Kyle Lefkoff
InvestorGeneral Partner at Boulder Ventures · Board director at Ambrosiabiosciences · Board director at Black Bear Energy · Board director at CommercialTribe
Colorado
Writes $1M – $5M checks
Find your path to Kyle
117 people in our graph can introduce you to Kyle.
Each arrow is one introduction. Sign up to fill in the first one.
Ask Peter Roshko to introduce you to Kyle
You →Peter · together at Trust Company of America (1999–2014) →Kyle
Ask Jamie Chen to introduce you to Kyle
You →Jamie · together at Ambrosiabiosciences →Kyle
Ask Sam Okafor to introduce you to Kyle
You →Sam · 5 people · together at Boulder Ventures →Kyle
Sign up to find every way you can get introduced to Kyle
- Your email: the people you already email who know Kyle
- 2nd- and 3rd-degree connections: people you know who worked, studied or invested with Kyle
- Your LinkedIn: the connections who can make the intro for you
We rank every route by how warm it is, so you raise on warm intros instead of cold emails.
About
Kyle Lefkoff applies nearly four decades of mountain-guide risk management to investing, co-founding and chairing Array BioPharma through FDA approval and its $11.8B Pfizer exit while prioritizing durable realized returns.
Contact· self-published, not guessed
Invests in
BiotechCloud ComputingData & InfrastructureEnergyEnterprise SoftwareMedical DevicesSaaS
Board director at Ambrosiabiosciences
Intro paths
In turn, Kyle can intro founders to Ambrosiabiosciences's investors below.
Ambrosiabiosciences's investors · 3
Board director at Black Bear Energy
Intro paths
In turn, Kyle can intro founders to Black Bear Energy's investors below.
Black Bear Energy's investors · 1
Co-founders at Black Bear Energy
Board director at CommercialTribe
Intro paths
In turn, Kyle can intro founders to CommercialTribe's investors below.
CommercialTribe's investors · 6
Co-founders at CommercialTribe

Experience
- Boulder VenturesGeneral Partnercurrent1995 — presentBoulder, Colorado
- Ambrosia Biosciences Inc.Chairman of the Board and Foundercurrent2024 — presentBoulder, Colorado, United States
- Black Bear Energy Inc.Board Member and Lead Venture Capital Investor2016 — 2024Boulder, Colorado
- AIARE- American Institute for Avalanche Research and EducationFounding Chairman of the Board2013 — 2023Boulder, Colorado
- InvitaeBoard Member and Lead Venture Capital Investor2018 — 2023Boulder, Colorado, United States
- Array BioPharmaChairman of the Board and Founder1998 — 2018Boulder, Colorado
- miRagen Therapeutics, Inc.Board Member and Founder2007 — 2017Boulder, Colorado
- Trust Company of AmericaMember of the Board of Directors1999 — 2014Centennial, Colorado
- American Mountain Guides AssociationLifetime Member, Board Member and Treasurer2001 — 2010Boulder, Colorado
- Colorado Venture ManagementGeneral Partner1986 — 1995Boulder, Colorado
Skills & more
+8 more
Corporate DevelopmentEquitiesFinanceInvestmentsMutual FundsIPOBusiness DevelopmentStrategic PlanningFrom Kyle's professional profile.
Deals · 5
ArcherDXBoard seat
via Boulder Ventures · filed Apr 2020 · $1.6M raise
miRagen TherapeuticsBoard seat
via Boulder Ventures · filed Feb 2017 · $40.7M raise
Black Bear EnergyBoard seat
via Boulder Ventures · filed Aug 2016 · $2.5M raise
Bioptix DiagnosticsBoard seat
via Boulder Ventures · filed Feb 2015 · $2.3M raise
CommercialTribeBoard seat
via Boulder Ventures · filed Feb 2015 · $4M raise
Attribution from SEC filings, press coverage, and firm rosters.
Other disclosed investments
Board seats
Array BioPharma
Investor
Ambrosia BiosciencesAtlantes Corp.Compatible Systems Corp.DharmaconGenomicaHauser Chemical ResearchLefthand NetworksLinerateLinerate SystemsMcDataMineralysNeXstar PharmaceuticalsWall Street on DemandWSOD
Sources: SEC Form D filings · the firm's website.
Colleagues at Boulder Ventures
Frequently asked questions
- Who is Kyle Lefkoff?
- Kyle Lefkoff applies nearly four decades of mountain-guide risk management to investing, co-founding and chairing Array BioPharma through FDA approval and its $11.8B Pfizer exit while prioritizing durable realized returns.
- Where does Kyle Lefkoff work?
- Kyle Lefkoff is General Partner at Boulder Ventures and Board director at Ambrosiabiosciences and Board director at Black Bear Energy and Board director at CommercialTribe.
- What does Kyle Lefkoff invest in?
- Kyle Lefkoff invests in Biotech, Cloud Computing, Data & Infrastructure, Energy, Enterprise Software, Medical Devices, SaaS.
- What check size does Kyle Lefkoff write?
- Kyle Lefkoff typically writes checks of $1M – $5M.
- What boards does Kyle Lefkoff sit on?
- Kyle Lefkoff holds tracked board seats at ArcherDX, Array BioPharma, Bioptix Diagnostics, Black Bear Energy, CommercialTribe, miRagen Therapeutics, miRagen Therapeutics.
- What companies has Kyle Lefkoff invested in?
- Investments tracked here include Ambrosia Biosciences, ArcherDX, Atlantes Corp., Black Bear Energy, Compatible Systems Corp., Dharmacon, Genomica, Hauser Chemical Research, Lefthand Networks, Linerate, Linerate Systems, McData, and 5 more.
- Where did Kyle Lefkoff go to school?
- Kyle Lefkoff studied at The University of Chicago Booth School of Business (Master of Business Administration (MBA), Finance); Vassar College (Bachelor of Arts (B.A.), Economics).
Founder mafias
The University of Chicago Booth School of Business mafia227
Also came through, then founded or led a company.
Vassar College mafia19
Also came through, then founded or led a company.
Invitae mafia13
Also came through, then founded or led a company.
Arraybiopharma mafia4
Also came through, then founded or led a company.
Boulder Ventures mafia4
Also came through, then founded or led a company.
Same school
Also attended The University of Chicago Booth School of Business1,037
+ 1,031 more
Also attended Vassar College64
+ 58 more
Shared employers
Also worked at Ambrosia Biosciences Inc.1
Also worked at Array BioPharma8
+ 2 more















































)










