Medical Devices Startups

Palvella Therapeutics develops QTORIN™, a targeted topical formulation of rapamycin designed to treat rare skin diseases including microcystic lymphatic malformations and cutaneous venous malformations by delivering the active ingredient to the dermal layers with minimal systemic absorption.

1 investor

Panacea Medical Technologies manufactures radiation medical devices with extended product support and end-of-life management programs. The company emphasizes circular economy principles by designing products with 95% recyclable materials and coordinating responsible disposal of electronic, radioactive, and metal waste through authorized channels.

1 investor

Panda Surgical develops handheld robotic platforms with AI-powered software to enhance neurosurgeons' dexterity and control during minimally invasive brain and spine procedures. The system aims to expand access to complex neurosurgical techniques beyond specialized centers by enabling surgeons to perform delicate maneuvers safely in confined spaces.

1 investor

Pandhora is an innovative Italian SME that designs, manufactures, and distributes high-quality wheelchairs and related mobility devices, including the PEVO lightweight compact wheelchair and the EP3 electric propulsion unit. It also participates in biomedical and engineering research projects, drawing on a team of mechanical and biomedical engineers.

1 investor

Pangea Biomed develops computational and data-driven platforms to advance precision oncology, helping researchers and clinicians select optimal cancer treatments and understand tumor biology. The company serves drug development teams, oncologists, and cancer centers globally.

1 investor

Pangolin Therapeutics develops Pangomers, synthetic molecules designed to target and interfere with intrinsically disordered proteins involved in Type 2 Diabetes, neurodegeneration, and cancer. The company uses molecular modeling and drug discovery tools to create therapeutics for previously undruggable protein targets.

1 investor

Pano Therapeutics develops small-molecule drug candidates targeting mitochondrial dysfunction, with a lead program in Fragile X Syndrome and neurodevelopmental disorders. The company's approach builds on metformin's mechanisms and is designed to serve patients with syndromic neurodevelopmental disorders.

1 investor

Panoptive provides a software platform that continuously monitors clinical trials by converting monitoring reports and electronic data capture (EDC) data into structured findings, documented decisions, and audit-ready oversight records. The platform serves sponsors and clinical operations teams conducting regulated trials and helps organizations surface quality issues early while maintaining inspection-ready documentation.

1 investor

Panthura develops non-viral DNA delivery technology for sustained therapeutic effects in specific tissues, with potential for repeated administration. The company is advancing its platform through preclinical and clinical development stages.

1 investor

Papcup develops a non-invasive cervical screening platform using electrochemical biosensing technology to provide faster, more accessible diagnostics. The company targets women seeking cervical cancer screening and aims to expand its biosensor-based approach across broader healthcare diagnostics.

1 investor

Paper Plane Therapeutics develops virtual reality therapies to manage pain and anxiety in patients during medical procedures. The company licenses immersive VR solutions to hospitals, clinics, and care facilities.

1 investor

Parable develops software tools for wound care professionals that integrate modern data management and collaboration capabilities to improve clinical outcomes and reduce treatment costs.

1 investor

Paradigm Therapeutics is a biopharmaceutical company developing Zorblesia (SD-101), a proprietary topical whole-body therapy for treating the wounds, lesions, and infections associated with all subtypes of Epidermolysis Bullosa (EB), a rare genetic connective tissue disorder. The company focuses on discovering and delivering therapies for patients with serious, life-threatening diseases.

1 investor

Paragon 28 manufactures the PRECISION MIS Bunion System, a minimally invasive surgical instrument set for correcting bunion deformities through metatarsal osteotomy and fixation. The system is designed for orthopedic surgeons and hospitals performing bunion correction procedures.

1 investor

Paragonix Technologies develops, manufactures, and services organ preservation devices that combine cooling techniques with digital tracking and monitoring for clinicians managing donor organs during transplantation. It also maintains the GUARDIAN clinical registries, a database of organ preservation and post-transplant outcome data, serving the organ transplant industry.

1 investor

Parasight develops in-clinic diagnostic laboratory systems for veterinary practices, enabling rapid automated analysis of fecal, blood, and urine samples with digital results in under six minutes. The systems support both companion and large animal practices through sample preparation, imaging, and measurement capabilities integrated with veterinary practice management software.

1 investor

Participant designs and manufactures affordable, ISO-certified mobility products including wheelchairs and walking aids for children and adults with disabilities. The company operates a global distributor network to serve underserved populations in over 40 countries, combining commercial scaling with a social mission focused on accessibility for economically marginalized communities.

1 investor

Pathfinder Solutions Group is a consulting firm that provides advisory services to venture-backed portfolio companies of Stony Lonesome Group, with offerings across medical, healthcare, cybersecurity, data, and grant funding areas.

1 investor

Pathios Therapeutics is a drug discovery and development company working on small-molecule drugs that block the immune cell receptor GPR65, which senses the acidic tumor microenvironment, with a lead asset (PTT-4256) aimed at treating solid cancers. The company targets cancer immunotherapy applications across a broad range of solid tumors.

1 investor

Pathnostics is a CAP-accredited and CLIA-certified diagnostics laboratory offering histopathology, cytology, and molecular tests across urology, women's health, and gastroenterology. Its flagship platform, Guidance UTI, combines molecular detection with proprietary Pooled Antibiotic Susceptibility Testing (P-AST) for infectious disease and cancer diagnostics.

1 investor

Pathobin sells microscope imaging accessories, including C-mount phototube adapters for Olympus microscopes, USB C-mount cameras with real-time image stitching, and universal smartphone microscope adapters. The products are marketed for education and research use.

1 investor

iDose TR is a treatment for open-angle glaucoma and high eye pressure. The page serves as a patient story collection portal for individuals undergoing treatment.

1 investor

PBD Biotech develops phage-based diagnostics, applying its technology to disease detection across clinical and veterinary applications. The company works in the diagnostics industry with expertise spanning disease management and policy.

1 investor

PBS Biotech develops Vertical-Wheel bioreactors and related accessories for scalable manufacturing of cell therapies, including allogeneic therapies derived from induced pluripotent stem cells, mesenchymal stem cells, and CAR-T or NK cells. It serves cell therapy developers from R&D through clinical trials and commercialization, offering products, consulting packages, and process scale-up support.

1 investor