Medical Devices Startups

Suture Ease develops and commercializes proprietary devices for laparoscopic surgery, with a flagship CrossBow Fascial Closure System that uses a "snare guide" technology and suture passer for trocar site closure. It is a medical device company serving the minimally invasive surgery market.

1 investor

Suturion develops SutureTOOL, a medical device that enables surgeons to perform standardized abdominal wall fascia closure using the small-bites technique to improve patient outcomes and reduce complications. The company serves surgeons and hospitals globally with a focus on safety, efficiency, and cost-effectiveness in surgical care.

1 investor

Svastia is a clinical-genomic platform that uses genetic screening to improve cancer therapy outcomes for pharmaceutical companies and hospitals. The platform bundles contract research services with bioinformatics analysis, and coordinates a distributed network of laboratory service providers to support drug development, clinical trial patient selection, and personalized treatment recommendations.

1 investor

SweetSpot provides a remote diabetes monitoring and management platform that improves data accessibility for clinicians and supports patients using diabetes technology such as CGMs and insulin pumps. It serves diabetes care providers and patients in the digital health space.

1 investor

Swift Sync develops a patented temporary A-V sequential pacing catheter that self-positions in the right-side heart chambers to maintain endocardium contact for synchronous dual-chamber pacing, potentially without fluoroscopic guidance. It is intended for use in operating rooms, cath labs, and critical care settings for procedures such as open heart surgery, TAVR, ablations, and conditions like bradycardia and heart block.

1 investor

Swiftsure Innovations develops medical devices for oral care, including the SwishKit, aimed at improving oral care for mechanically ventilated patients. Its products are designed for nurses and clinicians in critical care settings.

1 investor

Swiss Decode develops portable DNA detection devices that deliver results in under an hour, enabling evidence collection at the point of need without external laboratory testing.

1 investor

Swixx BioPharma is a specialized pharmaceutical distributor and market access partner that represents international biopharma, OTC, and medical device companies in markets across Central & Eastern Europe, the Middle East, North Africa, Latin America, and Eurasia. The company operates as an indirect route-to-market solution for healthcare companies seeking regional expansion without establishing their own subsidiaries.

1 investor

Sycai Technologies develops AI software for automated detection and follow-up monitoring of abdominal lesions in medical imaging to support early cancer diagnosis. The platform integrates into hospital radiology systems to assist radiologists in standardizing diagnostic workflows and reducing diagnostic errors.

1 investor

Syenex provides cell delivery technologies and contract development services for therapeutic cell engineering, serving biopharmaceutical companies developing cell-based therapies. The company integrates cell engineering and delivery capabilities with regulatory support for clinical development.

1 investor

Symphony Robotics develops investigational robotic technology for healthcare applications. The company is currently in development and undergoing regulatory review with the FDA.

1 investor

SymPhysis Medical develops medical devices to treat malignant pleural effusion, a complication affecting late-stage cancer patients. The company's technology, releaze™, is a drainage device designed to improve patient independence and quality of life.

1 investor

Symplast provides practice management and business intelligence software designed specifically for aesthetic medicine and plastic surgery practices. The platform combines administrative tools, patient engagement features, and practice analytics to help aesthetic physicians reduce operational burden and focus on patient care.

1 investor

Synapse Biomedical develops and commercializes neurostimulation medical devices, including the NeuRx Diaphragm Pacing System (DPS), which uses electrical stimulation of the diaphragm to treat chronic respiratory insufficiency in patients with spinal cord injuries and ALS. The company serves clinicians and patients dependent on mechanical ventilation.

1 investor

Synaptic Bionics develops non-invasive neuromuscular sensing and adaptive AI technology to decode human intention and enable control of prosthetics, rehabilitation systems, and robotics. The company targets individuals with mobility impairments and muscular or peripheral nerve damage seeking to restore mobility and independence.

1 investor

Synaptic works on a platform focused on improving arrhythmia and related cardiac disease outcomes. The company frames its work around supporting patient outcomes in a holistic manner.

1 investor

Synaptrix develops NOVABLOC, a non-opioid neuromodulation therapy that uses electrical stimulation to provide targeted, long-lasting postoperative pain relief. The device is being evaluated in a US randomized controlled trial for perioperative pain management, aiming to reduce opioid use after surgeries such as knee replacement.

1 investor

SynCardia manufactures the world's first commercially approved total artificial heart for patients with end-stage heart failure awaiting transplant. The company develops and delivers mechanical circulatory support devices as alternatives to heart transplantation for critically ill patients.

1 investor

SynchNeuro develops a non-invasive, behind-the-ear wearable sensor that analyzes brain signals (EEG) to continuously monitor glucose levels, sleep quality, and other metabolic metrics. Aimed at individuals managing metabolic health, especially those with prediabetes, it uses machine-learning models as a pain-free alternative to traditional glucose monitoring.

1 investor

KEWS300 is a hospital ward management system that displays real-time patient vital signs, staff assignments, and early-warning scores on a central station screen to help nurse managers optimize ward operations and patient care. The platform enables quick monitoring of nurse workloads and patient acuity across all admitted patients.

1 investor

SynDaver designs and manufactures synthetic humans and anatomical simulators made from water, salts, and fibers that replicate living tissue including muscles, bones, organs, and vessels. Its products serve medical device manufacturers, hospitals, medical and educational institutions, government and military bodies, and industrial customers for uses such as surgical training, medical device testing, education, and product/armor testing.

1 investor

Syndex develops mcPCR (methyl copying PCR), a proprietary platform technology that amplifies DNA while preserving methylation patterns, addressing the challenge of low DNA levels in clinical samples. The technology targets clinical applications including oncology and early cancer detection, residual disease and treatment monitoring, drug development, and chronic disease detection.

1 investor

Synergia Medical develops optoelectronic implantable medical devices, including its NAO.VNS vagus nerve stimulation system, which is undergoing First-In-Human clinical evaluation through the AURORA study. The company is based in Belgium.

1 investor

Synergy provides in-home video electroencephalogram (EEG) testing services for neurological diagnosis, delivering hospital-grade accuracy to patients' homes. The company serves physicians and healthcare organizations seeking diagnostic neurocare services.

1 investor