Medical Devices Startups

Sensible Medical develops the ReDS system, a non-invasive monitoring technology that measures lung fluid levels in real-time to help clinicians manage heart failure and fluid-related conditions. The company serves healthcare providers and patients to reduce hospital readmissions and improve disease management.

1 investor

Sensimed SA develops the SENSIMED Triggerfish, a non-invasive soft contact lens-based device that automatically records continuous ocular dimensional changes over 24 hours to support glaucoma management. The company centralizes and analyzes this data on a registry to help ophthalmologists differentiate indications, personalize treatment, and assess treatment efficacy.

1 investor

Sensocure develops implantable microsensor technology to monitor tissue oxygen levels and detect ischemic events before irreversible damage occurs. The Norwegian medical device company targets clinical applications in tissue monitoring and prevention of ischemic injury.

1 investor

Sensoreal develops portable diagnostic tools for detecting marine biotoxins in shellfish, enabling real-time on-site testing to protect public health and support the seafood industry. The company serves shellfish harvesters, processors, and regulatory laboratories with rapid lateral flow assays for detecting paralytic, amnesic, and diarrhetic shellfish poisoning toxins.

1 investor

SensTek Diagnostics develops a solid-state molecular testing platform that enables rapid bacterial, fungal, and viral diagnostics across clinical, agricultural, water, and food safety applications. The company targets improved access to accurate diagnostics for communities underserved by traditional laboratory infrastructure.

1 investor

SentiAR builds CommandEP, an FDA-cleared mixed-reality holographic augmented reality platform for cardiac electrophysiology that converts real-time catheter data into hands-free 3D holograms and virtual screens for electrophysiologists during procedures. Sold to hospitals and ambulatory surgery centers, it aims to replace boom-mounted display systems and improve navigation accuracy in the EP lab.</parameter> <parameter name="hq_city">St. Louis

1 investor

A biopharmaceutical company developing novel medicines for rare diseases, serving patients and caregivers from early detection through therapeutic intervention.

1 investor

Seonix develops a genetic risk score to identify individuals at elevated risk of glaucoma, serving eye health professionals, patients, and researchers. The company uses large-scale genetic datasets and advanced techniques for clinical risk prediction to help prevent vision loss.

1 investor

A company developing wearable devices combined with artificial intelligence to detect early signs of sepsis in patients outside hospital settings.

1 investor

Septest develops rapid point-of-need diagnostic tests for detecting infections and inflammation, including its multi-marker TRISEP test aimed at pre-hospital and community triage. The tools are intended for frontline healthcare professionals to speed sepsis detection and reduce antimicrobial resistance, with a focus on accessibility including in low- and middle-income countries.

1 investor

Sequel Med Tech develops wearable insulin delivery devices and precise drug delivery technology for people with diabetes and others, building on the legacy of the insulin pump. The company serves people with type 1 diabetes and healthcare providers, with plans to support drug delivery beyond diabetes.

1 investor

Sequence develops 3D-printed mesh-silicone orthotic insoles combined with objective movement analysis of the kinetic chain (feet through spine), using standing foot scans and dynamic gait data to provide targeted sensory support that helps improve everyday movement. The product is aimed at orthopedic and biomechanical applications, delivered through partner locations.

1 investor

Sequoia Vaccines develops vaccine treatments for infectious diseases, with a focus on prevention of recurrent urinary tract infections. The company operates in the biotechnology industry with expertise in vaccine development, clinical trials, and manufacturing.

1 investor

Serán is a contract development and manufacturing organization (CDMO) that provides drug formulation, development, and manufacturing services to pharmaceutical companies. The company specializes in process engineering, scaleup, and commercial manufacturing of solid dosage forms and advanced pharmaceutical technologies.

1 investor

SERB is a pharmaceutical company specializing in rare diseases and emergency medicine, with a portfolio of 70+ medicines including antidotes for chemical, biological, radiological and nuclear threats. The company serves hospitals, healthcare systems, first responders, and patients with rare conditions in oncology, neurology, and metabolic disorders across 100+ countries.

1 investor

SERDA therapeutics is developing a prescription enzyme-based product for therapeutic debridement, using a proteolytic enzyme to selectively digest and remove necrotic tissue and eschar from wounds. It targets burn injuries and chronic wounds such as open leg and diabetic foot ulcers.

1 investor

Serpar is an investment firm partnering with medtech and healthcare companies across Northern Europe, with portfolio holdings in medical device distribution, diagnostics, and assisted living products.

1 investor

Seroxo is a biotech company developing technology in the areas of immunology, cancer, and infectious disease, supported by a clinical advisory board of specialists. The company is associated with the University of Oxford research community.

1 investor

Serviam partners with senior living operators to provide integrated diagnostics, pharmacy, and hospice services designed to improve care quality and create new revenue streams for long-term care communities. The company operates as an equity partnership model, managing day-to-day operations of specialty services to reduce burden on senior living operators.

1 investor

SetBone Medical develops solutions for spinal care and orthopedic applications. The company is advised by leading spine surgeons and orthopedic specialists.

1 investor

ShanX Medtech develops a diagnostic platform that identifies bacterial infections and determines antibiotic susceptibility from patient samples within approximately one hour. The system serves clinicians in hospital microbiology labs and point-of-care settings, providing targeted treatment guidance based on individual patient needs.

1 investor

Shield Bio develops nanopore sequencing technology for clinical use, designed to run rapid genetic tests in healthcare settings. The company initially targets infectious disease diagnosis and sepsis detection to reduce treatment delays.

1 investor

Shifamed develops and brings to market medical devices designed to address unmet clinical needs in healthcare. The company accelerates medical technology innovation through collaboration between experts from within and outside the medtech industry.

1 investor

SHOEBOX is a tablet-based audiometry platform that conducts hearing assessments on mobile devices; it has been clinically validated across multiple studies for use in various settings including clinics, schools, and remote locations.

1 investor