Medical Devices Startups

Liveo Research produces specialty materials for primary packaging in the pharmaceutical and medical device industries, as well as shrink sleeve labels, serving customers globally with innovative solutions. The company also provides value-added packaging consultation services to help customers identify sustainable options.

1 investor

LiveSpo develops spore probiotic products and technologies designed to promote gut health and reduce reliance on antibiotics. The company serves consumers and healthcare applications through various probiotic formulations based on proprietary sporulation and activation technologies.

1 investor

Livia manufactures a wearable menstrual pain relief device using patented micro-pulse technology as a drug-free alternative to pain medication. The device is FDA-approved, reusable, and targeted at individuals managing menstrual discomfort.

1 investor

Lmito Therapeutics is a drug discovery company focused on mitochondrial and cell metabolism, targeting areas such as immunology, neuroimmunology, and immuno-oncology. It operates using a fully integrated pharmaceutical network (FIPNet) business model.

1 investor

LoBio provides at-home plasma collection devices that enable patients to self-collect samples without needing to mail equipment, validated by labs for clinical chemistry testing including lipid, liver, STD, and kidney panels.

1 investor

Loci Orthopaedics develops extremity orthopaedic technologies, including its InDx device for the thumb base joint, using evidence-based design to address unmet clinical needs. The company, which originated from the BioInnovate program in Ireland, focuses on novel implant and surgical devices for hand and wrist conditions.

1 investor

Lone Peak Dental Group operates a network of pediatric dental practices across 14 U.S. states, serving underserved and community-based populations through a dental partnership organization model that emphasizes local ownership and equity participation.

1 investor

A clinical software platform that aggregates patient data from wearables, labs, and clinical inputs to generate medical summaries and support care decision-making. The system provides tools for practitioners to review, edit, and export patient information alongside AI-generated insights.

1 investor

Longwood Fund is a biotech-focused investment firm that both creates and invests in early-stage biotechnology companies developing therapies for unmet medical needs. The team combines decades of experience in biotech investing, operating, and building, working with companies from seed through clinical proof of concept.

1 investor

Loop Diagnostics develops an in vitro cellular immunoassay that detects immunosuppression from bloodstream infections, including sepsis, within the first hour of infection to enable earlier treatment. The company serves healthcare providers with a diagnostic tool for early sepsis detection.

1 investor

Lopital designs and manufactures care equipment such as shower and toilet chairs, shower trolleys and stretchers, dressing tables, and manual transfer aids, aimed at reducing physical strain for caregivers. It also offers an interactive product portfolio and learning tools to raise awareness about static workload.

1 investor

LORAI Health develops next-generation transdermal drug delivery technologies for medicines such as hormones, pain therapies, and neurological treatments, with a focus on reliable delivery, patient comfort, and manufacturing resilience. Founded in Australia, it originated in menopausal hormone therapy and works with research, manufacturing, healthcare, and investment partners internationally.

1 investor

Loresa develops minimally invasive surgical devices for resource-limited settings, with a focus on eliminating the need for insufflation in abdominal surgery. The company serves lower-middle-income countries where access to safe surgery is limited by cost and infrastructure constraints.

1 investor

Thryv Therapeutics is a clinical-stage biotechnology company developing selective inhibitors of serum glucocorticoid inducible kinase 1 (SGK1) for inherited cardiac arrhythmias such as Long QT Syndrome and acquired cardiometabolic diseases. Its lead compound, THRV-1268, is in a Phase 2/3 clinical study for Long QT Syndrome Type 2.

1 investor

LTL Pharma acquires and develops long-established pharmaceutical drugs (long-life medications) from originator manufacturers, maintaining consistent supply and quality standards for healthcare providers and patients. The company specializes in managing mature pharmaceutical products with extensive clinical track records.

1 investor

Lucid Diagnostics develops tests for the early detection of esophageal precancer using targeted next-generation sequencing, aimed at helping clinicians detect and treat the condition before it progresses to cancer. The company operates a CLIA-certified, CAP-accredited clinical lab licensed by the New York State Department of Health.

1 investor

Lucid Genomics provides a software platform for genomic analysis tailored to clinicians, specializing in long-read sequencing interpretation for rare disease, hereditary cancer, and pharmacogenomics diagnostics. The platform integrates variant calling, prioritization, interpretation, and reporting with HPO-based phenotype matching and advanced visualization tools for structural variants.

1 investor

LucidHealth is a physician-led healthcare organization that supports a national network of radiology practices across the United States through corporate services including operations, finance, technology, and strategy. The company focuses on empowering radiologists and advancing clinical outcomes in radiology care.

1 investor

Lucina Biotherapeutics develops therapeutics to treat aging-related disorders, particularly dry age-related macular degeneration (AMD), by restoring very long-chain polyunsaturated fatty acids (VLC-PUFAs) in tissues through its PUFActive platform. The company employs two approaches: synthetic VLC-PUFA formulations for intravitreal injection and engineered microorganism biofactories for oral delivery.

1 investor

Ludocare develops digital therapeutics for pediatric asthma management, combining an interactive health companion app for children with a parental app for monitoring and treatment optimization. The company targets healthcare systems and pediatricians in France seeking to improve asthma control and medication adherence in children ages 4-11.

1 investor

Luma Vision develops advanced imaging technologies focused on cardiology to provide cardiologists with comprehensive, evidence-based understanding of patient heart conditions. The company serves healthcare providers and addresses unmet clinical needs in cardiac imaging.

1 investor

LUMABS BV develops RAPPID, a rapid, one-step immunoassay technology that enables sensitive antibody detection from minimal blood samples for diagnostics and therapeutic monitoring. The company serves immunoassay diagnostic companies, clinical laboratories, biotech organizations, and research groups seeking faster, more sensitive alternatives to traditional ELISA-based assays.

1 investor

Lumen develops orally delivered antibody drugs using engineered spirulina, a patented biologic platform that reduces manufacturing costs and timelines compared to conventional biologics. The company serves biopharma customers seeking alternatives to traditional drug manufacturing.

1 investor

Lumena Pharmaceuticals develops pharmaceutical, nutraceutical, and testing service products using biotechnology, with a focus on ethical practices in research, manufacturing, and distribution across health care markets. The company prioritizes environmental sustainability, reduced chemical use, and responsible innovation in bioavailable product development.

1 investor