2 investors

A technology company that develops avatar robots and communication tools to enable people with physical disabilities and mobility constraints to participate in society and work remotely. The company operates in assistive technology and inclusive employment services.

2 investors

Osmaura helps corporate law firms identify and pursue new matter opportunities with clients. The platform targets law firm partners seeking business development solutions in the legal services sector.

2 investors

Oso provides visibility and controls for AI agent adoption within enterprises, enabling discovery, monitoring, and enforcement of agent access and behavior. The platform detects policy violations and generates audit logs for agent actions across engineering, product, finance, and sales teams.

2 investors

Osseus builds a permissioned research brain that connects tools and data across R&D teams to surface past experiments, expert knowledge, and next actions. The platform serves technical and research teams in biotech, manufacturing, and similar knowledge-intensive industries by maintaining continuous memory of how work evolved and preventing repeated efforts.

2 investors

Ossprey detects supply chain attacks and malicious dependencies by monitoring code behavior at runtime, identifying packages that scan clean but behave maliciously. It serves engineering teams building software who need runtime security monitoring without slowing development velocity.

2 investors

Otera builds an agentic AI platform that automates complex manual workflows across enterprise systems, addressing inefficiencies in the global enterprise software market. The platform targets enterprise customers seeking to reduce operational friction between disconnected applications.

2 investors

Sapphire Ventures is a venture capital investor that deploys capital through primary fund commitments, co-investments, and secondary positions in early-stage managers focused on enterprise AI companies. The firm targets venture funds backing the next generation of AI-driven enterprises across the US, Europe, and Israel.

2 investors

OTIV develops assisted, remote-control, and autonomous technology for rail freight operations to improve safety and efficiency while reducing carbon emissions and congestion. The company targets freight transportation operators seeking modal shift solutions from road to rail.

2 investors

Otomo Health builds AI voice technology based on large language models to support medical offices, providers, and patients across the care journey. The company focuses on healthcare applications that ease workload for medical professionals and improve the patient experience.

2 investors

OtterTune was a database tuning service, originally a start-up spun out of Carnegie Mellon University. The company is no longer operating.

2 investors

Cyera provides AI-native data security and classification for enterprises, discovering, governing, and protecting sensitive data across cloud, SaaS, and hybrid environments. The platform combines data discovery, access controls, and automated remediation to reduce data risk and enable compliance.

2 investors

Ottimate is an AI-powered accounts payable automation platform that automates the full invoice lifecycle—from coding and routing to approval and payment—for finance teams across industries. The company serves AP managers, controllers, and CFOs looking to reduce manual processes and operational burden.

2 investors

Oumi is a platform for building, fine-tuning, and deploying custom specialized AI models, automating the model development lifecycle including evaluations, data generation, training, and deployment. It serves ML teams, researchers, and enterprises who want to own their model weights and data rather than rely on rented frontier models.

2 investors

Advocate uses AI-assisted technology and a team of disability advocates to help individuals apply for and secure Social Security Disability Insurance (SSDI) benefits. It also works with long-term disability carriers and organizations on SSDI claim processes.

2 investors

Ourcart is a purchase validation and intelligence platform that captures, verifies, and structures in-store purchase receipts into SKU-level transaction data for CPG brands, loyalty operators, and marketing teams. The platform prevents fraud and enables accurate measurement of campaign performance and consumer insights through verified purchase intelligence.

2 investors

OurRitual is a relationship health platform that combines licensed therapists with AI to provide personalized, ongoing support for couples navigating relationship challenges. The platform delivers continuous care and evidence-based guidance beyond traditional therapy sessions.

2 investors

Outfund provides revenue-based financing and fixed-term loans to small businesses and entrepreneurs, offering capital without equity dilution based on real-time analysis of their revenue and cashflow data. The platform serves UK, Spain, and Germany-based businesses generating £10k+ monthly revenue, with funding amounts from £10k to £300k.

2 investors

Outbound AI builds conversational AI agents that automate phone-based administrative work in healthcare, particularly for medical billing and revenue cycle tasks. The platform serves physician practices, healthcare enterprises, and healthcare partners looking to reduce manual administrative labor and improve workforce productivity.

2 investors

Outfindo is an AI company offering guided selling and product data enrichment tools for online retailers, matching products to customer questions to help shoppers select the right items. Its solutions serve e-commerce businesses looking to improve product data management and the shopping experience.

2 investors

Outfox Health uses AI tools to help American workers and employers reduce healthcare costs by providing transparency and information about healthcare pricing, delivery, and outcomes. The company addresses the information asymmetry in the U.S. healthcare system that has driven costs to over 10% of household income.

2 investors