Mental Health Startups

Onrise operates a national network providing athlete-specific mental health care, including peer support from retired professional athletes, licensed therapists, psychiatrists, sports dietitians, and 24/7 crisis coverage. It serves athletic organizations such as pro sports teams, athletic departments, elite youth programs, and college counseling centers, functioning as supplemental or standalone care embedded in existing athletic workflows.

1 investor

OOTify is a mental health support platform that uses AI and data-driven matching to connect individuals with personalized mental health services. It focuses on making mental health support more accessible to users in a digital environment.

1 investor

OpenSalud (openhealth) provides workplace health and wellbeing programs, including an employee assistance program, personalized health evaluations, and a healthy-living app with access to doctors, psychologists, nutritionists, and trainers. It serves companies and individual users, focusing on physical health, mental and emotional wellbeing, and healthy habits across Europe and Latin America.

1 investor

Optivio is developing a biofeedback-based SaaS platform, preparing for launch with its first customers. The company operates in the life science and digital health space.

1 investor

A practitioner-run practice offering intuitive energy healing, EFT tapping, guided imagery, and energy clearing sessions for individuals seeking emotional and spiritual clarity. Services are available online, by phone, or in person, and address emotional blocks, stress, and energetic imbalances.

1 investor

Owl Practice Suite provides an EHR and practice-management platform built for mental health therapists, covering telehealth sessions, client records and notes, scheduling, secure messaging, measurement-based care, and insurance claim filing. It also includes a therapist directory (Zencare), benefits verification, and billing tools to help private-practice therapists grow their caseloads and get paid.

1 investor

Peak Mind develops research-based stress and mental well-being products for high-performing adults, including VR/XR kiosk experiences, low-tech in-person products, and the Wellcapi AI API that gives personalized recommendations. It targets corporate, healthcare, and brain-performance settings, aiming to help users manage chronic stress and burnout.

1 investor

Perception Neuroscience is a clinical-stage biotech developing R-ketamine (PCN-101), a single-isomer glutamatergic modulator being studied as a rapid-acting antidepressant for patients with treatment-resistant depression. The company licenses intellectual property originally discovered at Chiba University and is running a Phase 2a proof-of-concept clinical trial.

1 investor

Peregrine Health partners with Federally Qualified Health Centers (FQHCs) to design, manage, and operate behavioral health service lines by placing licensed clinicians, handling program operations, and providing a technology platform for scheduling and outcome tracking. It serves community health centers addressing mental health and substance use care, offering programs such as Behavioral Health Integration and Medication-Assisted Treatment.

1 investor

Peregrine Health partners with Federally Qualified Health Centers (FQHCs) to design, manage, and operate behavioral health service lines, placing licensed clinicians and providing program managers and care navigators. It offers a technology platform for scheduling, outcome tracking, and analytics, and helps clinics build programs such as Behavioral Health Integration and Medication-Assisted Treatment.

1 investor

Perimeter Healthcare operates behavioral and mental health facilities offering residential, acute inpatient, dual diagnosis, and geriatric psychiatric programs for children, adolescents, and adults. It serves patients across 10 facilities, including specialized sensory-friendly care for neurodivergent youth ages 6–17, with locations in West Memphis, Missouri, and Springfield.

1 investor

Perspectives Health provides AI-powered clinical documentation and utilization review management for healthcare providers. The platform automates nightly chart audits, generates utilization review packets, manages documentation workflows, and tracks compliance issues for clinical teams.

1 investor

PlatoScience develops wireless, at-home transcranial direct current stimulation (tDCS) headsets and remote-management software for clinicians, researchers, and patients. Its products include PlatoCare, approved for treating depression in the EU and UK, and PlatoWork for general tDCS use in markets such as the US, Turkey, and Malaysia.

1 investor

PlaynVoice is an AI-powered documentation tool that transcribes patient therapy conversations in real-time and automatically generates clinical notes, progress reports, and official correspondence for mental health practitioners. The platform operates in German, English, French, and Swiss German, with data storage and processing in Switzerland.

1 investor

Pleso Therapy operates an online therapy platform that matches clients with vetted therapists for mental health support. Founded in Ukraine and expanded to Poland and Romania, it is now launching in the UK with locally accredited therapists.

1 investor

Plurawl is an AI-powered self-discovery coach that helps people overcome psychological barriers and limiting beliefs, targeting minority professionals. The platform combines digital health technology with clinical mental health support for personal and professional growth.

1 investor

Plus Capital is a venture capital and advisory firm that partners with high-profile artists, athletes, and cultural leaders to invest in emerging growth enterprise technology and consumer companies focused on health, wellness, future of work, and conscious consumer sectors.

1 investor

PointHealth uses AI, genomics, and data science to support personalized, precision care for healthcare providers, helping them understand patients through their biology, history, and experience. The company is starting in behavioral health, aiming to shorten recovery time and reduce relapses.

1 investor

Poppy Life Care offers integrative, person-centered wellness services—including wellness coaching, trauma-informed talk therapy, lifestyle and yoga coaching, nutrition counseling, and creative arts healing—for individuals with chronic pain, neurodivergence, developmental disabilities, and behavioral health needs. Its whole-person care model uses goal setting, mindfulness, breathwork, and movement to support emotional well-being, functional independence, and daily functioning.

1 investor

ProblemShared is an online mind health platform offering neurodevelopmental assessments for autism, ADHD and specific learning difficulties, plus talk therapy and post-diagnostic care for adults, children and young people. It is a CQC-regulated, practitioner-led service that partners with NHS trusts, universities, insurers and private healthcare providers in the UK.

1 investor

ProNovo Therapeutics is a biotechnology company developing precision small-molecule therapeutics for neuropsychiatric disorders, including Major Depressive Disorder and Schizophrenia. The company applies a precision-medicine approach based on genetic susceptibility, disease pathophysiology, and biomarkers to advance preclinical drug programs toward clinical development.

1 investor

Psmilin is developing a mobile app focused on mental health. The product has not yet launched and the page invites visitors to sign up for updates.

1 investor

PsycApps offers digital psychology-based solutions designed to build resilience and support professional growth. The platform serves learners and professionals seeking evidence-backed tools to overcome obstacles and develop key performance skills.

1 investor

Psych Congress runs in-person psychiatry conferences and educational events focused on practical psychopharmacology and clinical treatment strategies. It serves psychiatry clinicians, psychologists, and primary care providers, including residents, fellows, and early-career professionals, across US locations such as New York City and Miami.

1 investor