AI & Machine Learning Startups

Spectrexr develops a hand interaction toolkit for spatial computing that enables creators and developers to build lifelike, physics-driven interactions in augmented, virtual, and mixed reality environments. The toolkit works with Unity and Unreal Engine and requires no coding.

1 investor

Spectrm builds conversational marketing chatbots that brands and enterprise marketing teams can deploy across channels such as websites, apps, Facebook Messenger, and conversational display ads without engineering resources. Its platform uses conversational AI and analytics to personalize customer journeys, guide shopping, generate and qualify leads, and collect declared customer data.

1 investor

Spectronix develops multi-sensor monitoring systems using computer vision and AI to detect human behavior and vital signs in monitored spaces. The technology serves security and safety applications in high-security environments through privacy-preserving skeletal visualization.

1 investor

SpeechLink offers Speech Motor Chaining, a tool that generates evidence-based speech sound therapy practice sessions for speech-language pathologists and their clients. It includes PERCY, an AI clinician assistant that provides feedback to learners at home and automatically collects progress-monitoring data for reporting.

1 investor

SpeEdLabs is an ed-tech company offering an AI-powered adaptive learning platform for K-12 students, teachers, and schools, delivered through a School Integrated Program (SIP) that blends with school curricula. It provides foundation and competitive exam preparation for IIT-JEE, NEET, Olympiads, and CBSE/ICSE boards across India.

1 investor

SpeedSize operates a patented AI-based media optimization and content delivery network that compresses images and videos while preserving visual quality for faster load times. It targets high-volume eCommerce and fashion brands, integrating with platforms such as Shopify, Magento, WooCommerce, and BigCommerce.

1 investor

SPEEQO is a Hong Kong company offering scoped research and engineering consultancy, with roots in voice-based emotion analytics.

1 investor

Spellbook is an AI system for contract work that lets legal teams intake, draft, review, and store agreements, running first-pass reviews against a team's standards and enforcing playbooks on every contract. It serves in-house legal teams and law firms.

1 investor

SpendHQ is an enterprise procurement platform that combines spend data analysis, project tracking, performance management, and risk management to help procurement teams execute digital transformation and achieve cost savings, ESG goals, and compliance.

1 investor

SpendRule provides a contract intelligence platform that automates the validation and enforcement of purchased services contracts in healthcare. The platform validates invoices line-by-line against contract terms before payment, identifies savings opportunities, and maintains a centralized record of monitored spend.

1 investor

DTN provides data, weather intelligence, and AI-driven analytics to support operational decision-making in weather-sensitive and volatile industries, including refined fuel distribution and agriculture. Its products offer real-time visibility, pricing, supply chain intelligence, and weather forecasting for producers, fuel operators, and event operations teams.

1 investor

Speqqle combines scientific modeling with AI to analyze material composition and properties across industries using optical spectroscopy data. The company serves large corporations, spectrometer manufacturers, and research scientists.

1 investor

Spexi operates a distributed network of drone pilots (branded LayerDrone) that captures standardized, ultra-high-resolution aerial imagery and turns it into geospatial datasets such as orthomosaics, 3D point clouds, and Gaussian splats delivered via API. Its data serves teams building and training spatial AI, digital twins, and physical AI systems, with applications in mapping, infrastructure inspection, construction progress tracking, and change detection.

1 investor

Spext Labs, based in the United States, runs an online platform for working with recorded audio. Using AI that links speech to its text transcript, the tool lets users transcribe, edit and repurpose voice recordings by editing the text, serving podcasters, marketers and other audio content producers.

1 investor

SphereBio develops individualized cancer immunotherapies using engineered biological vesicles (OncoSpheres™) that capture a patient's own tumor antigens and deliver them into immune cells to train the immune system against cancer. The company combines biotechnology, synthetic virology, and AI to create individualized cancer vaccines manufactured without sequencing in under seven days.

1 investor

Spheres offers hybrid private markets investment strategies across venture capital and private equity, combined with AI-enabled digital family office services for portfolio administration. It serves private wealth clients, targeting under-allocated market segments and multi-strategy exposure.

1 investor

SphereTrax is a music licensing platform that connects artists with filmmakers, advertisers, and content creators seeking licensed music, while providing composers and musicians a community to showcase work and receive fair compensation.

1 investor

Spherical Defense develops an API security platform using deep learning to detect and prevent attacks by identifying anomalies in API traffic patterns. The company serves organizations seeking to protect their applications from API-based security threats.

1 investor

Spherix Global Insights provides independent syndicated market research and intelligence for pharmaceutical and biotech companies, combining primary research across physicians, patients, and payers with therapeutic expertise and AI-assisted execution. Its data supports commercial decisions and is used in investor reviews and board conversations.

1 investor

Spice Labs provides software scanning and cryptographic analysis tools that generate artifact dependency graphs of software systems and assist organizations in managing their transition to post-quantum cryptography. The platform serves development teams and enterprises seeking to understand software dependencies and remediate security vulnerabilities.

1 investor

Spiich is a lead prospecting platform that identifies and enriches qualified prospects matching a company's ideal customer profile, then syncs them directly to CRM systems like HubSpot, Salesforce, Attio, and Pipedrive. It aggregates data from LinkedIn, company websites, news sources, and existing CRM records to automate lead discovery and qualification.

1 investor

Spiking offers trading education and investment strategy training focused on insider trading principles for individual traders seeking to build wealth. The company provides frameworks and foundational strategies to help new traders develop investment approaches aligned with institutional market players.

1 investor

Spin Analytics is a FinTech firm that provides an AI-based platform for credit risk management, targeting Tier 1 and digital banks to accelerate the development, validation, and deployment of regulatory credit risk models.

1 investor

Spindle is an AI-driven operations analytics platform for car rental fleet operations, tracking real-time throughput, employee and vendor performance, reclean rates, and process bottlenecks across cleaning and vehicle turnaround workflows. It provides general managers and supervisors with per-employee productivity metrics, accountability logs, weather/airport disruption alerts, and plain-English querying to identify inefficiencies.</parameter> <parameter name="founders">[]

1 investor