Mental Health Startups

Clymb develops emotional wellness programs for young people to build resilience, emotional intelligence, and reduce stress. The company targets schools and youth populations to prevent mental health and behavioral disorders.

3 investors

Cognito is a Canadian online mental health service offering cognitive behavioral therapy and psychiatric care for anxiety, depression, insomnia, and ADHD. The service operates virtually across British Columbia and Ontario, serving residents aged 17 and older.

3 investors

Conexa Saúde is a Brazilian digital health platform offering telemedicine, scheduled specialist appointments, digital urgent care, and mental health support via video consultation. It serves employers, health insurers, and healthcare professionals, providing corporate health benefits to employees across Brazil.

3 investors

Diamond Therapeutics is a preclinical biotechnology company developing drug treatments for psychiatric and neurological disorders, with a focus on the pharmacology and therapeutic use of psychedelic compounds. It brings together clinical researchers and pharmaceutical development experts to advance early-stage candidates for mood and related disorders.

3 investors

EmpowerU is a tech-enabled mental health support solution for schools and colleges, combining online skill-building lessons with daily 1:1 coaching by trained mental health experts to help students build resilience and improve wellbeing, attendance, and grades. It offers site-based licenses to schools as well as a credit-bearing course delivered through third-party online schools or directly, serving students across the United States.

3 investors

Enthea provides access to mental health treatment, including psychedelic-assisted therapy, positioned as a safe and affordable benefit for employers and healthcare consumers. The company serves corporate wellness programs, insurance plans, and health systems seeking to expand mental health treatment options.

3 investors

EuMentis Therapeutics develops therapies for neuropsychiatric disorders, targeting selective CNS circuits in the brain. Its lead product, EM-221, is a PDE10A inhibitor in development for schizophrenia and Parkinson's levodopa-induced dyskinesia, with a pipeline addressing conditions such as Alzheimer's-related agitation, treatment-resistant depression, bipolar disorder, and Tourette's.

3 investors

Eywa is a team of scientists and innovators focused on advancing mental health through research and partnerships.

3 investors

Feel collects physiological, clinical, and digital data from wearables, apps, and clinician dashboards, and uses proprietary algorithms to derive mental health markers such as mood, stress, sleep, and cognitive functioning. It integrates these measures into personalized digital therapeutic programs delivering real-time interventions for patients with various mental health conditions.

3 investors

Freespira develops an FDA-indicated medical device combined with clinical support for treating PTSD and panic disorder symptoms at home over 28 days. The solution serves health plans, healthcare providers, and self-insured employers seeking to improve patient outcomes and optimize healthcare resource utilization.

3 investors

GrayMatters Health develops Prism, an interventional psychiatry suite that uses fMRI-informed EEG digital biomarkers and self-neuromodulation to help patients regulate brain activity linked to conditions such as PTSD and depression. It is sold to psychiatry clinics to augment standard-of-care therapies.

3 investors

Headlight provides mental health services in the Western U.S., offering therapy and medication management delivered by licensed clinicians through a care coordination model that emphasizes personalized matching and integrated care.

3 investors

Headversity provides a workplace mental health platform offering proactive resilience and mental fitness training plus an implementation system that translates standards like ISO 45003 and the MHCC National Standard into actionable programs. It serves HR and people leaders at organizations, as well as sport teams and schools, to build psychologically safe cultures and measurable mental health outcomes.

3 investors

Hopscotch provides digital mental health tools for clinicians to deliver therapy services to children and families, addressing access barriers in pediatric mental healthcare.

3 investors

Huddle Up (formerly DotCom Therapy) provides integrated special education services for K-12 school districts, delivering speech, occupational therapy, school psychology, and mental health support through its own W-2 providers both virtually and in person. It also builds provider-facing technology to manage care delivery, compliance, and reporting, serving districts across the United States.

3 investors

Inner Peak provides 24/7 personalized mental wellness support for high school and college students through an AI-powered platform. The service combines human expertise with technology to deliver affordable, anonymous mental health resources.

3 investors

InStride provides virtual specialty care for young people ages 7 to 24 with anxiety, OCD, and related disorders, using evidence-based treatment enhanced by AI technology. The company works with insurance providers, referring physicians, and employers to make specialized mental health care more accessible and effective.

3 investors

Teladoc Health provides virtual care services connecting patients with providers for medical care, mental health, and chronic condition management. It serves health plans, employers, and hospitals in the U.S. with connected care technology and benefits solutions.

3 investors

Iris Telehealth provides telepsychiatry and behavioral health services to health systems, hospitals, and community clinics through a medical group of psychiatrists, LCSWs, and PMHNPs. The Joint Commission-accredited company supports partner organizations in delivering psychiatric care across all ages, acuity levels, and diagnoses in the United States.

3 investors

Kyan Health provides a workplace mental health platform offering a stepped-care model spanning self-care, coaching, therapy, work-life support, and crisis care, backed by a global network of licensed providers and Kai, a 24/7 AI companion. It serves employers with 500+ employees across industries, giving benefit managers engagement and wellbeing analytics tools to reduce absenteeism and burnout.

3 investors

Learn to Live offers online, evidence-based cognitive behavioral therapy (CBT) programs, live clinician coaching, crisis response, and mindfulness tools for common mental health issues such as anxiety, depression, and stress. It sells primarily to health plans, employers, and higher education institutions in the United States, providing members 24/7 digital access to self-guided mental health support.

3 investors

LifeStance provides mental healthcare services through a network of clinicians and therapists, delivering outpatient psychiatric and behavioral health treatment across the United States. The company serves patients seeking mental health support and works with providers and health systems to expand access to evidence-based care.

3 investors

Ivory develops cognitive health tools and resources for early detection and intervention of neurodegeneration. The company serves individuals concerned with brain health and cognitive performance through science-backed strategies.

3 investors

Lovewick is a free mobile app for couples that offers intimacy-building question cards, date ideas, and research-based relationship advice to help partners strengthen their connection. Positioned between dating apps and couples therapy, it personalizes content via a relationship quiz and adds features like anniversary countdowns and memory scrapbooking.

3 investors