Medical Devices Startups

Seismi makes a wireless monitoring mat that tracks heart rate, respiratory rate, and activity in pets without restraints or wires. The product is designed for veterinary clinics and pet owners to monitor post-operative recovery, senior pet care, and multi-patient monitoring.

2 investors

Seismic Therapeutic is a clinical-stage biotechnology company that uses machine learning to discover and develop immunology therapies for autoimmune diseases. The company develops a pipeline of biologics derived from its IMPACT platform to control dysregulated adaptive immunity.

2 investors

Semarion is a University of Cambridge spin-out developing the SemaCyte platform, which converts adherent cells into barcoded, ready-to-use reagents for accelerated drug discovery and cell-based research. The platform combines materials engineering and cell biology to enable researchers to multiplex cell models and increase throughput in pharmaceutical assays.

2 investors

Sencure designs integrated biosensor chips for wearable health monitoring and medical devices, offering signal processing and electrophysiology expertise. The company serves device manufacturers building health monitoring and wellness applications.

2 investors

Sensome develops medical technology solutions at the intersection of engineering and life sciences, focusing on healthcare applications.

2 investors

Sensorum develops technology to reduce preventable hospitalizations among older adults by enabling proactive and preventative care management.

2 investors

Sensulin is a preclinical biopharmaceutical company developing glucose-responsive insulin therapies for type 1 and type 2 diabetes that aim to reduce hypoglycemia risk and daily injection requirements. The company's technology targets long-term complications of diabetes while potentially eliminating the need for separate basal and mealtime insulin dosing.

2 investors

Sensydia develops non-invasive wireless cardiac monitoring technology using machine learning to diagnose and manage heart disease. The system targets patients with heart failure and critical care issues, aiming to reduce readmissions and lower care costs.

2 investors

SentreHeart appears to now redirect to AtriCure, Inc., a medical device company. Its content references products such as the cryoXT probe for reducing residual limb pain related to amputation.

2 investors

Serif Biomedicines develops DNA-based therapies and nucleic acid delivery technologies for genetic medicine. The company aims to create tailored, long-acting treatments across multiple diseases.

2 investors

Shorla Oncology develops pharmaceutical products to address unmet needs in oncology. The company was founded by healthcare entrepreneurs with extensive experience in the pharmaceutical industry and regulatory affairs.

2 investors

GC Showa Yakuhin is a dental care company specializing in oral healthcare products and solutions. The company focuses on supporting patients and caregivers in an aging society by emphasizing the connection between oral health and overall wellness.

2 investors

Signant Health provides software platforms and clinical trial solutions for life sciences companies to manage patient-reported outcomes, evidence generation, and digital endpoints in drug development programs across multiple therapeutic areas.

2 investors

Signatur Biosciences develops molecular diagnostic solutions using qPCR technology for in vitro diagnostics, targeting clinical and laboratory markets. The company aims to deliver advanced diagnostics on widely available instrumentation to expand access to cutting-edge healthcare globally.

2 investors

SimBioSys builds AI-powered 3D visualization and diagnostic technology that models tumors as "digital twins" to support individualized cancer treatment planning. Its tools serve breast cancer surgeons and clinicians for preoperative planning and analysis in oncology.

2 investors

Baxter provides medical devices, connected care solutions and injectable technologies used across hospitals, physician offices, alternate care sites and home care. Its portfolio spans care communications, infusion and nutrition, diagnostics, pharmaceuticals and surgical technologies for clinicians and patients.

2 investors

Singular Medical develops implantable cardiac devices and digital health solutions for arrhythmia and heart failure management, including pacemakers, defibrillators, and remote monitoring systems. The company serves hospitals and patients in China and developing markets with products spanning screening, diagnosis, treatment, and monitoring across implant and AI domains.

2 investors

Sionna Therapeutics is a biopharmaceutical company founded in 2019 that develops small-molecule therapies for cystic fibrosis by targeting and stabilizing NBD1, the domain of the CFTR protein where the common ΔF508 mutation occurs. It is advancing a portfolio of NBD1 stabilizers and complementary CFTR modulators intended to be used in combination to normalize CFTR function in CF patients.

2 investors

Sirius NeoSight develops a patented technology that measures cell membrane fluidity using a fluorescent molecule to detect, isolate and characterise Circulating Tumour Cells (CTCs) from blood samples. Aimed at oncologists, the technology supports early cancer detection, monitoring of recurrence and treatment resistance, and personalised therapy selection for metastatic and aggressive cancers.

2 investors

Sirius Therapeutics is a biopharmaceutical company developing siRNA-based therapeutics, including work in the anti-coagulant therapeutic area. It focuses on drug discovery and clinical development of RNA-based medicines.

2 investors

Sixfold develops RNA delivery technology for the biotech industry. The company was founded by an oncologist and plant scientist and focuses on advancing RNA-based therapeutic approaches through proprietary delivery methods.

2 investors

Skin Analytics develops DERM, an autonomous AI as a Medical Device for skin cancer assessment, aimed at giving patients dermatologist-quality evaluations and lowering the cost of skin cancer care for health systems. It serves health systems and insurers, operating in the AI-driven medical device and digital health space.

2 investors

Skribe develops a wearable cardio-oncology platform with a battery-free adhesive patch that assesses cardiac function, starting with LVEF, in minutes at the clinic or at home. It serves oncologists screening cancer patients for cardiotoxicity and can support cardiac safety monitoring in oncology clinical trials.

2 investors

Skylabs makes CART BP, a ring-shaped blood pressure monitor worn on the finger that automatically measures systolic/diastolic blood pressure and pulse using PPG (photoplethysmography), including during sleep. It is a certified medical device aimed at people managing hypertension at home, with data synced to a companion app for daily, weekly, and monthly tracking.

2 investors