Advanced Manufacturing Startups

PhysicsX offers an AI and simulation software platform that combines physics inference with numerical simulation to help engineering and manufacturing enterprises design, optimize, and control products across the product lifecycle. It targets industrial engineers and technicians with tools such as simulation orchestration, Deep Physics Models, and no-code engineering applications.

9 investors

Prolific Machines licenses an optogenetics platform that adds light-based control to cell line development and GMP biomanufacturing, letting biopharma teams retrofit existing bioreactors and hosts to raise titers and manufacture complex molecule formats. It targets biopharmaceutical developers and manufacturers seeking higher productivity on difficult programs without re-platforming.

9 investors

Quantum Circuits develops superconducting quantum computers using dual-rail qubits with built-in error detection, designed to accelerate the path to fault-tolerant quantum computing. The company targets enterprises and institutions seeking reliable, scalable quantum computing solutions.

9 investors

Revoy builds electric vehicles or electric drivetrain technology. The company is hiring engineering roles focused on mechanical, electrical, and supply chain functions.

9 investors

RobCo provides modular, software-defined robotics with no-code workflow programming and digital simulation for configuring and validating industrial automation setups. It targets manufacturers of all sizes through a Robot-as-a-Service (RaaS) rental model, with offices in Munich and San Francisco.

9 investors

TO THE MARKET guides consumers to make purchasing decisions aligned with ethical and sustainable sourcing values, based on principles from its founder's best-selling book on conscious consumption.

9 investors

Tulip offers a no-code way to connect IIoT devices, sensors, smart tools, scales, cameras, and machines to its apps, letting manufacturers use device inputs and outputs to build triggers and workflows. It targets industrial and manufacturing operations that want to digitize processes and automate data collection.

9 investors

Ultra manufactures OP1, a stationary multi-purpose AI robot for warehouse automation that handles repetitive tasks like packing, sorting, and kitting. The robot targets industrial businesses and warehouses across the United States.

9 investors

Wandelbots develops Physical AI software for robotics that enables businesses to program and control robots without coding expertise. The platform serves manufacturing and industrial operators of all sizes seeking to scale automation.

9 investors

9 Mothers builds counter-drone defense systems that enable rapid deployment of point defense at infantry-mobile scale. The company serves military operators and procurement teams with hardware engineered for cost-effective attrition warfare against modern threats like FPV drones.

8 investors

Amplio builds infrastructure to help manufacturers unlock value from surplus inventory and manage circular manufacturing. The platform analyzes surplus stock, moves inventory, and clears warehouse space for enterprise clients while keeping assets in productive use.

8 investors

Ato Marine builds floating offshore platforms for high-performance computing and AI data centers, using standalone power generation and closed seawater cooling for location-agnostic deployment. The units are constructed in shipyards, towed to site, and moored together, with power supplied by adjacent vessels running on natural gas and, later, compact marine reactors.

8 investors

Atomic Alchemy builds privately-owned nuclear reactors dedicated to radioisotope production, including Molybdenum-99 used in most nuclear medicine procedures. It aims to supply radiopharmaceutical materials for diagnostic imaging, biological tracers, and cancer treatments.

8 investors

Baud Labs designs specialized AI chips that reduce the computational cost and power consumption of training and serving large language models by replacing multiplication-based arithmetic with addition-based operations. The company provides both custom silicon and a PyTorch-compatible compiler to enable organizations of all sizes to run AI workloads more efficiently.

8 investors

Bellwether Coffee makes an all-electric, ventless countertop coffee roaster along with a curated green coffee marketplace, roast profiles, and retail packaging for cafés and businesses to roast and sell coffee in-house. Its platform covers sourcing, menu and roast support, and retail program scaling for coffee shops.

8 investors

Carbon Crusher uses lignin-based materials to recycle existing road surfaces into carbon-negative replacements, removing approximately 1.5 tonnes of CO2 per 100 feet of road. The company offers crushing and refurbishment services to road owners and operators, with plans to use satellite monitoring for road condition assessment.

8 investors

CarbonChain provides software for companies and financial institutions to measure and account for greenhouse gas emissions across supply chains, from production to shipping to use of commodities and products.

8 investors

Cascade Space develops software tools and infrastructure for designing, building, testing, and operating spacecraft communication systems. The company serves aerospace and space companies seeking to accelerate development with reduced team requirements.

8 investors

Circe develops a biotechnology platform that uses advanced gas transformation to produce carbon-negative molecules at scale for manufacturing. The company serves industrial manufacturers seeking to decarbonize production of high-performance products while securing supply chains.

8 investors

ClearMotion develops active suspension systems for automotive vehicles. The company manufactures production-ready suspension technology with a focus on serving the automotive industry.

8 investors

CynLr builds a hardware and software machine-vision platform ("Object Intelligence") that lets robots see, grasp, and orient unknown objects without pre-training, and offers robotic systems such as CyRo, CyNoid, and Mantroid for manufacturing and logistics. Its technology targets factory assembly lines, autonomous driver assistance, and object-handling automation across varied product types.

8 investors

Destinus develops the Hornet Block 2, a mobile canister-launched dual-role system that intercepts subsonic aerial threats and conducts precision strikes against maritime and ground targets. It uses AI-coordinated swarm operations with EO/IR and radar guidance for autonomous engagement in GNSS-denied environments.

8 investors

Electric Hydrogen develops hydrogen production technology to support decarbonization. The company serves industrial customers seeking low-carbon molecular production.

8 investors

Electric Fish builds products for a decentralized electric grid system to enable energy independence. The company operates in the energy and critical infrastructure sector.

8 investors