Medical Devices Startups
5,183 companies tagged Medical Devices, with their investors and founders.
OCON Therapeutics develops intrauterine drug-delivery products based on its IUB platform, including a hormone-free IUD contraceptive, an endometrial ablation device for abnormal and heavy menstrual bleeding, and a therapeutic-delivery device targeting conditions such as endometriosis and myomas. The company focuses on women's health, delivering treatments directly through the uterus to avoid systemic side effects.
3 investors
Octave develops blood-based biomarker tests for neurodegenerative diseases including multiple sclerosis, Parkinson's disease, and Alzheimer's disease. The company's tests enable physicians and patients to measure disease progression and treatment response through blood draws rather than traditional clinical assessments.
3 investors
Oculis is a biopharmaceutical company developing pharmaceutical drug products, with a focus on ophthalmic and eye disease treatments. It conducts formulation, process, and analytical development to advance drug candidates from early research through later development stages.
3 investors
Oculogica develops FDA-cleared concussion assessment devices that use proprietary eye-tracking technology to measure abnormal eye movements caused by traumatic brain injury. Its tools serve clinicians and athletic trainers across settings including sports sidelines, pediatric and urgent care clinics, accident/personal injury clinics, and military care.
3 investors
OKKO Health develops smartphone and tablet apps that measure vision through games built on vision science, for use in clinical practice, scientific research, and drug and device R&D. The company captures home-monitoring data to build predictive algorithms that identify sight problems early and flag who needs professional eye care.
3 investors
OncoPrecision develops precision oncology medicines, including antibody-drug conjugates and bispecific antibodies, for blood cancers and hard-to-treat solid tumors. The company uses patient-derived tumor biology and AI-enhanced discovery to identify therapeutic targets and engineering approaches.
3 investors
Onera Health provides clinical-grade remote diagnostics and monitoring solutions for healthcare professionals, with an initial focus on sleep health. The company operates globally and aims to make remote health monitoring accessible and user-friendly.
3 investors
A pharmaceutical company developing therapeutics across oncology, hematology, neuroscience, immunology, and cardiovascular disease with a pipeline of 50 compounds targeting 40+ disease areas.
3 investors
OrganoidSciences develops organoid-based regenerative therapeutics and evaluation solutions, operating dedicated GMP manufacturing facilities for cell/organoid drug production. Its lead program ATORM-C is an organoid therapy for inflammatory bowel disease, with clinical development across Korea, the US, and Europe.
3 investors
Orna Therapeutics develops RNA and lipid nanoparticle (LNP) based therapies for treating diseases including oncology and cell therapy applications. The company leverages proprietary drug development expertise in oRNA and LNP technology platforms.
3 investors
OrthAlign develops medical device technology for precise alignment during hip and knee replacement surgery, serving orthopedic surgeons in the surgical technology space.
3 investors
OSSIO develops OSSIOfiber, a bio-integrative bone fixation implant material made from natural mineral fibers that provides stability during healing and integrates fully into bone over 18-24 months, avoiding permanent metal hardware. The implants are used in orthopedic surgical procedures such as hammertoe and other bone-healing treatments.
3 investors
OSSTEC is a medical device startup developing a 3D-printed biomimetic knee implant intended for use in hospitals. Founded out of Imperial College London, the company focuses on orthopedic implants aimed at improving patient mobility and quality of life.
3 investors
OxiWear makes an FDA-cleared ear-wearable device that continuously measures blood oxygen and pulse rate in real time, with accuracy across skin tones, and sends text, app, and vibration alerts when oxygen drops below set thresholds. The health data can be shared with clinicians, serving patients such as those with pulmonary conditions and their caregivers.
3 investors
PanTher develops targeted cancer therapeutics that deliver drugs directly to tumor sites at high concentrations over extended periods, aiming to improve clinical outcomes while reducing side effects. The platform is designed to be applicable across multiple therapeutic types for oncology treatment.
3 investors
Paradigm Health operates a platform that increases patient access to clinical trials through a provider-facing infrastructure combined with AI-powered research technology. The company serves patients, healthcare providers, researchers, and study sponsors in the clinical research and life sciences industry.
3 investors
Custom Health operates a connected infrastructure combining pharmacy services, in-home monitoring technology, and pharmacist-led clinical care to support medication management at home. The company serves patients, caregivers, healthcare providers, and health plans.
3 investors
PathogenDx provides molecular pathogen detection assays using proprietary D3 Technology for rapid, multiplexed identification of bacterial, fungal, and viral pathogens in food, agricultural, clinical, and environmental samples.
3 investors
Pathware provides real-time biopsy quality assessment technology for pathologists to determine sample adequacy on-site, reducing repeat procedures and unnecessary surgeries. The company serves pathology practices and healthcare systems performing diagnostic biopsies.
3 investors
Provider of the SmartHospital Platform, a connected system that links patient rooms, operating suites, and other hospital facilities to support clinical workflows. Serves healthcare facilities seeking to coordinate care delivery and manage resources.
3 investors
Pearl Diagnostics develops diagnostic assays for detecting fungal infections, including a urine-based test for Aspergillus. The company operates in the medical diagnostics and biotech industry.
3 investors
Peloton Therapeutics is a clinical-stage pharmaceutical company developing first-in-class small molecule medicines targeting HIF-2Ξ± for cancer and other life-threatening conditions, with initial focus on kidney cancer and VHL disease.
3 investors
PentaBind designs programmable aptamersβsmall RNA/DNA molecules with sub-nanomolar binding affinityβfor continuous sensing and diagnostics applications (e.g., monitoring hormones and biomarkers) and targeted therapeutics in oncology and drug delivery. The platform reduces aptamer design cycles from months to ~22 days and delivers application-ready assets rather than just binders.
3 investors
Petal is developing an incisionless surgery platform using Millisecond Pulse Histotripsy, a form of focused therapeutic ultrasound that breaks down targeted diseased tissue without incisions, heat, or trauma. The system is designed for patients, clinicians, and hospitals as an alternative to conventional and robotic surgery.
3 investors