Medical Devices Startups

Leica Microsystems manufactures optical microscopy instruments and fluorescence reagents for scientific research and diagnostics. The company serves laboratories, research institutions, and diagnostic facilities requiring advanced imaging and analytical equipment.

1 investor

Leinco Technologies manufactures antibodies and proteins, offering both large- and small-scale IVD antibody and protein production along with CDMO services for scientists in life sciences discovery, biopharmaceutical, and diagnostics segments. Its reagents support research in areas such as cancer, infectious diseases, and immunology.

1 investor

LenioBio develops ALiCE, a cell-free protein expression platform that accelerates the discovery, development, and manufacturing of proteins and biologics for pharmaceutical and vaccine manufacturers. The platform addresses production bottlenecks in drug and vaccine development by enabling faster, scalable biomanufacturing beyond traditional cell-based approaches.

1 investor

LensGen is an ophthalmic medical device company that has developed Juvene, a curvature-changing fluid-optic intraocular lens designed to treat cataracts and presbyopia. The biomimetic lens is placed in the position of the eye's natural lens and adjusts its dioptric power using the eye's own muscle contractions.

1 investor

LeonaBio develops novel therapeutics for treatment-resistant metastatic breast cancer and amyotrophic lateral sclerosis (ALS). The company targets patients with diseases that have significant unmet medical needs.

1 investor

Leucine offers AI Investigator, a quality management platform that automates root cause analysis and provides data-driven corrective action recommendations for manufacturing and quality assurance teams.

1 investor

Leuko develops PointCheck, a noninvasive finger-based device that measures white blood cell levels using light imaging and AI to assess infection risk in cancer patients. The platform is designed for at-home monitoring and supports clinical care decisions for immunocompromised populations.

1 investor

LeviSense Medical is a Massachusetts-based medical device company developing next-generation technology for therapeutic beds used in wound care. Its products target the needs of bedridden patients, caregivers and healthcare providers.

1 investor

Levron Medical develops a Cardio-Respiratory Physiological Assist (CRPA) technology that synchronizes heart rhythm to respiratory dynamics to relieve pulmonary congestion in patients with chronic heart failure. The company builds implantable cardiac medical devices and is running first-in-human studies for heart failure treatment.

1 investor

Lex Diagnostics develops in vitro diagnostic assays, including point-of-care molecular diagnostics, immunodiagnostics, and antimicrobial susceptibility testing. It works on assay development, reagent chemistry, and manufacturing transfer for regulated diagnostic products.

1 investor

LFAnt Medical develops the Compact, a handheld, Bluetooth-connected diagnostic testing platform with embedded biosensing and automated results interpretation for the early detection of diseases and conditions such as sexually transmitted infections. The device supports at-home testing and connects users to telemedicine providers, targeting accessible testing in underserved areas.

1 investor

Liberate Bio develops lipid nanoparticle (LNP) delivery technologies for in vivo cell therapies and genetic medicines, with a focus on myeloid-optimized CAR-M programs that target tissues beyond the liver. The company works on targeted nucleic acid delivery for therapeutic applications.

1 investor

Libra Therapeutics develops small molecule therapeutics targeting lysosomal function and autophagy to treat neurodegenerative diseases including ALS, Parkinson's, Alzheimer's, and Huntington's disease. The company's approach aims to restore cellular balance by enhancing the body's natural ability to clear toxic proteins and dysfunctional organelles.

1 investor

Lice Clinics of America operates a network of clinics providing professional head lice treatment using the AirAllé device, which uses heated air instead of chemical treatments. The company serves parents, caregivers, and schools seeking safe and fast lice removal services.

1 investor

Life Line Screening is a preventive healthcare company that offers disease screening services to help individuals detect health conditions early. The company serves corporate clients, unions, and the general public through both direct-to-consumer and workplace-based screening programs.

1 investor

LifeFlow develops a non-invasive diagnostic technology for assessing the severity of coronary artery disease, providing anatomical and functional evaluation of coronary arteries to help avoid unnecessary invasive procedures. It targets cardiovascular disease diagnostics in the medical technology field.

1 investor

Lifelet Medical develops heart valve leaflets made from a fully synthetic, polymer-based material that is free from animal tissue, aimed at improving valve durability and clinical outcomes. The company targets the prosthetic heart valve market with a product intended to reduce manufacturing costs and avoid re-do procedures.

1 investor

Lifeline manufactures a fully automated hematology analyzer for use in clinical settings including physician offices, clinics, urgent care centers, emergency rooms, hospitals, and research institutions.

1 investor

LifeSignals develops silicon-based biosensor platforms and wearable monitoring solutions that enable clinical-grade health measurement outside traditional healthcare settings. The company targets widespread access to hospital-quality biomedical monitoring for individuals regardless of geographic proximity to medical facilities or economic status.

1 investor

Life Spine develops minimally invasive surgical products and procedural solutions for spinal fusion procedures across cervical, thoracolumbar, and lateral applications. The company serves surgeons and patients undergoing spine surgery, operating in the medical device and surgical equipment industry.

1 investor

Lifetrack Medical Systems builds cloud-based medical imaging software platforms for the healthcare ecosystem, with initial focus on radiology solutions in emerging markets. The company develops distributed enterprise software to reduce operational complexity and costs for healthcare providers.

1 investor

LifeWave develops an AI-powered system of care for chronic heart failure management that combines a non-invasive biomarker sensor measuring lung fluid with agentic AI to guide medication titration and therapy optimization. The platform is designed for use across diverse healthcare settings including homes, primary care, and remote monitoring to help patients and clinicians detect worsening heart failure early and reduce hospitalizations.

1 investor

Lifotronic is a Chinese medical diagnostics and healthcare company that develops in vitro diagnostic products, clinical medical devices, dermatology and aesthetic solutions, and consumer health offerings.

1 investor

LigaChemBio is a biopharmaceutical company focused on developing antibody-drug conjugates (ADCs) and small molecule therapeutics, with proprietary ADC technology and a drug development pipeline. The page shown is an investor disclosure section listing regulatory filings.

1 investor