AI & Machine Learning Startups

Sidepocket is a registered investment advisor that provides automated retirement investing and contribution planning tools for self-employed Americans, freelancers, and business owners with variable income. The platform calculates safe retirement contributions and uses tactical automated investing to help gig workers and independent professionals save for retirement throughout the year.

1 investor

Shipsidekick provides a logistics platform combining warehouse management, order management, transportation management, and ERP functions, with an AI assistant, for shippers and third-party logistics providers (3PLs).

1 investor

Sidekick develops digital therapeutics (DTx) programs for people with chronic conditions such as oncology, cardiovascular, metabolic, and inflammatory diseases, using gamification, behavioral psychology, and behavioral economics to improve health outcomes. Its Adaptive Care Paths combine multiple programs to support patients living with multiple chronic conditions.

1 investor

SideNote is a real-time workplace communication monitoring and coaching platform that uses AI to detect and prevent legal, compliance, and policy violations before messages are sent. The solution analyzes language in employee communications across email, chat, and documents, providing immediate guidance and aggregated insights to HR, compliance, and security teams.

1 investor

Sidian offers a software application that builds a unified data structure, or "company brain," around a company's data and connects to existing tools. It provides a structured, searchable memory so that institutional knowledge and precedent remain accessible to teams even after employees leave.

1 investor

Siemba offers a unified offensive security platform combining continuous attack surface mapping, autonomous vulnerability assessment, autonomous and expert-led penetration testing across web, API, cloud, network, mobile, and AI/LLM systems. It serves enterprise security teams with continuous, evidence-based testing, unlimited automated retesting, and certified engineer sign-off for audit-ready compliance.

1 investor

Sidekick is a lightweight clip that attaches to glasses and functions as a personalized smart assistant, enabling hands-free access to AI models, video capture, calls, translations, and reminders. It serves consumers who want to remain present and engaged without relying on their smartphones.

1 investor

Sievo provides spend analytics and carbon (CO2) management software for procurement teams, helping enterprises analyze spending data and calculate emissions in line with the Greenhouse Gas Protocol. The company serves global procurement organizations.

1 investor

Sift Lab provides analytics and personalization capabilities for ecommerce retailers and large retailers, using AI and segmentation to enable customer behavior prediction and omnichannel recommendations. The platform integrates with existing retail data infrastructure and marketing technology stacks while emphasizing low computational and storage costs.

1 investor

Sifted provides software that automatically audits carrier invoices, monitors carrier pricing changes, and models shipping contracts to reduce parcel shipping costs. It serves shippers and brands across industries such as consumer goods, manufacturing, and retail managing high-volume parcel operations.

1 investor

Sifty applies machine learning to automate repetitive data processing tasks for customs brokers in international trade, reducing manual workload and time spent on pattern recognition across thousands of data points.

1 investor

Siggy offers clinician-supervised, always-on AI therapy that combines daily check-ins, medication management, and goal tracking, with licensed psychiatrists reviewing and prescribing non-controlled psychiatric medications. The service serves individuals seeking mental health care and is available to U.S. residents, rolling out state by state.

1 investor

Sightec develops visual autonomy software for unmanned aerial vehicles (drones) that enables reliable navigation and situational awareness in GPS-denied, urban, and contested environments using computer vision technology. The company serves UAV operators and mission-critical applications across thousands of operational sorties.

1 investor

Sigma provides automation software for IT teams to orchestrate patching, remediation, and operational workflows across hybrid infrastructure without requiring scripts or DevOps expertise. The platform is designed for enterprise IT environments where uptime, auditability, and controlled change are critical requirements.

1 investor

Sigma Squared provides data-driven analysis for talent and hiring decisions, identifying performance and retention patterns specific to each organization. The platform integrates with existing HR systems to score candidates and internal promotions against organization-specific success profiles in real time.

1 investor

Sigma360 builds risk intelligence software that combines global data, entity resolution, and matching to deliver financial crime, credit risk, and decisioning solutions. It serves financial services, corporates, and professional services firms, supporting AML screening, monitoring, KYC, KYB, and CDD compliance.

1 investor

SigmaMind AI provides a Voice AI platform for developers and enterprise teams to build and deploy AI agents that can execute actions across voice, chat, and email channels. The platform is used for customer support automation, sales follow-up, appointment booking, and other enterprise communication tasks.

1 investor

A Chinese high-tech company providing industrial vision inspection systems and cloud-based computer vision services for manufacturing enterprises. The company delivers end-to-end vision solutions including optical imaging design, algorithm customization, and production data integration to help manufacturers improve efficiency, reduce costs, and enhance product quality across industries including medical aesthetics, medical devices, pharmaceuticals, and consumer electronics.

1 investor

Sigmatic offers a platform that consolidates scattered operational and financial data for provider-owned healthcare facilities, such as ambulatory surgery centers (ASCs), to give a real-time view of operations, costs, and margins. It identifies cost leakage, staffing needs, and savings opportunities to help these centers improve profitability.

1 investor

Signadot provides a Kubernetes-native developer platform that simplifies the development of cloud-native applications by enabling faster feedback loops and collaborative testing at scale. The platform targets development teams building complex microservices-based software.

1 investor

Signalcore offers an evaluation system that helps enterprises decide whether to build, buy, extend, or stop AI initiatives by mapping workflows, gathering vendor evidence, comparing options against internal requirements, and defining what a proof-of-concept must prove. It serves enterprise technology teams making AI adoption decisions.

1 investor

SignalFisher (formerly Bug Bounty Switzerland) runs continuous, expert-validated security testing programs that combine an AI-powered network of vetted security researchers with human oversight to give organizations an up-to-date view of their cyber risk. It serves CISOs and security leaders at enterprises in regulated industries such as banking, finance, insurance, government, healthcare, utilities, and critical infrastructure.

1 investor

SignalRank is an investment vehicle that uses an algorithmic selection process to identify top-decile, venture-backed Series B companies and provides pro-rata follow-on financing through a network of existing investors. It offers accredited and qualified investors single-investment exposure to a diversified portfolio, structured as a Maryland C Corporation with a targeted direct listing as a closed-end fund.

1 investor

SignalUp provides AI-powered full-service hardware product development, covering electrical and mechanical engineering, firmware, and manufacturing. It targets inventors and entrepreneurs who have hardware product ideas but little or no in-house engineering team.

1 investor