Mental Health Startups

Kyoto Text Lab develops sentiment analysis models based on natural language processing and psychology research, delivering them through consumer-facing AI applications intended to support communication and mental well-being. The company builds high-performance, purpose-specific sentiment models packaged into apps.

1 investor

Matsuli (株式会社祭) is a Japanese company operating "Itsudemo Okaeri," an SNS app for jotting down daily moments and anonymous, low-pressure social interaction based on psychological design principles. It also runs "Ebikatsu," an invitation-based open space combining an office and share house that hosts community events.

1 investor

Admirra develops a practice management system designed for mental health therapists and therapy group practices, helping them manage clients, scheduling, and administrative work without requiring technical expertise.

0 investors

Aiberry offers anonymous mental health screenings that guide people from self-reflection to insights and resources. The tool is designed to support early detection and engagement, reducing barriers such as stigma and uncertainty.

0 investors

American Treatment Network provides integrated addiction treatment combining behavioral healthcare, substance use disorder care, and physical health care to help patients recover from opioid and alcohol addiction. The provider uses a whole-person, evidence-based approach delivered by medical doctors, psychiatrists, therapists, and recovery support specialists in Pennsylvania.

0 investors

Ananda Scientific develops investigational CBD-based drugs delivered in soft gelatin capsules, with its Nantheia A1002N5S product formulated for rapid gastrointestinal absorption. The company is running FDA-approved clinical trials targeting PTSD, Social Anxiety Disorder, and radiculopathic pain, focusing on treatments for neuropsychiatric disorders.

0 investors

Arcade Therapeutics develops game-based digital therapeutics (DTx) that use attention bias modification to treat mental health conditions such as anxiety, depression, and addiction. The app-based treatments are aimed at patients and delivered through partnerships with health systems and insurers, and the company is pursuing FDA discussions and clinical trials.

0 investors

AZZLY provides AZZLY Rize, an all-in-one cloud-based platform combining electronic health records (EHR/EMR), practice management, and revenue cycle management for behavioral health and addiction treatment centers. The HIPAA-compliant SaaS serves clinical, medical, administrative, and billing staff at mental health and substance use disorder programs across various levels of care.

0 investors

Behave Health builds an all-in-one software platform for behavioral health providers, consolidating CRM (admissions), EHR (clinical documentation), RCM (billing), and ERP (operations) into one system. It serves addiction treatment centers, mental health clinics, sober living homes, and recovery residences across the United States, with HIPAA and 42 CFR Part 2 compliance.

0 investors

C3 Healthcare Rx provides medication management services including in-home prescription delivery for poly-chronic patients, with programs aimed at improving adherence and reducing medication errors and hospital readmissions. It also offers virtual behavioral health programs for non-acute mental health and addiction through the Collaborative Care model.

0 investors

CaredFor is a HIPAA-compliant patient engagement platform for addiction and mental health treatment programs, offering tools such as secure messaging, peer support communities, surveys, telehealth, appointment reminders, and relapse indicators. It helps treatment facilities improve patient outcomes, increase admissions conversions, and reduce attrition across levels of care including alumni and family programming.

0 investors

Charlie Health is a virtual provider of high-acuity behavioral healthcare, delivering personalized, evidence-based treatment programs that combine licensed clinicians, peer connection, and family involvement. It serves individuals and families in the U.S. facing serious mental health and substance use challenges, with a focus on young people.

0 investors

A mobile app aimed at helping reduce opioid use disorder, described in the context of telehealth and prescription management for patients and healthcare providers.

0 investors

Counslr provides live, text-based, non-clinical mental health support delivered by licensed professionals and available 24/7 through a mobile app. It sells organization-wide access to employers, schools, and community groups as a complement to traditional therapy and EAP programs.

0 investors

DemeRx develops psychedelic-based medications to treat addiction and mental health conditions. The company advances clinical trials for ibogaine and related compounds targeting alcohol use disorder and opioid addiction.

0 investors

Enveric Biosciences is a biotechnology company developing neuroplastogenic small-molecule drugs for neuropsychiatric and mental health disorders. It uses a proprietary discovery platform called The Psybrary to build an intellectual property portfolio of novel molecules targeting specific mental health indications.

0 investors

EpiVario is a biotechnology company developing small-molecule ACSS2 inhibitors that target a neuroepigenetic process involved in long-term memory formation, aimed at treating PTSD and substance use disorders. Spun out of the University of Pennsylvania's Epigenetics Institute, it develops pharmacotherapeutics for memory-related psychiatric and addiction disorders.

0 investors

Jaspr Health provides a digital assistant integrated into healthcare provider workflows to deliver evidence-based suicide risk assessments and create personalized safety plans for patients. It serves clinical staff and providers managing patients at risk of suicide.

0 investors

Farewelling helps people plan funerals and end-of-life arrangements, offering planning resources, articles, personal stories, and a podcast about death and dying. It also creates personalized tributes and bespoke farewelling plans.

0 investors

Flourish Labs was a healthcare startup that scaled mental health peer support through technology to address the youth mental health crisis, training young adults as certified Peer Support Specialists and Community Health Workers. It built Peers.net, a telehealth platform where teens and young adults could book one-on-one sessions with peer supporters; Peers.net is now part of WellSpace Health.

0 investors

Healing Springs Ranch is a residential treatment facility that provides comprehensive rehabilitation services for addiction, trauma, and mental health issues. The facility combines evidence-based therapies with structured programming and supportive care in a residential setting.

0 investors

Highland Springs Health is a behavioral health treatment facility that provides evidence-based inpatient care including cognitive behavioral therapy, dialectical behavior therapy, and trauma-informed treatment for individuals in mental health crisis or seeking long-term recovery.

0 investors

Hope River Ranch is an inpatient rehabilitation and recovery center that offers evidence-based treatment for substance use disorder, serving individuals and families affected by addiction. Its programs combine clinical treatment with nature, hobbies, and recreation, focusing on spiritual, physical, intellectual, and social wellness.

0 investors

Lyssn provides AI-powered tools for behavioral health and child welfare organizations to reduce staff burnout and improve implementation of evidence-based practices.

0 investors