TwentyTwo
YC S25New York City, US · Founded 2025 · 3 employees · 7 known investors
Twenty Two develops AI-powered biosecurity infrastructure for screening and monitoring biological threats across the emerging bioeconomy. The platform provides automated customer screening, functional sequence prediction, and model safeguards to help organizations comply with dual-use research regulations.
Also known as Mohi · Muon · Latch Biosecurity · Twenty Two
Founders & leadership· Y Combinator alumni (S25)
TwentyTwo was founded in 2025 by Evan Seeyave and Harmon Bhasin.
Investors · 7
Company profile
researched Aug 2026TwentyTwo is a New York City-based company that develops AI infrastructure for biosecurity, positioning itself as part of the "defensive stack" intended to prevent misuse of increasingly capable biological design tools. The company's stated premise is that AI is making biology easier to engineer, accelerating both therapeutic development and the ability of malicious actors to create pandemic-capable agents, so safeguards around biological AI models need to advance as quickly as model capabilities.
According to the acquirer's announcement, TwentyTwo builds "intelligence defense systems" that attempt to distinguish legitimate research (for example, studying pathogens such as SARS-CoV-2 or Ebola for pandemic preparedness) from work intended to cause harm, and then apply safeguards or grant capabilities accordingly. The company participated in Y Combinator's Summer 2025 batch and is categorized there under artificial intelligence, synthetic biology, biotech, compliance and security. Its Y Combinator profile also carries a launch post for Mohi, a debugging assistant for AI agents that instruments agent steps via an SDK and renders a visual graph of execution to identify where an agent failed; that launch describes founders who met at MIT, with prior experience in AI and distributed-systems observability at AWS and in automated testing at Google and AI evaluations at SecureBio.
Founding story
The Y Combinator profile's launch post states that the founders met at MIT and had previously worked together on multiple projects; it notes prior experience in AI and distributed systems observability at AWS and in automated testing at Google and AI evaluations at SecureBio [1].
Traction
Public sources report a team size of three and an "Active" status on Y Combinator's company directory; no customer, revenue or usage metrics are disclosed [1][2]. No jobs were posted on the YC platform for the company [2].
Latest developments
LatchBio's 29 June 2026 announcement of the acquisition stated that the TwentyTwo founders would lead Latch Biosecurity, that further announcements were expected in the following days, and that LatchBio was hiring biosecurity engineers [0].
▸Full profile — market position, technology, go-to-market, geography, history
Market position
TwentyTwo is an early-stage entrant in the biosecurity and AI-model-safeguards space; it was a Y Combinator Summer 2025 company with a three-person team before being acquired by LatchBio, a life-sciences software company, which established Latch Biosecurity around the team [0][1].
Technology
TwentyTwo describes AI infrastructure for biosecurity, including intelligence defense systems that classify whether a given biological request or research activity is legitimate or potentially malicious and then apply safeguards or grant capabilities accordingly [0][1].
Go-to-market
Sources indicate the work is aimed at organizations building and deploying biological AI models and at the life-sciences research community, where safeguards around such models are described as core infrastructure; the acquirer frames the customer problem as AI labs being unprepared for misuse risk [0].
Geography
Located in New York City, NY, United States [1][2].
History
The company was founded in 2025 and joined Y Combinator's Summer 2025 batch, operating from New York City with a team size of three and Tyler Bosmeny as its YC primary partner [1][2]. On 29 June 2026, LatchBio announced that it had acquired TwentyTwo; Harmon Bhasin, Evan Seeyave and John Wang joined LatchBio as Members of Technical Staff and now lead a unit called Latch Biosecurity [0].
Compiled by commissioned research from 6 cited public sources — announcements, filings, and press listed under research sources below.
Key figures
latest reportedCompany-reported or press-reported figures, each dated to when it was claimed — not independently audited.
Timeline · 3
launches, deals, and filingsLatchBio announced its acquisition of TwentyTwo, a Y Combinator Summer 2025 team building AI infrastructure for biosecurity. Harmon Bhasin, Evan Seeyave and John Wang joined LatchBio as Members of Technical Staff and lead the new Latch Biosecurity unit. Deal terms were not disclosed.
TwentyTwo was founded in 2025 and took part in Y Combinator's Summer 2025 batch, with Tyler Bosmeny as primary partner.
A company launch post on the Y Combinator profile introduces Mohi, a debugging assistant for AI agents that uses a lightweight SDK to tag agent steps (tool calls, memory access, context switches, decision logic), builds a visual graph of execution, identifies where the agent failed, and allows broken steps to be re-run with new inputs.
Dated company events from announcements, filings, and press; legal rows summarize public dockets and regulator releases.
In the news
▸Research sources · 6
primary sources listed
- LatchBio acquires TwentyTwo to form Latch Biosecurityblog.latch.bio · web
6 public sources were cited for this profile; the first-party ones are listed here.
Frequently asked questions
- What does TwentyTwo do?
- TwentyTwo builds AI infrastructure for biosecurity; acquired by LatchBio in June 2026 to form Latch Biosecurity.
- Who founded TwentyTwo?
- TwentyTwo was founded by Evan Seeyave, Harmon Bhasin in 2025.
- Who are TwentyTwo's investors?
- TwentyTwo's investors include Y Combinator, Andreessen Horowitz, avra, Bain Capital Ventures, HubSpot Ventures, MVP Ventures, Salesforce Ventures.
- Where is TwentyTwo headquartered?
- TwentyTwo is headquartered in New York City, US.