Mental Health Startups

Eleanor Health is an outpatient addiction treatment program that delivers remote evidence-based care for substance use disorder, including medication-assisted treatment and counseling. The service addresses underlying trauma and behavioral health conditions alongside addiction through online consultations with addiction counselors and peer recovery specialists.

2 investors

Emote is an AI platform for schools that analyzes student emotional, social, and academic data to enable teachers, coaches, parents, and other stakeholders to identify and coordinate early interventions. It integrates data collection, real-time alerts, and collaborative tools to support whole-child development across diverse educational frameworks.

2 investors

Enrichly is a digital platform for pediatric behavioral health that combines gamified engagement with evidence-based interventions to strengthen self-esteem and emotional wellness in children and adolescents. It serves clinicians, therapists, counselors, parents, and schools with a closed-loop system that tracks progress and delivers data-driven insights.

2 investors

Enthea is a third-party administrator (TPA) that provides employer-sponsored mental health benefits covering psychedelic-assisted therapies, such as ketamine-assisted therapy, to address root causes of conditions like trauma, depression, and addiction. It offers benefit administration, claims processing, prior authorization, and a credentialed provider network for employers in the United States.

2 investors

EuMentis Therapeutics develops therapies for neuropsychiatric disorders, targeting selective CNS circuits in the brain. Its lead product, EM-221, is a PDE10A inhibitor in development for schizophrenia and Parkinson's levodopa-induced dyskinesia, with a pipeline addressing conditions such as Alzheimer's-related agitation, treatment-resistant depression, bipolar disorder, and Tourette's.

2 investors

Firefly Health provides virtual primary care through dedicated care teams that include primary care physicians, nurse practitioners, health guides, nurses, and behavioral health specialists. Care is delivered via video calls and chat through the Firefly Health app.

2 investors

First Tracks connects higher-acuity and treatment-resistant mental health patients with providers, devices, or treatment protocols suited to their needs. The company focuses on expediting access to advanced mental health care.

2 investors

Fluence provides education and professional certification in psychedelic therapy for therapists and mental health professionals, offering courses on molecule-specific treatments (MDMA, psilocybin, ketamine), harm reduction, and integration. It also supplies AI-supported clinical trial training for drug developers and lists certified practitioners in a therapist directory.

2 investors

GH Research is a clinical-stage pharmaceutical company developing mebufotenin (5-MeO-DMT) based therapies for psychiatric and neurological disorders. Its lead program, GH001, is a pulmonary inhalation formulation being developed for treatment-resistant depression, bipolar II disorder, and postpartum depression.

2 investors

GrayMatters Health develops Prism, an interventional psychiatry suite that uses fMRI-informed EEG digital biomarkers and self-neuromodulation to help patients regulate brain activity linked to conditions such as PTSD and depression. It is sold to psychiatry clinics to augment standard-of-care therapies.

2 investors

Greenspace Health provides a Measurement-Based Care platform for behavioral and mental health providers, integrating over 500 evidence-based assessments with automated data visualization and insights. Its software supports quality improvement and service innovation across levels of behavioral healthcare.

2 investors

Groov builds AI-powered platforms for healthcare systems and organizations to deliver personalized support in real time. Groov Health extends patient care between clinical appointments through structured journeys and AI support, while Groov Business provides organizational leadership with real-time visibility into workforce performance and delivers continuous coaching to employees.

2 investors

Heading Health is a mental health treatment center providing team-based, in-person care combining psychiatry, therapy, and nutritional support. The company serves individuals seeking mental health treatment at its physical centers.

2 investors

Headversity provides a workplace mental health platform offering proactive resilience and mental fitness training plus an implementation system that translates standards like ISO 45003 and the MHCC National Standard into actionable programs. It serves HR and people leaders at organizations, as well as sport teams and schools, to build psychologically safe cultures and measurable mental health outcomes.

2 investors

Healios provides online autism, ADHD and mental health assessment and support services for children, families, adults, employers and NHS partner organisations. It delivers clinically led, evidence-based care through a secure digital platform in the UK.

2 investors

Holivia provides an AI-powered mental health platform for enterprise employees, combining self-care content, personalized care pathways, and access to a network of psychologists. The platform serves mid-sized and large companies globally, addressing employee mental wellness through diagnostics, monitoring, and support services.

2 investors

Holmusk builds real-world data and analytics products for neuropsychiatry, including NeuroBlu Data (de-identified patient records mapped from U.S. electronic health records) and NeuroBlu Analytics, an evidence engine that lets researchers build patient cohorts and run observational studies. It serves researchers, clinicians, and payers in behavioral health, and also offers the MaST clinical decision support tool used in the U.K.

2 investors

Immersion offers SIX, a mobile app that identifies six key daily moments intended to support personal fulfillment and wellbeing.

2 investors

Inflow is an app-based program providing personalized coaching, strategies, and tools to help people with ADHD manage their condition. The platform combines clinical guidance from psychology experts with a supportive community, designed to make mental health support affordable and accessible for neurodiverse individuals.

2 investors

Innerwell is a telehealth mental health platform offering virtual psychiatry and therapy along with treatments like ketamine therapy, EMDR, and psychedelic integration. It coordinates care through a network of psychiatrists, therapists, and care advocates for patients seeking treatment for conditions such as depression and anxiety.

2 investors

Teladoc Health provides virtual care services connecting patients with providers for medical care, mental health, and chronic condition management. It serves health plans, employers, and hospitals in the U.S. with connected care technology and benefits solutions.

2 investors

Inwords is an AI-powered application that provides self-guided talk therapy and journaling for individuals seeking mental health support. The platform combines conversational AI with cognitive behavioral therapy principles to help users process emotions and build self-awareness.

2 investors

Learn to Live offers online, evidence-based cognitive behavioral therapy (CBT) programs, live clinician coaching, crisis response, and mindfulness tools for common mental health issues such as anxiety, depression, and stress. It sells primarily to health plans, employers, and higher education institutions in the United States, providing members 24/7 digital access to self-guided mental health support.

2 investors

Legion Health is a telehealth platform offering virtual psychiatric care and medication management for mental health conditions including ADHD, depression, anxiety, and bipolar disorder. The service connects patients with board-certified psychiatrists for diagnosis, psychiatric evaluations, and ongoing treatment.

2 investors